{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Manipulation+Under+Anesthesia",
    "query": {
      "intervention": "Manipulation Under Anesthesia"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Manipulation+Under+Anesthesia&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-02T11:15:46.188Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07721272",
      "title": "Human Cognition During Surgery: Stimulation-based and Cholinergic Modulation",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Epilepsy",
        "Essential Tremor",
        "Seizures",
        "Memory Consolidation",
        "Memory Disorders",
        "Memory Replay",
        "Memory Encoding",
        "Cognitive Control",
        "Motor Abilities"
      ],
      "interventions": [
        {
          "name": "Cobenfy KarXT pill (50/20 mg)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 30,
      "start_date": "2026-10",
      "completion_date": "2030-09",
      "has_results": false,
      "last_update_posted_date": "2026-07-23",
      "last_synced_at": "2026-09-02T11:15:46.188Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07721272"
    },
    {
      "nct_id": "NCT01961219",
      "title": "Manipulation Under Anesthesia Versus Arthroscopic Capsular Release in the Treatment of Adhesive Capsulitis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adhesive Capsulitis of the Shoulder"
      ],
      "interventions": [
        {
          "name": "Manipulation Under Anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Arthroscopic capsular release",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Akin Cil",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 13,
      "start_date": "2013-11",
      "completion_date": "2022-04-25",
      "has_results": false,
      "last_update_posted_date": "2023-11-02",
      "last_synced_at": "2026-09-02T11:15:46.188Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01961219"
    },
    {
      "nct_id": "NCT07151417",
      "title": "Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery.",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Knee Osteoarthritis",
        "Musculoskeletal Disease",
        "Surgery"
      ],
      "interventions": [
        {
          "name": "PAI",
          "type": "DRUG"
        },
        {
          "name": "PAI + steroid",
          "type": "DRUG"
        },
        {
          "name": "PAI + zilretta",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Walter Reed National Military Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 240,
      "start_date": "2026-09-01",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-19",
      "last_synced_at": "2026-09-02T11:15:46.188Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07151417"
    },
    {
      "nct_id": "NCT02926248",
      "title": "Effect of Colchicine on Range of Motion After Manipulation Under Anesthesia for the Stiff Total Knee Replacement",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Manipulation Under Anesthesia"
      ],
      "interventions": [
        {
          "name": "Colchicine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 112,
      "start_date": "2016-05",
      "completion_date": "2021-03",
      "has_results": false,
      "last_update_posted_date": "2020-07-28",
      "last_synced_at": "2026-09-02T11:15:46.188Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02926248"
    },
    {
      "nct_id": "NCT05419609",
      "title": "Comparison of an Office-based Limited Facelift and Hospital-based Full Facelift",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Skin Aging",
        "Facial Asymmetry",
        "Aging Problems"
      ],
      "interventions": [
        {
          "name": "Limited facelift",
          "type": "PROCEDURE"
        },
        {
          "name": "Full facelift",
          "type": "PROCEDURE"
        },
        {
          "name": "FACE-Q | Aesthetics - Satisfaction With Lower Face and Jawline",
          "type": "OTHER"
        },
        {
          "name": "FACE-Q | Aesthetics - Recovery Early Symptoms",
          "type": "OTHER"
        },
        {
          "name": "FACE-Q | Aesthetics - Satisfaction with Outcome",
          "type": "OTHER"
        },
        {
          "name": "FACE-Q | Aesthetics - Adverse Effects: Cheeks, Lower Face, Neck",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Dufresne, Craig, MD, PC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "40 Years to 85 Years"
      },
      "enrollment_count": 100,
      "start_date": "2022-06-30",
      "completion_date": "2023-07",
      "has_results": false,
      "last_update_posted_date": "2022-07-19",
      "last_synced_at": "2026-09-02T11:15:46.188Z",
      "location_count": 1,
      "location_summary": "Fairfax, Virginia",
      "locations": [
        {
          "city": "Fairfax",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05419609"
    },
    {
      "nct_id": "NCT02739035",
      "title": "MUA to Treat Postoperative Stiffness After Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Stiffness Following Total Knee Arthroplasty"
      ],
      "interventions": [
        {
          "name": "Dexamethasone",
          "type": "DRUG"
        },
        {
          "name": "Celecoxib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 130,
      "start_date": "2016-04",
      "completion_date": "2022-12",
      "has_results": true,
      "last_update_posted_date": "2023-11-21",
      "last_synced_at": "2026-09-02T11:15:46.188Z",
      "location_count": 16,
      "location_summary": "Little Rock, Arkansas • Denver, Colorado • Chicago, Illinois + 11 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02739035"
    },
    {
      "nct_id": "NCT07348614",
      "title": "Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Knee Stiffness After Total Knee Arthroplasty"
      ],
      "interventions": [
        {
          "name": "Spinal Anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "General Anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Propofol",
          "type": "DRUG"
        },
        {
          "name": "Chloroprocaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 128,
      "start_date": "2026-06-01",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2026-06-03",
      "last_synced_at": "2026-09-02T11:15:46.188Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07348614"
    },
    {
      "nct_id": "NCT03519347",
      "title": "Reducing Arrhythmia in Dialysis by Adjusting the Rx Electrolytes/Ultrafiltration, Study A",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "End Stage Renal Disease"
      ],
      "interventions": [
        {
          "name": "Potassium Removal Maximization",
          "type": "OTHER"
        },
        {
          "name": "Potassium Gradient Minimization",
          "type": "OTHER"
        },
        {
          "name": "Alkalosis Avoidance",
          "type": "OTHER"
        },
        {
          "name": "Acidosis avoidance",
          "type": "OTHER"
        },
        {
          "name": "Point of Care Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Cardiac Monitor",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIAGNOSTIC_TEST",
        "DEVICE"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 19,
      "start_date": "2018-11-30",
      "completion_date": "2022-10-14",
      "has_results": true,
      "last_update_posted_date": "2023-08-15",
      "last_synced_at": "2026-09-02T11:15:46.188Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03519347"
    },
    {
      "nct_id": "NCT05384093",
      "title": "Outcomes of Treatment Using the ERMI Shoulder Flexionater ®",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adhesive Capsulitis of Shoulder"
      ],
      "interventions": [
        {
          "name": "High Intensity Stretch Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Foundation for Orthopaedic Research and Education",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 210,
      "start_date": "2019-06-25",
      "completion_date": "2026-06-25",
      "has_results": false,
      "last_update_posted_date": "2025-08-07",
      "last_synced_at": "2026-09-02T11:15:46.188Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05384093"
    },
    {
      "nct_id": "NCT01434966",
      "title": "Changes in Quadriceps Function Following Local or Distant Interventions in Individuals With Patellofemoral Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patellofemoral Pain Syndrome",
        "Chondromalacia Patellae",
        "Anterior Knee Pain Syndrome"
      ],
      "interventions": [
        {
          "name": "Lumbopelvic Manipulation",
          "type": "OTHER"
        },
        {
          "name": "TENS- Spine",
          "type": "OTHER"
        },
        {
          "name": "TENS- Knee",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Creighton University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "15 Years to 50 Years"
      },
      "enrollment_count": 47,
      "start_date": "2011-09",
      "completion_date": "2015-07",
      "has_results": false,
      "last_update_posted_date": "2015-12-14",
      "last_synced_at": "2026-09-02T11:15:46.188Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01434966"
    }
  ]
}