{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Manual+Compression&page=3",
    "query": {
      "intervention": "Manual Compression",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 64,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Manual+Compression&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Manual+Compression&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-19T18:01:47.971Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00597207",
      "title": "Circulation Improving Resuscitation Care (CIRC)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiac Arrest",
        "Cardiopulmonary Resuscitation"
      ],
      "interventions": [
        {
          "name": "AutoPulse",
          "type": "DEVICE"
        },
        {
          "name": "Manual",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Zoll Medical Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4231,
      "start_date": "2008-01",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2018-07-24",
      "last_synced_at": "2026-10-19T18:01:47.971Z",
      "location_count": 3,
      "location_summary": "Tampa, Florida • Houston, Texas • Menasha, Wisconsin",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Menasha",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00597207"
    },
    {
      "nct_id": "NCT01096628",
      "title": "Chiropractic and Exercise for Low Back Pain in Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Chiropractic + Exercise",
          "type": "OTHER"
        },
        {
          "name": "Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northwestern Health Sciences University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "12 Years to 18 Years"
      },
      "enrollment_count": 185,
      "start_date": "2010-03",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2014-01-31",
      "last_synced_at": "2026-10-19T18:01:47.971Z",
      "location_count": 2,
      "location_summary": "Bloomington, Minnesota • Portland, Oregon",
      "locations": [
        {
          "city": "Bloomington",
          "state": "Minnesota"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01096628"
    },
    {
      "nct_id": "NCT04957732",
      "title": "The Effect of Wound Irrigation With Irrisept on Abscess Healing (Irrisept UF Study)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Abscess"
      ],
      "interventions": [
        {
          "name": "Standard of Care (SoC)",
          "type": "DEVICE"
        },
        {
          "name": "Irrisept Delivery System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Irrimax Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 35,
      "start_date": "2010-01",
      "completion_date": "2011-11",
      "has_results": true,
      "last_update_posted_date": "2022-02-02",
      "last_synced_at": "2026-10-19T18:01:47.971Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04957732"
    },
    {
      "nct_id": "NCT02255487",
      "title": "Irrisept Versus Standard of Care in the Prevention of Surgical Site Infections",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgical Site Infection"
      ],
      "interventions": [
        {
          "name": "IrriSept System",
          "type": "DEVICE"
        },
        {
          "name": "No Intervention - Standard of Care (SoC) only",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Irrimax Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 627,
      "start_date": "2015-02-18",
      "completion_date": "2017-03-13",
      "has_results": true,
      "last_update_posted_date": "2022-05-24",
      "last_synced_at": "2026-10-19T18:01:47.971Z",
      "location_count": 17,
      "location_summary": "Tucson, Arizona • Los Angeles, California • Denver, Colorado + 14 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02255487"
    },
    {
      "nct_id": "NCT03193021",
      "title": "AMBULATE: Cardiva Mid-Bore VVCS vs. Manual Compression for Multiple Femoral Venous Access Sites, 6 - 12F ID",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgical Wound"
      ],
      "interventions": [
        {
          "name": "Cardiva Mid-Bore VVCS",
          "type": "DEVICE"
        },
        {
          "name": "Manual compression",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Cardiva Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 204,
      "start_date": "2017-09-20",
      "completion_date": "2018-04-13",
      "has_results": true,
      "last_update_posted_date": "2023-03-10",
      "last_synced_at": "2026-10-19T18:01:47.971Z",
      "location_count": 13,
      "location_summary": "Anchorage, Alaska • Sacramento, California • Stanford, California + 10 more",
      "locations": [
        {
          "city": "Anchorage",
          "state": "Alaska"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03193021"
    },
    {
      "nct_id": "NCT06837870",
      "title": "Percutaneous Closure Versus Figure-of-eight Suture for Hemostasis in Leadless Pacemaker Implantation.",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vascular Closure",
        "Pacemaker Implantation",
        "Leadless Pacemaker"
      ],
      "interventions": [
        {
          "name": "percutaneous suture mediated closure",
          "type": "DEVICE"
        },
        {
          "name": "Figure of Eight Suture",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Massachusetts, Worcester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2025-07-11",
      "completion_date": "2027-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-27",
      "last_synced_at": "2026-10-19T18:01:47.971Z",
      "location_count": 1,
      "location_summary": "Worcester, Massachusetts",
      "locations": [
        {
          "city": "Worcester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06837870"
    },
    {
      "nct_id": "NCT00842179",
      "title": "Groin Complications Post Percutaneous Coronary Intervention Using Either Manual Compression or PERCLOSE Device",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Vascular Closure"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Clinyx, LLC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2517,
      "start_date": "2008-06",
      "completion_date": "2008-10",
      "has_results": false,
      "last_update_posted_date": "2009-02-12",
      "last_synced_at": "2026-10-19T18:01:47.971Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00842179"
    },
    {
      "nct_id": "NCT04213989",
      "title": "Intermittent Pneumatic Compression in Women With Lipo-lymphedema (Lipedema With Swelling)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lipedema",
        "Lipolymphedema"
      ],
      "interventions": [
        {
          "name": "Flexitouch Plus and Conservative Care",
          "type": "DEVICE"
        },
        {
          "name": "Conservative Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Thomas Wright, MD",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 70 Years · Female only"
      },
      "enrollment_count": 36,
      "start_date": "2020-01-31",
      "completion_date": "2021-11-24",
      "has_results": true,
      "last_update_posted_date": "2022-08-23",
      "last_synced_at": "2026-10-19T18:01:47.971Z",
      "location_count": 1,
      "location_summary": "O'Fallon, Missouri",
      "locations": [
        {
          "city": "O'Fallon",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04213989"
    },
    {
      "nct_id": "NCT02307318",
      "title": "Heart and Hands Study II: A Retrospective Data Collection & Analysis Project",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Thrombosis"
      ],
      "interventions": [
        {
          "name": "SoftSeal Hemostatic Pad",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "HealthEast Care System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 51,
      "start_date": "2014-11",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2017-01-11",
      "last_synced_at": "2026-10-19T18:01:47.971Z",
      "location_count": 1,
      "location_summary": "Saint Paul, Minnesota",
      "locations": [
        {
          "city": "Saint Paul",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02307318"
    },
    {
      "nct_id": "NCT03760744",
      "title": "Imaging Biomarkers of Lymphatic Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Secondary Lymphedema"
      ],
      "interventions": [
        {
          "name": "CDT with Negative Pressure",
          "type": "PROCEDURE"
        },
        {
          "name": "CDT alone",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "90 Years",
        "sex": "FEMALE",
        "summary": "30 Years to 90 Years · Female only"
      },
      "enrollment_count": 18,
      "start_date": "2019-01-23",
      "completion_date": "2025-03-15",
      "has_results": true,
      "last_update_posted_date": "2025-10-16",
      "last_synced_at": "2026-10-19T18:01:47.971Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03760744"
    }
  ]
}