{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Manual+Lymphatic+Drainage",
    "query": {
      "intervention": "Manual Lymphatic Drainage"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 33,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Manual+Lymphatic+Drainage&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-13T20:40:24.957Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02360735",
      "title": "Manual Lymph Drainage",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Knee Arthroplasty",
        "Post-operative Edema"
      ],
      "interventions": [
        {
          "name": "Manual Lymphatic Drainage",
          "type": "OTHER"
        },
        {
          "name": "Physical Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Anne Arundel Health System Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "45 Years to 90 Years"
      },
      "enrollment_count": 4,
      "start_date": "2015-01",
      "completion_date": "2016-10-11",
      "has_results": false,
      "last_update_posted_date": "2018-01-09",
      "last_synced_at": "2026-09-13T20:40:24.957Z",
      "location_count": 1,
      "location_summary": "Annapolis, Maryland",
      "locations": [
        {
          "city": "Annapolis",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02360735"
    },
    {
      "nct_id": "NCT06144164",
      "title": "A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Lymphedema",
        "Lymphedema Arm",
        "Lymphedema of Upper Arm",
        "Breast Cancer",
        "Breast Carcinoma",
        "Female Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Immediate Lymphatic Reconstruction",
          "type": "PROCEDURE"
        },
        {
          "name": "Volumetric arm measurements",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Lymphatic massage",
          "type": "OTHER"
        },
        {
          "name": "Range of motion exercises",
          "type": "OTHER"
        },
        {
          "name": "Compression garment use",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 75 Years · Female only"
      },
      "enrollment_count": 285,
      "start_date": "2023-11-16",
      "completion_date": "2030-03-16",
      "has_results": false,
      "last_update_posted_date": "2025-11-10",
      "last_synced_at": "2026-09-13T20:40:24.957Z",
      "location_count": 7,
      "location_summary": "Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more",
      "locations": [
        {
          "city": "Basking Ridge",
          "state": "New Jersey"
        },
        {
          "city": "Middletown",
          "state": "New Jersey"
        },
        {
          "city": "Montvale",
          "state": "New Jersey"
        },
        {
          "city": "Commack",
          "state": "New York"
        },
        {
          "city": "Harrison",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06144164"
    },
    {
      "nct_id": "NCT03760744",
      "title": "Imaging Biomarkers of Lymphatic Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Secondary Lymphedema"
      ],
      "interventions": [
        {
          "name": "CDT with Negative Pressure",
          "type": "PROCEDURE"
        },
        {
          "name": "CDT alone",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "90 Years",
        "sex": "FEMALE",
        "summary": "30 Years to 90 Years · Female only"
      },
      "enrollment_count": 18,
      "start_date": "2019-01-23",
      "completion_date": "2025-03-15",
      "has_results": true,
      "last_update_posted_date": "2025-10-16",
      "last_synced_at": "2026-09-13T20:40:24.957Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03760744"
    },
    {
      "nct_id": "NCT02591056",
      "title": "Study of the Combined Effect of Low Level Laser Therapy and Manual Lymph Drainage on Reducing Body Circumference",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Circumference Reduction"
      ],
      "interventions": [
        {
          "name": "Erchonia® Verju™ Laser",
          "type": "DEVICE"
        },
        {
          "name": "Green PRESS 8",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Erchonia Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 27,
      "start_date": "2016-01",
      "completion_date": "2016-06",
      "has_results": true,
      "last_update_posted_date": "2020-02-10",
      "last_synced_at": "2026-09-13T20:40:24.957Z",
      "location_count": 3,
      "location_summary": "Stockton, California • Marion, Indiana • Bloomfield Hills, Michigan",
      "locations": [
        {
          "city": "Stockton",
          "state": "California"
        },
        {
          "city": "Marion",
          "state": "Indiana"
        },
        {
          "city": "Bloomfield Hills",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02591056"
    },
    {
      "nct_id": "NCT05242900",
      "title": "Imaging Sodium and Lymphatics in Lymphedema",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lymphedema of Leg",
        "Lymphedema, Secondary",
        "Lymphedema Related Fibrosis"
      ],
      "interventions": [
        {
          "name": "Complete decongestive therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard imaging protocol",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 80 Years · Female only"
      },
      "enrollment_count": 75,
      "start_date": "2021-10-10",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2025-04-27",
      "last_synced_at": "2026-09-13T20:40:24.957Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05242900"
    },
    {
      "nct_id": "NCT00058851",
      "title": "Massage Therapy for Breast Cancer Treatment-Related Swelling of the Arms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Lymphedema"
      ],
      "interventions": [
        {
          "name": "Manual lymph drainage",
          "type": "PROCEDURE"
        },
        {
          "name": "Combined physiotherapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Compression bandaging",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "National Center for Complementary and Integrative Health (NCCIH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 88,
      "start_date": "2003-01",
      "completion_date": "2007-11",
      "has_results": false,
      "last_update_posted_date": "2009-08-19",
      "last_synced_at": "2026-09-13T20:40:24.957Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00058851"
    },
    {
      "nct_id": "NCT01019512",
      "title": "Flexitouch Lymphedema System in Treating Stage II Lymphedema in Patients With Breast Cancer",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Lymphedema"
      ],
      "interventions": [
        {
          "name": "questionnaire administration",
          "type": "OTHER"
        },
        {
          "name": "lymphedema management",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Abramson Cancer Center at Penn Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 60,
      "start_date": "2009-07",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2015-03-25",
      "last_synced_at": "2026-09-13T20:40:24.957Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01019512"
    },
    {
      "nct_id": "NCT00383500",
      "title": "Lymphedema Prophylaxis in Breast Cancer Survivors Who Show Early Evidence of High-risk Status",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lymphedema",
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Flexitouch",
          "type": "DEVICE"
        },
        {
          "name": "Class 1 compression garment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 75,
      "start_date": "2005-05",
      "completion_date": "2009-09",
      "has_results": true,
      "last_update_posted_date": "2017-03-30",
      "last_synced_at": "2026-09-13T20:40:24.957Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00383500"
    },
    {
      "nct_id": "NCT03332160",
      "title": "A Pilot Study to Evaluate the Feasibility and Potential Effectiveness of the Flexitouch System Head and Neck Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Head and Neck Neoplasms",
        "Head and Neck Cancer",
        "Head and Neck Lymphedema"
      ],
      "interventions": [
        {
          "name": "Flexitouch head and neck lymphedema treatment system",
          "type": "DEVICE"
        },
        {
          "name": "Standard home lymphedema care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Tactile Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 49,
      "start_date": "2018-01-02",
      "completion_date": "2019-07-31",
      "has_results": true,
      "last_update_posted_date": "2020-08-06",
      "last_synced_at": "2026-09-13T20:40:24.957Z",
      "location_count": 2,
      "location_summary": "Springfield, Illinois • Nashville, Tennessee",
      "locations": [
        {
          "city": "Springfield",
          "state": "Illinois"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03332160"
    },
    {
      "nct_id": "NCT06405282",
      "title": "Weightlessness Associated Cephalad Fluid Shifts; The Potential to Evaluate Venous and Lymphatic Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fluid Retention Tissue",
        "Perfusion; Complications"
      ],
      "interventions": [
        {
          "name": "Manual Lymphatic Drainage",
          "type": "OTHER"
        },
        {
          "name": "Near infrared spectroscopy",
          "type": "DEVICE"
        },
        {
          "name": "Temperature",
          "type": "DEVICE"
        },
        {
          "name": "Tissue Dialectic Constant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Nova Southeastern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 15,
      "start_date": "2022-04-14",
      "completion_date": "2022-06-25",
      "has_results": false,
      "last_update_posted_date": "2024-05-08",
      "last_synced_at": "2026-09-13T20:40:24.957Z",
      "location_count": 1,
      "location_summary": "Fort Lauderdale, Florida",
      "locations": [
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06405282"
    }
  ]
}