{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Manual+Therapy%2C+Exercise+and+Ultrasound",
    "query": {
      "intervention": "Manual Therapy, Exercise and Ultrasound"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-28T02:22:29.552Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07642583",
      "title": "Dry Needling and Exercise for Mid-portion Achilles Tendinopathy",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Non-Insertional Achilles Tendinopathy"
      ],
      "interventions": [
        {
          "name": "Dry needling",
          "type": "OTHER"
        },
        {
          "name": "Sham dry needling",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brooke Army Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 74,
      "start_date": "2026-06-02",
      "completion_date": "2027-07-07",
      "has_results": false,
      "last_update_posted_date": "2026-06-12",
      "last_synced_at": "2026-09-28T02:22:29.552Z",
      "location_count": 1,
      "location_summary": "Fort Sam Houston, Texas",
      "locations": [
        {
          "city": "Fort Sam Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07642583"
    },
    {
      "nct_id": "NCT03059004",
      "title": "Comparing Different Types of Physical Therapy for Treating People With a Meniscal Tear and Osteoarthritis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Meniscal Degeneration",
        "Osteoarthritis, Knee"
      ],
      "interventions": [
        {
          "name": "TeMPO Home Exercise Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Motivational SMS Messages",
          "type": "BEHAVIORAL"
        },
        {
          "name": "In-Clinic Topical Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "In-Clinic Exercise Therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "45 Years to 85 Years"
      },
      "enrollment_count": 879,
      "start_date": "2018-02-06",
      "completion_date": "2024-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-07-03",
      "last_synced_at": "2026-09-28T02:22:29.552Z",
      "location_count": 4,
      "location_summary": "Boston, Massachusetts • Buffalo, New York • Cleveland, Ohio + 1 more",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03059004"
    },
    {
      "nct_id": "NCT04386590",
      "title": "Manual Therapy in Addition to Pulmonary Rehabilitation in Moderate Chronic Obstructive Pulmonary Disease.",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease Moderate"
      ],
      "interventions": [
        {
          "name": "Manual Therapy Plus Pulmonary Rehabilitation",
          "type": "OTHER"
        },
        {
          "name": "Sham Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Canandaigua VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "50 Years to 70 Years"
      },
      "enrollment_count": 20,
      "start_date": "2022-06-15",
      "completion_date": "2023-11-02",
      "has_results": false,
      "last_update_posted_date": "2022-03-31",
      "last_synced_at": "2026-09-28T02:22:29.552Z",
      "location_count": 1,
      "location_summary": "Syracuse, New York",
      "locations": [
        {
          "city": "Syracuse",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04386590"
    },
    {
      "nct_id": "NCT07227662",
      "title": "Feasibility, Usability and Preliminary Efficacy of Home-based FES Fro Adhesive Capsulitis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Shoulder Adhesive Capsulitis"
      ],
      "interventions": [
        {
          "name": "Home based FES in combination with usual therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2026-06-01",
      "completion_date": "2026-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-25",
      "last_synced_at": "2026-09-28T02:22:29.552Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07227662"
    },
    {
      "nct_id": "NCT03167710",
      "title": "Dry Needling, Manipulation and Stretching vs. Manual Therapy, Exercise and Ultrasound for Lateral Epicondylalgia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lateral Epicondylitis"
      ],
      "interventions": [
        {
          "name": "Dry Needling, manipulation, stretching",
          "type": "OTHER"
        },
        {
          "name": "manual therapy, exercise, ultrasound",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Alabama Physical Therapy & Acupuncture",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 143,
      "start_date": "2017-06-15",
      "completion_date": "2021-03-15",
      "has_results": false,
      "last_update_posted_date": "2023-09-05",
      "last_synced_at": "2026-09-28T02:22:29.552Z",
      "location_count": 1,
      "location_summary": "Cockeysville, Maryland",
      "locations": [
        {
          "city": "Cockeysville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03167710"
    },
    {
      "nct_id": "NCT04609735",
      "title": "Manual Therapy, Exercise and US Vs. Manual Therapy, Exercise and US for Medial Epicondylalgia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Epicondylalgia"
      ],
      "interventions": [
        {
          "name": "Electric Dry Needling, Manual Therapy, Exercise and Ultrasound",
          "type": "OTHER"
        },
        {
          "name": "Manual Therapy, Exercise and Ultrasound",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Alabama Physical Therapy & Acupuncture",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 110,
      "start_date": "2020-10-31",
      "completion_date": "2026-05-01",
      "has_results": false,
      "last_update_posted_date": "2025-05-18",
      "last_synced_at": "2026-09-28T02:22:29.552Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04609735"
    },
    {
      "nct_id": "NCT04175288",
      "title": "The Effectiveness of Ultrasound Treatment in the Management of Plantar Fasciitis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Plantar Fascitis"
      ],
      "interventions": [
        {
          "name": "Ultrasound, manual therapy and exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Sage Colleges",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2019-11-18",
      "completion_date": "2021-12-31",
      "has_results": false,
      "last_update_posted_date": "2019-11-25",
      "last_synced_at": "2026-09-28T02:22:29.552Z",
      "location_count": 1,
      "location_summary": "Troy, New York",
      "locations": [
        {
          "city": "Troy",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04175288"
    },
    {
      "nct_id": "NCT05639556",
      "title": "Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cystic Fibrosis"
      ],
      "interventions": [
        {
          "name": "BMI and lean mass index from DXA",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Anthropometric Measurements",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Hand-grip strength",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Six-minute walk Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Sit-to-Stand Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Short physical performance battery (SPPB)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "BIA Sub-study",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Accelerometry to assess physical activity",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Gastrointestinal (GI) and nutrition questionnaires:",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: PHQ-8",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: GAD-7",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: The Treatment Self-Regulation Questionnaire (TSRQ)",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: CF Fatalism Scale",
          "type": "OTHER"
        },
        {
          "name": "Psychosocial questionnaire: Body Esteem Scale for Adolescents and Adults (BESAA)",
          "type": "OTHER"
        },
        {
          "name": "12-month Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Oral glucose tolerance testing (OGTT)",
          "type": "OTHER"
        },
        {
          "name": "Continuous glucose monitoring (CGM)",
          "type": "DEVICE"
        },
        {
          "name": "Chest CT scans (When available within the past 6 months in medical records)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Hologic Dual X-Ray Absorptiometry (DXA)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Ultrasound Sub-study of assessment of appendage muscles using ultrasound",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Psychosocial questionnaire: Hunger Vital Sign questionnaire",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Respiratory symptom questionnaire: CRISS",
          "type": "OTHER"
        },
        {
          "name": "Spirometry",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Psychosocial questionnaire: Additional Health Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "CF Management Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Food Frequency Questionnaire",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2023-04-20",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-13",
      "last_synced_at": "2026-09-28T02:22:29.552Z",
      "location_count": 23,
      "location_summary": "Tucson, Arizona • Little Rock, Arkansas • Atlanta, Georgia + 19 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05639556"
    },
    {
      "nct_id": "NCT01865734",
      "title": "Comparison of Usual Podiatric Care and Early Physical Therapy for Plantar Heel Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fasciitis, Plantar"
      ],
      "interventions": [
        {
          "name": "Physical therapy after initial podiatry visit",
          "type": "OTHER"
        },
        {
          "name": "Usual care provided by podiatry",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Des Moines University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 95,
      "start_date": "2013-12",
      "completion_date": "2017-11",
      "has_results": false,
      "last_update_posted_date": "2019-01-22",
      "last_synced_at": "2026-09-28T02:22:29.552Z",
      "location_count": 1,
      "location_summary": "Des Moines, Iowa",
      "locations": [
        {
          "city": "Des Moines",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01865734"
    },
    {
      "nct_id": "NCT00988468",
      "title": "Manual Therapy Versus Exercise on Knee Osteoarthritis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Manual Therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Therapeutic Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Video Observation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BEHAVIORAL"
      ],
      "sponsor": "Texas Tech University Health Sciences Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 1,
      "start_date": "2009-10",
      "completion_date": "2010-08",
      "has_results": false,
      "last_update_posted_date": "2010-11-16",
      "last_synced_at": "2026-09-28T02:22:29.552Z",
      "location_count": 1,
      "location_summary": "Lubbock, Texas",
      "locations": [
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00988468"
    }
  ]
}