{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Matrix+RF",
    "query": {
      "intervention": "Matrix RF"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 4,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T22:28:14.581Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00887913",
      "title": "Clinical Study to Evaluate the Performance of Fractional Radiofrequency for Improvement of Skin Texture Via Skin Resurfacing and Wrinkles Reduction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Skin Resurfacing",
        "Wrinkle Reduction"
      ],
      "interventions": [
        {
          "name": "Fractional RF treatment with Matrix RF applicator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Syneron Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 69,
      "start_date": "2008-04",
      "completion_date": "2009-10",
      "has_results": true,
      "last_update_posted_date": "2010-11-30",
      "last_synced_at": "2026-09-06T22:28:14.581Z",
      "location_count": 2,
      "location_summary": "Lincolnshire, Illinois • Chesterfield, Missouri",
      "locations": [
        {
          "city": "Lincolnshire",
          "state": "Illinois"
        },
        {
          "city": "Chesterfield",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00887913"
    },
    {
      "nct_id": "NCT06157567",
      "title": "Clinical Feasibility Study to Evaluate the Safety and Performance of the Profound Matrix System",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Skin Laxity",
        "Wrinkle",
        "Skin Condition"
      ],
      "interventions": [
        {
          "name": "Profound Matrix",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Candela Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 500,
      "start_date": "2022-05-24",
      "completion_date": "2028-05-24",
      "has_results": false,
      "last_update_posted_date": "2025-08-22",
      "last_synced_at": "2026-09-06T22:28:14.581Z",
      "location_count": 4,
      "location_summary": "Jacksonville, Florida • Marlborough, Massachusetts • Fayetteville, North Carolina + 1 more",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Marlborough",
          "state": "Massachusetts"
        },
        {
          "city": "Fayetteville",
          "state": "North Carolina"
        },
        {
          "city": "Vienna",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06157567"
    },
    {
      "nct_id": "NCT01101360",
      "title": "Port Wine Stains Treatment Matrix RF Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Port Wine Stains"
      ],
      "interventions": [
        {
          "name": "Matrix RF",
          "type": "DEVICE"
        },
        {
          "name": "Matrix RF followed by Pulse Dye Laser",
          "type": "DEVICE"
        },
        {
          "name": "Pulse Dye Laser followed by Matrix RF",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Syneron Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 10,
      "start_date": "2010-03",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2014-12-02",
      "last_synced_at": "2026-09-06T22:28:14.581Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01101360"
    },
    {
      "nct_id": "NCT06192550",
      "title": "Functional Usability and Feasibility Testing of the Profound Matrix™ System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wrinkle",
        "Acne Scars - Mixed Atrophic and Hypertrophic"
      ],
      "interventions": [
        {
          "name": "Profound Matrix™ System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Candela Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 193,
      "start_date": "2020-10-28",
      "completion_date": "2023-12-29",
      "has_results": false,
      "last_update_posted_date": "2025-02-13",
      "last_synced_at": "2026-09-06T22:28:14.581Z",
      "location_count": 4,
      "location_summary": "Marlborough, Massachusetts • New York, New York • Charlotte, North Carolina",
      "locations": [
        {
          "city": "Marlborough",
          "state": "Massachusetts"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06192550"
    }
  ]
}