{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Mechanical+ventilation+adjustment&page=2",
    "query": {
      "intervention": "Mechanical ventilation adjustment",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Mechanical+ventilation+adjustment&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-29T03:55:12.345Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07277244",
      "title": "Low-Intensity Mechanical Ventilation in the Operating Room: a Pilot Study",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Robotic Surgery",
        "Post Operative Pulmonary Complications"
      ],
      "interventions": [
        {
          "name": "Low Intensity Mechanical Ventilation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2026-04-02",
      "completion_date": "2027-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-21",
      "last_synced_at": "2026-09-29T03:55:12.345Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07277244"
    },
    {
      "nct_id": "NCT02100735",
      "title": "Evaluation of an Analgosedation Protocol in Mechanically Ventilated Patients",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Effect of Protocolized Sedation on Days of Mechanical Ventilation in the ICU"
      ],
      "interventions": [
        {
          "name": "Sedation protocol",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Tampa General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 0,
      "start_date": "2019-09-13",
      "completion_date": "2021-04",
      "has_results": false,
      "last_update_posted_date": "2020-10-19",
      "last_synced_at": "2026-09-29T03:55:12.345Z",
      "location_count": 1,
      "location_summary": "Riverview, Florida",
      "locations": [
        {
          "city": "Riverview",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02100735"
    },
    {
      "nct_id": "NCT07224620",
      "title": "Fentanyl Versus Hydromorphone in Patients on Mechanical Ventilation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Mechanical Ventilation",
        "Sedation and Analgesia",
        "Critical Care, Intensive Care"
      ],
      "interventions": [
        {
          "name": "fentanyl",
          "type": "DRUG"
        },
        {
          "name": "Hydromorphone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 319,
      "start_date": "2025-11-03",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-14",
      "last_synced_at": "2026-09-29T03:55:12.345Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07224620"
    },
    {
      "nct_id": "NCT02907866",
      "title": "Use of Endobronchial Ultrasound Scope (EBUS) Transducer to Identify Pneumothorax-A Feasibility Study",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pneumothorax"
      ],
      "interventions": [
        {
          "name": "Ultrasound with EBUS scope and with linear ultrasound probe",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 17,
      "start_date": "2016-09",
      "completion_date": "2024-02-09",
      "has_results": false,
      "last_update_posted_date": "2026-04-01",
      "last_synced_at": "2026-09-29T03:55:12.345Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02907866"
    },
    {
      "nct_id": "NCT07710469",
      "title": "Weighted Blanket to Improve Sedation and Comfort During Ventilator Weaning",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ventilated Patient in Intensive Care"
      ],
      "interventions": [
        {
          "name": "Weighted blanket",
          "type": "DEVICE"
        },
        {
          "name": "Standard hospital linens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 64,
      "start_date": "2026-08-01",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-10",
      "last_synced_at": "2026-09-29T03:55:12.345Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07710469"
    },
    {
      "nct_id": "NCT01785563",
      "title": "Nasal Noninvasive NAVA in the Very Low Birth Weight Infant",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Inadequate; Pulmonary Ventilation, Newborn",
        "Infant, Very Low Birth Weight"
      ],
      "interventions": [
        {
          "name": "Nasal NIV-NAVA",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Tarah T Colaizy",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Days",
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "7 Days to 1 Year"
      },
      "enrollment_count": 40,
      "start_date": "2013-02",
      "completion_date": "2018-12-31",
      "has_results": true,
      "last_update_posted_date": "2022-06-09",
      "last_synced_at": "2026-09-29T03:55:12.345Z",
      "location_count": 2,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01785563"
    },
    {
      "nct_id": "NCT02354365",
      "title": "Measuring Lung Pressures in Critically Ill Children Who Are on Mechanical Ventilation",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Transpulmonary Pressure",
        "Pressure.Rate Product",
        "Guide to Mechanical Ventilator Management",
        "Extubation Readiness"
      ],
      "interventions": [
        {
          "name": "Transpulmonary Pressure measurement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Week",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Week to 18 Years"
      },
      "enrollment_count": 55,
      "start_date": "2014-02",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-02-15",
      "last_synced_at": "2026-09-29T03:55:12.345Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02354365"
    },
    {
      "nct_id": "NCT02179840",
      "title": "Assessment of Cerebral Microvascular Circulation",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cerebral Microvascular Circulation"
      ],
      "interventions": [
        {
          "name": "Mechanical ventilation adjustment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2015-03",
      "completion_date": "2016-03",
      "has_results": false,
      "last_update_posted_date": "2019-01-08",
      "last_synced_at": "2026-09-29T03:55:12.345Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02179840"
    },
    {
      "nct_id": "NCT04452188",
      "title": "Targeting Normoxia in Neonates With Cyanotic Congenital Heart Disease in the Intra-operative and Immediate Post-operative Period",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypoplastic Left Heart Syndrome",
        "Total Anomalous Pulmonary Venous Return",
        "Truncus Arteriosus",
        "Pulmonary Atresia With Ventricular Septal Defect",
        "Transposition of the Great Arteries",
        "Double Outlet Right Ventricle, Subpulmonary VSD",
        "Tetralogy of Fallot",
        "Double Outlet Right Ventricle With Subaortic Ventricular Septal Defect and Pulmonary Stenosis",
        "Cardiopulmonary Bypass"
      ],
      "interventions": [
        {
          "name": "Normoxia (with controlled re-oxygenation)",
          "type": "OTHER"
        },
        {
          "name": "Standard of care ventilation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "29 Days",
        "sex": "ALL",
        "summary": "Up to 29 Days"
      },
      "enrollment_count": 29,
      "start_date": "2021-01-18",
      "completion_date": "2023-04-20",
      "has_results": true,
      "last_update_posted_date": "2024-06-18",
      "last_synced_at": "2026-09-29T03:55:12.345Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04452188"
    },
    {
      "nct_id": "NCT04821453",
      "title": "NAVA vs. CMV Crossover in Severe BPD",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bronchopulmonary Dysplasia",
        "Neurally Adjusted Ventilatory Assist",
        "Mechanical Ventilation"
      ],
      "interventions": [
        {
          "name": "NAVA",
          "type": "DEVICE"
        },
        {
          "name": "CMV",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "24 Months",
        "sex": "ALL",
        "summary": "Up to 24 Months"
      },
      "enrollment_count": 12,
      "start_date": "2021-09-13",
      "completion_date": "2025-02-28",
      "has_results": true,
      "last_update_posted_date": "2026-05-20",
      "last_synced_at": "2026-09-29T03:55:12.345Z",
      "location_count": 2,
      "location_summary": "Philadelphia, Pennsylvania • Providence, Rhode Island",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04821453"
    }
  ]
}