{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Medication+Optimization&page=5", "query": { "intervention": "Medication Optimization", "page": 5 }, "page_size": 10 }, "pagination": { "page": 5, "page_size": 10, "total_count": 206, "total_pages": 21, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Medication+Optimization&page=6&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Medication+Optimization&page=4&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-22T04:33:20.598Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07148999", "title": "An Advanced Decision Support Tool for Personalized Medicine for IVF Using Modeling and Optimization for Provera", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Infertility (IVF Patients)" ], "interventions": [ { "name": "Opt-IVF", "type": "COMBINATION_PRODUCT" }, { "name": "Control", "type": "OTHER" } ], "intervention_types": [ "COMBINATION_PRODUCT", "OTHER" ], "sponsor": "Urmila DIwekar", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "20 Years", "maximum_age": "50 Years", "sex": "FEMALE", "summary": "20 Years to 50 Years · Female only" }, "enrollment_count": 200, "start_date": "2025-09-23", "completion_date": "2026-02-15", "has_results": false, "last_update_posted_date": "2025-09-29", "last_synced_at": "2026-10-22T04:33:20.598Z", "location_count": 2, "location_summary": "Houston, Texas • San Antonio, Texas", "locations": [ { "city": "Houston", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07148999" }, { "nct_id": "NCT04606264", "title": "Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Perioperative Optimization" ], "interventions": [ { "name": "Neuraxial Analgesia", "type": "DRUG" }, { "name": "Regional Block 1: Paravertebral", "type": "DRUG" }, { "name": "Perphenazine", "type": "DRUG" }, { "name": "Aprepitant", "type": "DRUG" }, { "name": "Dimenhydrinate", "type": "DRUG" }, { "name": "Ondansetron 4 MG", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Regional Block 2: QL1", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Jennifer Holder-Murray", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3395, "start_date": "2023-05-15", "completion_date": "2025-03-21", "has_results": true, "last_update_posted_date": "2026-05-28", "last_synced_at": "2026-10-22T04:33:20.598Z", "location_count": 3, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" }, { "city": "Pittsburgh", "state": "Pennsylvania" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT04606264" }, { "nct_id": "NCT02481219", "title": "Optimization of the Bowel Preparation Regimen for the PillCam® COLON 2 Capsule Endoscopy Procedure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Colorectal Cancer Screening" ], "interventions": [ { "name": "PillCam® COLON 2 procedure-CONTROL", "type": "DEVICE" }, { "name": "Senna tablets", "type": "DRUG" }, { "name": "PEG", "type": "DRUG" }, { "name": "Metoclopramide", "type": "DRUG" }, { "name": "Erythromycin", "type": "DRUG" }, { "name": "SUPREP oral sulfate solution", "type": "DRUG" }, { "name": "Bisacodyl", "type": "DRUG" }, { "name": "SUPREP oral sulfate solution with Gastrografin", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "Medtronic - MITG", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "50 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "50 Years to 75 Years" }, "enrollment_count": 122, "start_date": "2015-05", "completion_date": "2016-02", "has_results": true, "last_update_posted_date": "2017-03-07", "last_synced_at": "2026-10-22T04:33:20.598Z", "location_count": 6, "location_summary": "Anniston, Alabama • Indianapolis, Indiana • Dayton, Ohio + 2 more", "locations": [ { "city": "Anniston", "state": "Alabama" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Dayton", "state": "Ohio" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02481219" }, { "nct_id": "NCT07070232", "title": "A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Advanced Solid Tumor" ], "interventions": [ { "name": "BNT326", "type": "DRUG" }, { "name": "Pumitamig", "type": "DRUG" }, { "name": "Itraconazole", "type": "DRUG" }, { "name": "Paroxetine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "BioNTech SE", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1438, "start_date": "2025-08-12", "completion_date": "2030-03", "has_results": false, "last_update_posted_date": "2026-10-09", "last_synced_at": "2026-10-22T04:33:20.598Z", "location_count": 19, "location_summary": "Phoenix, Arizona • San Francisco, California • Hartford, Connecticut + 15 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "San Francisco", "state": "California" }, { "city": "Hartford", "state": "Connecticut" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Sarasota", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07070232" }, { "nct_id": "NCT02307656", "title": "Taste Properties of Atazanavir and Cobicistat", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "HIV in Adults" ], "interventions": [ { "name": "Atazanavir", "type": "DRUG" }, { "name": "Cobicistat", "type": "DRUG" }, { "name": "Active Pharmaceutical Ingredient", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 6, "start_date": "2014-12-12", "completion_date": "2021-09-09", "has_results": false, "last_update_posted_date": "2022-01-05", "last_synced_at": "2026-10-22T04:33:20.598Z", "location_count": 1, "location_summary": "Woburn, Massachusetts", "locations": [ { "city": "Woburn", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02307656" }, { "nct_id": "NCT04110080", "title": "Enhanced Recovery After Surgery in Kidney Transplant Donors", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Opioid Use", "Kidney Diseases", "Pain, Postoperative", "Postoperative Complications", "Postoperative Nausea and Vomiting" ], "interventions": [ { "name": "multimodal pain management", "type": "PROCEDURE" }, { "name": "goal directed fluid management", "type": "OTHER" }, { "name": "preoperative carbohydrate loading", "type": "OTHER" }, { "name": "Donor nephrectomy", "type": "PROCEDURE" }, { "name": "regional anesthesia", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE", "OTHER" ], "sponsor": "Thomas Jefferson University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 42, "start_date": "2019-09-12", "completion_date": "2023-06-12", "has_results": false, "last_update_posted_date": "2023-04-18", "last_synced_at": "2026-10-22T04:33:20.598Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT04110080" }, { "nct_id": "NCT04257071", "title": "Out of Pocket Cost Communication in Multiple Sclerosis Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Multiple Sclerosis" ], "interventions": [ { "name": "Usual Care", "type": "BEHAVIORAL" }, { "name": "OOP Cost Communication and Optimization", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 61, "start_date": "2020-03-03", "completion_date": "2021-12-31", "has_results": false, "last_update_posted_date": "2022-02-18", "last_synced_at": "2026-10-22T04:33:20.598Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT04257071" }, { "nct_id": "NCT07604571", "title": "Study of IEV407 as Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Advanced HR+/HER2- Breast Cancer" ], "interventions": [ { "name": "IEV407", "type": "DRUG" }, { "name": "Fulvestrant", "type": "DRUG" }, { "name": "Letrozole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 194, "start_date": "2026-05-28", "completion_date": "2032-06-08", "has_results": false, "last_update_posted_date": "2026-10-20", "last_synced_at": "2026-10-22T04:33:20.598Z", "location_count": 3, "location_summary": "New Haven, Connecticut • Kansas City, Kansas • Dallas, Texas", "locations": [ { "city": "New Haven", "state": "Connecticut" }, { "city": "Kansas City", "state": "Kansas" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07604571" }, { "nct_id": "NCT07856082", "title": "Opt-IVF for Personalized Medicine for Normal Responders", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Ivf" ], "interventions": [ { "name": "Opt-IVF", "type": "DEVICE" }, { "name": "control", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "Urmila DIwekar", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "20 Years", "maximum_age": "50 Years", "sex": "FEMALE", "summary": "20 Years to 50 Years · Female only" }, "enrollment_count": 100, "start_date": "2026-10-15", "completion_date": "2027-04-30", "has_results": false, "last_update_posted_date": "2026-10-02", "last_synced_at": "2026-10-22T04:33:20.598Z", "location_count": 1, "location_summary": "West Palm Beach, Florida", "locations": [ { "city": "West Palm Beach", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07856082" }, { "nct_id": "NCT05858320", "title": "The Impact of an Adaptive Patient-centered Web Application on Medication Optimization in HFrEF Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Heart Failure" ], "interventions": [ { "name": "SmartHF application", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 225, "start_date": "2023-07-21", "completion_date": "2025-12-01", "has_results": false, "last_update_posted_date": "2026-01-16", "last_synced_at": "2026-10-22T04:33:20.598Z", "location_count": 5, "location_summary": "Atlanta, Georgia • Ann Arbor, Michigan • Detroit, Michigan + 2 more", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Ypsilanti", "state": "Michigan" }, { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT05858320" } ] }