{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Merlin", "query": { "intervention": "Merlin" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-07T05:51:26.848Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03192306", "title": "Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for Episodic Treatment of Cold Sores", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Recurrent Herpes Labialis" ], "interventions": [ { "name": "Merlin", "type": "DRUG" }, { "name": "Ethanol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Topical Remedy", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 451, "start_date": "2017-07-05", "completion_date": "2018-04-02", "has_results": true, "last_update_posted_date": "2018-09-12", "last_synced_at": "2026-09-07T05:51:26.848Z", "location_count": 6, "location_summary": "Huntsville, Alabama • San Diego, California • Melbourne, Florida + 3 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "San Diego", "state": "California" }, { "city": "Melbourne", "state": "Florida" }, { "city": "Peoria", "state": "Illinois" }, { "city": "Rockville", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03192306" }, { "nct_id": "NCT04702997", "title": "A Trial of Bardoxolone Methyl in Patients With CKD at Risk of Rapid Progression (MERLIN)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Kidney Diseases" ], "interventions": [ { "name": "Bardoxolone methyl oral capsule", "type": "DRUG" }, { "name": "Placebo oral capsule", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biogen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 81, "start_date": "2021-02-09", "completion_date": "2021-11-23", "has_results": true, "last_update_posted_date": "2025-06-03", "last_synced_at": "2026-09-07T05:51:26.848Z", "location_count": 12, "location_summary": "La Mesa, California • Arvada, Colorado • Denver, Colorado + 9 more", "locations": [ { "city": "La Mesa", "state": "California" }, { "city": "Arvada", "state": "Colorado" }, { "city": "Denver", "state": "Colorado" }, { "city": "Nampa", "state": "Idaho" }, { "city": "Baton Rouge", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT04702997" }, { "nct_id": "NCT04759781", "title": "MElanoma Research Lymph Node Prediction Implementation National_001", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Melanoma" ], "interventions": [], "intervention_types": [], "sponsor": "SkylineDx", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1820, "start_date": "2021-08-25", "completion_date": "2029-06", "has_results": false, "last_update_posted_date": "2026-04-23", "last_synced_at": "2026-09-07T05:51:26.848Z", "location_count": 9, "location_summary": "Tampa, Florida • Atlanta, Georgia • Lexington, Kentucky + 6 more", "locations": [ { "city": "Tampa", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Lexington", "state": "Kentucky" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT04759781" }, { "nct_id": "NCT04818645", "title": "Insertable Cardiac Monitor for Primary Atrial Fibrillation Detection in High-Risk Heart Failure Patients", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Atrial Fibrillation", "Heart Failure" ], "interventions": [ { "name": "ASSERT Insertable Cardiac Monitor", "type": "DEVICE" }, { "name": "Conventional Management and monitoring", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "University of Rochester", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 477, "start_date": "2023-01-31", "completion_date": "2028-07-01", "has_results": false, "last_update_posted_date": "2026-03-23", "last_synced_at": "2026-09-07T05:51:26.848Z", "location_count": 1, "location_summary": "Rochester, New York", "locations": [ { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04818645" }, { "nct_id": "NCT01871090", "title": "Remote Device Interrogation In The Emergency Department", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Heart Disease", "Cardiovascular Disease", "Heart Failure", "Arrhythmias, Cardiac" ], "interventions": [ { "name": "Unpaired remote monitoring transmitter", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Abbott Medical Devices", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 99, "start_date": "2013-09", "completion_date": "2015-07", "has_results": true, "last_update_posted_date": "2019-02-15", "last_synced_at": "2026-09-07T05:51:26.848Z", "location_count": 1, "location_summary": "Zanesville, Ohio", "locations": [ { "city": "Zanesville", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01871090" }, { "nct_id": "NCT03599453", "title": "Chemokine Modulation Therapy and Pembrolizumab in Treating Participants With Metastatic Triple-Negative Breast Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Triple -Negative Breast Cancer", "Estrogen Receptor Negative", "HER2/Neu Negative", "Anatomic Stage IV Breast Cancer AJCC", "Progesterone Receptor Negative" ], "interventions": [ { "name": "Biopsy", "type": "PROCEDURE" }, { "name": "Chemokine Modulation Therapy", "type": "PROCEDURE" }, { "name": "Celecoxib", "type": "DRUG" }, { "name": "Recombinant Interferon Alfa-2b", "type": "BIOLOGICAL" }, { "name": "Rintatolimod", "type": "DRUG" }, { "name": "Pembrolizumab", "type": "BIOLOGICAL" } ], "intervention_types": [ "PROCEDURE", "DRUG", "BIOLOGICAL" ], "sponsor": "Roswell Park Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 8, "start_date": "2019-01-09", "completion_date": "2023-03-21", "has_results": false, "last_update_posted_date": "2023-07-18", "last_synced_at": "2026-09-07T05:51:26.848Z", "location_count": 1, "location_summary": "Buffalo, New York", "locations": [ { "city": "Buffalo", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03599453" }, { "nct_id": "NCT01024946", "title": "Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict Sensitivity", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Malignant Pleural Mesothelioma" ], "interventions": [ { "name": "everolimus", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 11, "start_date": "2009-12", "completion_date": "2012-07", "has_results": true, "last_update_posted_date": "2015-05-12", "last_synced_at": "2026-09-07T05:51:26.848Z", "location_count": 3, "location_summary": "Boston, Massachusetts • New York, New York • Philadelphia, Pennsylvania", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "New York", "state": "New York" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01024946" }, { "nct_id": "NCT02421549", "title": "Remote Interrogation in Rural Emergency Departments", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Heart Disease", "Cardiovascular Disease", "Heart Failure", "Arrhythmias, Cardiac" ], "interventions": [ { "name": "Unpaired remote monitoring transmitter", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Abbott Medical Devices", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2014-12", "completion_date": "2016-01", "has_results": false, "last_update_posted_date": "2019-02-04", "last_synced_at": "2026-09-07T05:51:26.848Z", "location_count": 1, "location_summary": "Albuquerque, New Mexico", "locations": [ { "city": "Albuquerque", "state": "New Mexico" } ], "official_url": "https://clinicaltrials.gov/study/NCT02421549" }, { "nct_id": "NCT01985321", "title": "Safety and Efficacy of Merlin (Ethanol and Glycolic Acid Mixture) for the Treatment of Cold Sores", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Recurrent Herpes Labialis" ], "interventions": [ { "name": "ethanol/glycolic acid solution", "type": "DRUG" }, { "name": "Placebo/Ethanol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Topical Remedy", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 469, "start_date": "2013-11", "completion_date": "2014-07", "has_results": true, "last_update_posted_date": "2015-07-16", "last_synced_at": "2026-09-07T05:51:26.848Z", "location_count": 8, "location_summary": "Santa Rosa, California • Pinellas Park, Florida • Chicago, Illinois + 5 more", "locations": [ { "city": "Santa Rosa", "state": "California" }, { "city": "Pinellas Park", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Edina", "state": "Minnesota" }, { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT01985321" }, { "nct_id": "NCT03710564", "title": "Study of Safety and Efficacy of Brolucizumab 6 mg Dosed Every 4 Weeks Compared to Aflibercept 2 mg Dosed Every 4 Weeks in Patients With Retinal Fluid Despite Frequent Anti-VEGF Injections", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Age-Related Macular Degeneration" ], "interventions": [ { "name": "Brolucizumab", "type": "BIOLOGICAL" }, { "name": "Aflibercept", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 535, "start_date": "2018-10-30", "completion_date": "2021-07-01", "has_results": true, "last_update_posted_date": "2023-01-30", "last_synced_at": "2026-09-07T05:51:26.848Z", "location_count": 60, "location_summary": "Phoenix, Arizona • Beverly Hills, California • Huntington Beach, California + 51 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Huntington Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03710564" } ] }