{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Meropenem+Placebo", "query": { "intervention": "Meropenem Placebo" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 12, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Meropenem+Placebo&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-02T20:46:24.754Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03217136", "title": "MK-7625A Plus Metronidazole Versus Meropenem in Pediatric Participants With Complicated Intra-Abdominal Infection (cIAI) (MK-7625A-035)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Complicated Intra-Abdominal Infection" ], "interventions": [ { "name": "Ceftolozane/Tazobactam", "type": "DRUG" }, { "name": "Metronidazole", "type": "DRUG" }, { "name": "Meropenem", "type": "DRUG" }, { "name": "Placebo for Metronidazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Merck Sharp & Dohme LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Days", "maximum_age": "17 Years", "sex": "ALL", "summary": "7 Days to 17 Years" }, "enrollment_count": 94, "start_date": "2018-04-03", "completion_date": "2020-03-16", "has_results": true, "last_update_posted_date": "2023-05-06", "last_synced_at": "2026-09-02T20:46:24.754Z", "location_count": 9, "location_summary": "Los Angeles, California • Orange, California • San Diego, California + 6 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT03217136" }, { "nct_id": "NCT01381562", "title": "GSK2251052 in the Treatment of Complicated Intra-abdominal Infections", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Infections, Intestinal" ], "interventions": [ { "name": "Drug: GSK2251052", "type": "DRUG" }, { "name": "Meropenem", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 15, "start_date": "2011-10-03", "completion_date": "2012-03-05", "has_results": true, "last_update_posted_date": "2017-11-29", "last_synced_at": "2026-09-02T20:46:24.754Z", "location_count": 12, "location_summary": "Mobile, Alabama • Long Beach, California • Torrance, California + 9 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Long Beach", "state": "California" }, { "city": "Torrance", "state": "California" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Council Bluffs", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT01381562" }, { "nct_id": "NCT00061438", "title": "A Study to Determine if Antibiotics Prevent Infection in the Pancreas of Patients Where Part of the Pancreas Has Died", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Pancreatitis, Acute Necrotizing" ], "interventions": [ { "name": "meropenem", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 240, "start_date": "2003-02", "completion_date": "2004-12", "has_results": false, "last_update_posted_date": "2017-09-01", "last_synced_at": "2026-09-02T20:46:24.754Z", "location_count": 9, "location_summary": "San Francisco, California • Tampa, Florida • Chicago, Illinois + 6 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Tampa", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00061438" }, { "nct_id": "NCT02784704", "title": "Efficacy and Safety Study of Eravacycline Compared With Meropenem in Complicated Intra-abdominal Infections", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Complicated Intra-abdominal Infections", "Complicated Appendicitis" ], "interventions": [ { "name": "Eravacycline", "type": "DRUG" }, { "name": "Meropenem", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Tetraphase Pharmaceuticals, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 500, "start_date": "2016-10-13", "completion_date": "2017-05-19", "has_results": true, "last_update_posted_date": "2022-01-06", "last_synced_at": "2026-09-02T20:46:24.754Z", "location_count": 6, "location_summary": "Los Angeles, California • Indianapolis, Indiana • Las Vegas, Nevada + 3 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Las Vegas", "state": "Nevada" }, { "city": "Somers Point", "state": "New Jersey" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02784704" }, { "nct_id": "NCT01147640", "title": "Safety and Efficacy Study to Compare IV CXA 101/Tazobactam and Metronidazole With Meropenem in Complicated Intraabdominal Infections", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Complicated Intra-abdominal Infection" ], "interventions": [ { "name": "CXA-101/ tazobactam and metronidazole", "type": "DRUG" }, { "name": "meropenem plus saline placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 122, "start_date": "2010-06-25", "completion_date": "2011-03-25", "has_results": true, "last_update_posted_date": "2018-10-25", "last_synced_at": "2026-09-02T20:46:24.754Z", "location_count": 11, "location_summary": "Orange, California • Torrance, California • Aurora, Colorado + 8 more", "locations": [ { "city": "Orange", "state": "California" }, { "city": "Torrance", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Newark", "state": "Delaware" }, { "city": "Pensacola", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01147640" }, { "nct_id": "NCT01597973", "title": "Trial for the Treatment of Extensively Drug-Resistant Gram-negative Bacilli (OVERCOME)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pneumonia", "Blood Stream Infection" ], "interventions": [ { "name": "colistin and meropenem", "type": "DRUG" }, { "name": "colistin and placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "95 Years", "sex": "ALL", "summary": "18 Years to 95 Years" }, "enrollment_count": 467, "start_date": "2012-10-06", "completion_date": "2020-08-09", "has_results": true, "last_update_posted_date": "2022-11-14", "last_synced_at": "2026-09-02T20:46:24.754Z", "location_count": 6, "location_summary": "Miami, Florida • Detroit, Michigan • Royal Oak, Michigan + 2 more", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Royal Oak", "state": "Michigan" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01597973" }, { "nct_id": "NCT02972255", "title": "A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of RO7079901 and the Combination of RO7079901 With Meropenem in Adult Healthy Volunteers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy Volunteers" ], "interventions": [ { "name": "RO7079901", "type": "DRUG" }, { "name": "Meropenem", "type": "DRUG" }, { "name": "RO7049389 Placebo", "type": "OTHER" }, { "name": "Meropenem Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Hoffmann-La Roche", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 46, "start_date": "2016-10-31", "completion_date": "2017-03-24", "has_results": false, "last_update_posted_date": "2017-05-19", "last_synced_at": "2026-09-02T20:46:24.754Z", "location_count": 2, "location_summary": "Evansville, Indiana • Madison, Wisconsin", "locations": [ { "city": "Evansville", "state": "Indiana" }, { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT02972255" }, { "nct_id": "NCT03564158", "title": "Evaluate Effects of Meropenem-Vaborbactam on QT/QTc in Healthy Volunteers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "meropenem-vaborbactam", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Moxifloxacin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Rempex (a wholly owned subsidiary of Melinta Therapeutics, Inc.)", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 53, "start_date": "2018-05-01", "completion_date": "2018-11-19", "has_results": false, "last_update_posted_date": "2019-01-10", "last_synced_at": "2026-09-02T20:46:24.754Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03564158" }, { "nct_id": "NCT05226923", "title": "Study of the Safety and Pharmacokinetics of KSP-1007 Alone and Coadministered With Meropenem in Healthy Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Bacterial Infections" ], "interventions": [ { "name": "KSP-1007", "type": "DRUG" }, { "name": "Placebo:0.9% sodium chloride", "type": "OTHER" }, { "name": "Meropenem", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Sumitovant Biopharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 123, "start_date": "2022-01-12", "completion_date": "2022-10-01", "has_results": false, "last_update_posted_date": "2022-10-27", "last_synced_at": "2026-09-02T20:46:24.754Z", "location_count": 1, "location_summary": "Lenexa, Kansas", "locations": [ { "city": "Lenexa", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05226923" }, { "nct_id": "NCT04692181", "title": "SYN-004 Safety and Tolerability in Allo-HCT Subjects", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Acute Graft-Versus-Host Reaction Following Bone Marrow Transplant", "Prevention of CDI in Adult Patients Being Treated With IV Beta-lactam Antibiotics" ], "interventions": [ { "name": "SYN-004, Ribaxamase or Placebo", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Theriva Biologics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 36, "start_date": "2021-02-15", "completion_date": "2030-09-30", "has_results": false, "last_update_posted_date": "2026-03-17", "last_synced_at": "2026-09-02T20:46:24.754Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT04692181" } ] }