{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Method+Comparison&page=28",
    "query": {
      "intervention": "Method Comparison",
      "page": 28
    },
    "page_size": 10
  },
  "pagination": {
    "page": 28,
    "page_size": 10,
    "total_count": 1556,
    "total_pages": 156,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Method+Comparison&page=29&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Method+Comparison&page=27&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-23T17:51:53.826Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07568119",
      "title": "Feasibility and Acceptance of SonoHeal for Airway Clearance and Preliminary Comparison With the Standard of Care",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cystic Fibrosis (CF)",
        "Non Cystic Fibrosis Bronchiectasis",
        "Chronic Obstructive Pulmonary Disease (COPD)"
      ],
      "interventions": [
        {
          "name": "Airway clearance therapy through acoustic oscillations",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cognita Labs LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "11 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2024-02-17",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-10-22",
      "last_synced_at": "2026-10-23T17:51:53.826Z",
      "location_count": 1,
      "location_summary": "Santa Ana, California",
      "locations": [
        {
          "city": "Santa Ana",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07568119"
    },
    {
      "nct_id": "NCT06814587",
      "title": "Hyperpolarized 13C Pyruvate-MRI and FDG-PET in a Single Exam for the Prognosis of Ischemic Cardiomyopathy",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Coronary Artery Disease",
        "Coronary Artery Bypass Graft (CABG)"
      ],
      "interventions": [
        {
          "name": "Hyperpolarized 13C Pyruvate Magnetic Resonance Imaging (HP-13C MRI)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "[¹⁸F]Fluorodeoxyglucose Positron Emission Tomography (FDG-PET)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "SPECT MPI (Single Photon Emission Computed Tomography Myocardial Perfusion Imaging)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "20 Years to 80 Years"
      },
      "enrollment_count": 15,
      "start_date": "2024-07-01",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-14",
      "last_synced_at": "2026-10-23T17:51:53.826Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06814587"
    },
    {
      "nct_id": "NCT02561312",
      "title": "Comparison of Two Methods of Transfusion for Stroke Prevention in Sickle Cell",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anemia, Sickle Cell",
        "Sickling Disorder Due to Hemoglobin S"
      ],
      "interventions": [
        {
          "name": "Rapid manual partial exchange transfusion",
          "type": "OTHER"
        },
        {
          "name": "Simple Transfusion",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Chattanooga-Hamilton County Hospital Authority",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "3 Years to 25 Years"
      },
      "enrollment_count": 9,
      "start_date": "2015-09",
      "completion_date": "2017-09-30",
      "has_results": false,
      "last_update_posted_date": "2018-07-27",
      "last_synced_at": "2026-10-23T17:51:53.826Z",
      "location_count": 1,
      "location_summary": "Chattanooga, Tennessee",
      "locations": [
        {
          "city": "Chattanooga",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02561312"
    },
    {
      "nct_id": "NCT06835439",
      "title": "Development of STEPPT",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain",
        "Back Pain",
        "Low Back Pain",
        "Chronic Pain",
        "Neck Pain"
      ],
      "interventions": [
        {
          "name": "STEPPT Pilot",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Care (Control)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "San Diego State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 144,
      "start_date": "2024-11-02",
      "completion_date": "2025-12-02",
      "has_results": true,
      "last_update_posted_date": "2026-05-11",
      "last_synced_at": "2026-10-23T17:51:53.826Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06835439"
    },
    {
      "nct_id": "NCT03187275",
      "title": "Efficacy of Massage for the Treatment of Cancer-Related Fatigue (CRF) in Prostate Cancer Survivors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer-related Problem/Condition"
      ],
      "interventions": [
        {
          "name": "Swedish Massage Therapy",
          "type": "OTHER"
        },
        {
          "name": "Light Touch Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "45 Years and older · Male only"
      },
      "enrollment_count": 8,
      "start_date": "2018-01-22",
      "completion_date": "2019-03-31",
      "has_results": false,
      "last_update_posted_date": "2019-06-06",
      "last_synced_at": "2026-10-23T17:51:53.826Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03187275"
    },
    {
      "nct_id": "NCT04640311",
      "title": "Comparison of Daprodustat Formulations Produced by Two Methods of Manufacture for Bioequivalence and Dissolution in Healthy Participants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Anaemia"
      ],
      "interventions": [
        {
          "name": "Daprodustat",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 259,
      "start_date": "2020-12-18",
      "completion_date": "2021-05-18",
      "has_results": true,
      "last_update_posted_date": "2025-04-10",
      "last_synced_at": "2026-10-23T17:51:53.826Z",
      "location_count": 4,
      "location_summary": "Anaheim, California • Overland Park, Kansas • Las Vegas, Nevada + 1 more",
      "locations": [
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Overland Park",
          "state": "Kansas"
        },
        {
          "city": "Las Vegas",
          "state": "Nevada"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04640311"
    },
    {
      "nct_id": "NCT03504800",
      "title": "OCT in Diagnosis of Irregular Corneas",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Keratoconus",
        "Corneal Opacity",
        "Corneal Dystrophy"
      ],
      "interventions": [
        {
          "name": "Optical Coherence Tomography",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "14 Years to 85 Years"
      },
      "enrollment_count": 445,
      "start_date": "2018-05-01",
      "completion_date": "2031-02-28",
      "has_results": false,
      "last_update_posted_date": "2025-09-09",
      "last_synced_at": "2026-10-23T17:51:53.826Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03504800"
    },
    {
      "nct_id": "NCT05422131",
      "title": "Clozapine Therapy Sample Collection - Method Comparison Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Patients Prescribed Clozapine"
      ],
      "interventions": [
        {
          "name": "MyCare Insite Clozapine Test",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Saladax Biomedical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 153,
      "start_date": "2022-11-12",
      "completion_date": "2023-05-16",
      "has_results": false,
      "last_update_posted_date": "2023-05-18",
      "last_synced_at": "2026-10-23T17:51:53.826Z",
      "location_count": 1,
      "location_summary": "Bethlehem, Pennsylvania",
      "locations": [
        {
          "city": "Bethlehem",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05422131"
    },
    {
      "nct_id": "NCT05145595",
      "title": "Pain Sensitivity During Puberty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Thermal Sensory Analyzer",
          "type": "DEVICE"
        },
        {
          "name": "Pressure Stimuli",
          "type": "DEVICE"
        },
        {
          "name": "Mechanical Stimuli",
          "type": "DEVICE"
        },
        {
          "name": "Pain Ratings",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Thermal pain thresholds",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pressure pain thresholds (PPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mechanical temporal summation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Conditioned pain modulation (CPM) efficiency",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Offset analgesia efficiency",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cold pain tolerance",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "9 Years to 16 Years"
      },
      "enrollment_count": 36,
      "start_date": "2022-09-20",
      "completion_date": "2024-07-17",
      "has_results": false,
      "last_update_posted_date": "2026-01-09",
      "last_synced_at": "2026-10-23T17:51:53.826Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05145595"
    },
    {
      "nct_id": "NCT04703738",
      "title": "Evaluation of Geistlich Fibro-Gide® in Comparison to CTG for the Treatment Around Implants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Soft Tissue Defect"
      ],
      "interventions": [
        {
          "name": "Soft tissue flap + Connective Tissue Graft",
          "type": "PROCEDURE"
        },
        {
          "name": "Soft tissue flap + Geistlich Fibro-Gide®",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Geistlich Pharma AG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2018-08-13",
      "completion_date": "2026-05-12",
      "has_results": false,
      "last_update_posted_date": "2026-09-09",
      "last_synced_at": "2026-10-23T17:51:53.826Z",
      "location_count": 5,
      "location_summary": "Fullerton, California • Aurora, Colorado • Houston, Texas + 2 more",
      "locations": [
        {
          "city": "Fullerton",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Virginia City",
          "state": "Virginia"
        },
        {
          "city": "Kenosha",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04703738"
    }
  ]
}