{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Method+Comparison&page=58", "query": { "intervention": "Method Comparison", "page": 58 }, "page_size": 10 }, "pagination": { "page": 58, "page_size": 10, "total_count": 1556, "total_pages": 156, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Method+Comparison&page=59&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Method+Comparison&page=57&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-28T00:51:22.493Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05672992", "title": "Longitudinal Spatial Frequency Domain Imaging Study", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Systemic Scleroderma" ], "interventions": [ { "name": "Spatial-frequency domain imaging (SFDI)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Boston University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 78, "start_date": "2023-02-10", "completion_date": "2028-09", "has_results": false, "last_update_posted_date": "2026-01-14", "last_synced_at": "2026-10-28T00:51:22.493Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05672992" }, { "nct_id": "NCT03758807", "title": "A Follow-up Comparison of Active Versus Passive Manual Therapy in Patients With Low Back Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Low Back Pain", "Manual Therapy", "Education" ], "interventions": [ { "name": "Manual Therapy with Traditional Biomechanical Explanation", "type": "OTHER" }, { "name": "Manual Therapy with Neuroplastiicity Explanation", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "St. Ambrose University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 102, "start_date": "2018-06-01", "completion_date": "2018-12-30", "has_results": false, "last_update_posted_date": "2019-04-23", "last_synced_at": "2026-10-28T00:51:22.493Z", "location_count": 1, "location_summary": "Davenport, Iowa", "locations": [ { "city": "Davenport", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT03758807" }, { "nct_id": "NCT03698019", "title": "A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Acral Lentiginous Melanoma", "Clinical Stage III Cutaneous Melanoma AJCC v8", "Clinical Stage IV Cutaneous Melanoma AJCC v8", "Mucosal Melanoma" ], "interventions": [ { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Computed Tomography", "type": "PROCEDURE" }, { "name": "Magnetic Resonance Imaging", "type": "PROCEDURE" }, { "name": "Pembrolizumab", "type": "BIOLOGICAL" }, { "name": "Therapeutic Conventional Surgery", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE", "BIOLOGICAL" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 313, "start_date": "2019-02-15", "completion_date": "2026-10-30", "has_results": true, "last_update_posted_date": "2026-10-26", "last_synced_at": "2026-10-28T00:51:22.493Z", "location_count": 815, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Anchorage, Alaska + 511 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Anchorage", "state": "Alaska" }, { "city": "Anchorage", "state": "Alaska" }, { "city": "Anchorage", "state": "Alaska" } ], "official_url": "https://clinicaltrials.gov/study/NCT03698019" }, { "nct_id": "NCT04310007", "title": "Testing the Addition of the Pill Chemotherapy, Cabozantinib, to the Standard Immune Therapy Nivolumab Compared to Standard Chemotherapy for Non-small Cell Lung Cancer", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Metastatic Lung Non-Squamous Non-Small Cell Carcinoma", "Recurrent Lung Non-Squamous Non-Small Cell Carcinoma", "Stage IV Lung Cancer AJCC v8" ], "interventions": [ { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Cabozantinib S-malate", "type": "DRUG" }, { "name": "Computed Tomography", "type": "PROCEDURE" }, { "name": "Docetaxel", "type": "DRUG" }, { "name": "Echocardiography Test", "type": "PROCEDURE" }, { "name": "Gemcitabine Hydrochloride", "type": "DRUG" }, { "name": "Nab-paclitaxel", "type": "DRUG" }, { "name": "Nivolumab", "type": "BIOLOGICAL" }, { "name": "Paclitaxel", "type": "DRUG" }, { "name": "Ramucirumab", "type": "BIOLOGICAL" } ], "intervention_types": [ "PROCEDURE", "DRUG", "BIOLOGICAL" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 117, "start_date": "2020-07-13", "completion_date": "2027-03-31", "has_results": false, "last_update_posted_date": "2026-10-26", "last_synced_at": "2026-10-28T00:51:22.493Z", "location_count": 611, "location_summary": "Birmingham, Alabama • Anchorage, Alaska • Fairbanks, Alaska + 392 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Anchorage", "state": "Alaska" }, { "city": "Anchorage", "state": "Alaska" }, { "city": "Anchorage", "state": "Alaska" }, { "city": "Anchorage", "state": "Alaska" } ], "official_url": "https://clinicaltrials.gov/study/NCT04310007" }, { "nct_id": "NCT02841592", "title": "Non-rebreather at Flush Rate Compared to Bag Valve Mask With Assist", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Acute Respiratory Failure" ], "interventions": [ { "name": "Flush rate oxygen", "type": "OTHER" }, { "name": "Flush rate oxygen with assist", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Hennepin Healthcare Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 27, "start_date": "2016-07", "completion_date": "2016-08", "has_results": false, "last_update_posted_date": "2018-01-30", "last_synced_at": "2026-10-28T00:51:22.493Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT02841592" }, { "nct_id": "NCT07126756", "title": "LASIK iDesign vs SMILE", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Myopia", "Astigmatism" ], "interventions": [ { "name": "STAR S4 IR Excimer Laser System", "type": "DEVICE" }, { "name": "VisuMax 400 Surgical Laser", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "59th Medical Wing", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "21 Years to 50 Years" }, "enrollment_count": 57, "start_date": "2024-06-10", "completion_date": "2026-01-31", "has_results": false, "last_update_posted_date": "2025-08-17", "last_synced_at": "2026-10-28T00:51:22.493Z", "location_count": 1, "location_summary": "Lackland Air Force Base, Texas", "locations": [ { "city": "Lackland Air Force Base", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07126756" }, { "nct_id": "NCT05639556", "title": "Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Cystic Fibrosis" ], "interventions": [ { "name": "BMI and lean mass index from DXA", "type": "DIAGNOSTIC_TEST" }, { "name": "Anthropometric Measurements", "type": "DIAGNOSTIC_TEST" }, { "name": "Hand-grip strength", "type": "DIAGNOSTIC_TEST" }, { "name": "Six-minute walk Test", "type": "DIAGNOSTIC_TEST" }, { "name": "Sit-to-Stand Test", "type": "DIAGNOSTIC_TEST" }, { "name": "Short physical performance battery (SPPB)", "type": "DIAGNOSTIC_TEST" }, { "name": "BIA Sub-study", "type": "DIAGNOSTIC_TEST" }, { "name": "Accelerometry to assess physical activity", "type": "DIAGNOSTIC_TEST" }, { "name": "Gastrointestinal (GI) and nutrition questionnaires:", "type": "OTHER" }, { "name": "Psychosocial questionnaire: PHQ-8", "type": "OTHER" }, { "name": "Psychosocial questionnaire: GAD-7", "type": "OTHER" }, { "name": "Psychosocial questionnaire: The Treatment Self-Regulation Questionnaire (TSRQ)", "type": "OTHER" }, { "name": "Psychosocial questionnaire: CF Fatalism Scale", "type": "OTHER" }, { "name": "Psychosocial questionnaire: Body Esteem Scale for Adolescents and Adults (BESAA)", "type": "OTHER" }, { "name": "12-month Questionnaire", "type": "OTHER" }, { "name": "Oral glucose tolerance testing (OGTT)", "type": "OTHER" }, { "name": "Continuous glucose monitoring (CGM)", "type": "DEVICE" }, { "name": "Chest CT scans (When available within the past 6 months in medical records)", "type": "DIAGNOSTIC_TEST" }, { "name": "Hologic Dual X-Ray Absorptiometry (DXA)", "type": "DIAGNOSTIC_TEST" }, { "name": "Ultrasound Sub-study of assessment of appendage muscles using ultrasound", "type": "DIAGNOSTIC_TEST" }, { "name": "Psychosocial questionnaire: Hunger Vital Sign questionnaire", "type": "DIAGNOSTIC_TEST" }, { "name": "Respiratory symptom questionnaire: CRISS", "type": "OTHER" }, { "name": "Spirometry", "type": "DIAGNOSTIC_TEST" }, { "name": "Psychosocial questionnaire: Additional Health Questionnaire", "type": "OTHER" }, { "name": "CF Management Questionnaire", "type": "OTHER" }, { "name": "Food Frequency Questionnaire", "type": "OTHER" } ], "intervention_types": [ "DIAGNOSTIC_TEST", "OTHER", "DEVICE" ], "sponsor": "Jaeb Center for Health Research", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 300, "start_date": "2023-04-20", "completion_date": "2028-12", "has_results": false, "last_update_posted_date": "2026-03-13", "last_synced_at": "2026-10-28T00:51:22.493Z", "location_count": 23, "location_summary": "Tucson, Arizona • Little Rock, Arkansas • Atlanta, Georgia + 19 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT05639556" }, { "nct_id": "NCT02056288", "title": "A Comparison of UGSB and GA to IV Narcotics and GA for Post-Op Pain in Children With Supracondylar Fractures.", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Supracondylar Fractures" ], "interventions": [ { "name": "Fentanyl", "type": "DRUG" }, { "name": "Ropivacaine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Baylor College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "2 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "2 Years to 17 Years" }, "enrollment_count": 78, "start_date": "2011-03-10", "completion_date": "2019-03-01", "has_results": true, "last_update_posted_date": "2021-05-21", "last_synced_at": "2026-10-28T00:51:22.493Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02056288" }, { "nct_id": "NCT05495841", "title": "OPTiMASK: Comparison of Pre-oxygenation With Standard Face Mask Combined With High Flow Nasal Oxygen With Pre-oxygenation With Standard Face Mask Alone", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Surgery" ], "interventions": [ { "name": "Pre-oxygenation", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Beth Israel Deaconess Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 80, "start_date": "2022-08-18", "completion_date": "2023-06-30", "has_results": false, "last_update_posted_date": "2023-11-30", "last_synced_at": "2026-10-28T00:51:22.493Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05495841" }, { "nct_id": "NCT05112601", "title": "Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Endometrial Adenocarcinoma", "Endometrial Clear Cell Adenocarcinoma", "Endometrial Dedifferentiated Carcinoma", "Endometrial Endometrioid Adenocarcinoma", "Endometrial Mixed Cell Adenocarcinoma", "Endometrial Mucinous Adenocarcinoma", "Endometrial Undifferentiated Carcinoma", "Endometrioid Adenocarcinoma", "Recurrent Endometrial Carcinoma" ], "interventions": [ { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Computed Tomography", "type": "PROCEDURE" }, { "name": "Ipilimumab", "type": "BIOLOGICAL" }, { "name": "Magnetic Resonance Imaging", "type": "PROCEDURE" }, { "name": "Nivolumab", "type": "BIOLOGICAL" } ], "intervention_types": [ "PROCEDURE", "BIOLOGICAL" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 81, "start_date": "2022-06-02", "completion_date": "2032-07-30", "has_results": false, "last_update_posted_date": "2026-10-21", "last_synced_at": "2026-10-28T00:51:22.493Z", "location_count": 138, "location_summary": "Birmingham, Alabama • Athens, Georgia • Augusta, Georgia + 107 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Athens", "state": "Georgia" }, { "city": "Augusta", "state": "Georgia" }, { "city": "Boise", "state": "Idaho" }, { "city": "Boise", "state": "Idaho" } ], "official_url": "https://clinicaltrials.gov/study/NCT05112601" } ] }