{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Methylene+Blue+%2B+Chlorhexidine+Gluconate", "query": { "intervention": "Methylene Blue + Chlorhexidine Gluconate" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 11, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Methylene+Blue+%2B+Chlorhexidine+Gluconate&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-30T17:09:56.190Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06702878", "title": "Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Surgical Site Infections", "Surgical Wound Infection", "Infections", "Anti-Infective Agents" ], "interventions": [ { "name": "nasal antimicrobial photodisinfection therapy", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT" ], "sponsor": "Ondine Biomedical Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 4787, "start_date": "2024-12-27", "completion_date": "2026-05-07", "has_results": false, "last_update_posted_date": "2026-09-15", "last_synced_at": "2026-09-30T17:09:56.190Z", "location_count": 14, "location_summary": "Englewood, Colorado • Brandon, Florida • Largo, Florida + 9 more", "locations": [ { "city": "Englewood", "state": "Colorado" }, { "city": "Brandon", "state": "Florida" }, { "city": "Largo", "state": "Florida" }, { "city": "St. Petersburg", "state": "Florida" }, { "city": "Trinity", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06702878" }, { "nct_id": "NCT05797818", "title": "Red Light Photobiomodulation and Topical Disinfectants", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Healthcare Associated Infection", "Nosocomial Infection", "Surgical Site Infection" ], "interventions": [ { "name": "Methylene Blue Only", "type": "DEVICE" }, { "name": "Chlorhexidine Gluconate Only", "type": "DEVICE" }, { "name": "Methylene Blue + Chlorhexidine Gluconate", "type": "DEVICE" }, { "name": "Light Only", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Ondine Biomedical Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 28, "start_date": "2023-01-10", "completion_date": "2023-02-08", "has_results": false, "last_update_posted_date": "2023-04-04", "last_synced_at": "2026-09-30T17:09:56.190Z", "location_count": 1, "location_summary": "Bothell, Washington", "locations": [ { "city": "Bothell", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT05797818" }, { "nct_id": "NCT02578771", "title": "Pilot Clinical Evaluation to Characterize in Vivo Effects of Topically Applied ZuraPrep & ZuraPrep Vehicle", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Surgical Site Infection" ], "interventions": [ { "name": "ZuraPrep with 70% IPA", "type": "DRUG" }, { "name": "ZuraPrep without 70% IPA", "type": "DRUG" }, { "name": "ChloraPrep CHG/IPA Teal Tint", "type": "DRUG" }, { "name": "Normal Saline", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Zurex Pharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 123, "start_date": "2015-10", "completion_date": "2016-01", "has_results": false, "last_update_posted_date": "2017-07-17", "last_synced_at": "2026-09-30T17:09:56.190Z", "location_count": 1, "location_summary": "Sterling, Virginia", "locations": [ { "city": "Sterling", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02578771" }, { "nct_id": "NCT03782103", "title": "In-vivo Efficacy of Patient Preoperative Prep, ZuraPrep (ZP)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Surgical Skin Preparation" ], "interventions": [ { "name": "ZuraPrep Clear Solution", "type": "DRUG" }, { "name": "ChloraPrep", "type": "DRUG" }, { "name": "ZuraPrep Vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Zurex Pharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 156, "start_date": "2019-01-25", "completion_date": "2019-09-26", "has_results": true, "last_update_posted_date": "2023-02-08", "last_synced_at": "2026-09-30T17:09:56.190Z", "location_count": 1, "location_summary": "Sterling, Virginia", "locations": [ { "city": "Sterling", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT03782103" }, { "nct_id": "NCT02221232", "title": "Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Surgical Site Infection" ], "interventions": [ { "name": "Chloraprep", "type": "DRUG" }, { "name": "ZuraPrep", "type": "DRUG" }, { "name": "ZuraPrep Vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Zurex Pharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 64, "start_date": "2014-08", "completion_date": "2014-10", "has_results": false, "last_update_posted_date": "2016-07-18", "last_synced_at": "2026-09-30T17:09:56.190Z", "location_count": 1, "location_summary": "Bozeman, Montana", "locations": [ { "city": "Bozeman", "state": "Montana" } ], "official_url": "https://clinicaltrials.gov/study/NCT02221232" }, { "nct_id": "NCT02831998", "title": "In-vivo Efficacy of Patient Preoperative Prep", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Surgical Skin Preparation" ], "interventions": [ { "name": "ZuraPrep", "type": "DRUG" }, { "name": "ChloraPrep", "type": "DRUG" }, { "name": "ZP Vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Zurex Pharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 440, "start_date": "2016-07-27", "completion_date": "2017-04-09", "has_results": true, "last_update_posted_date": "2023-02-08", "last_synced_at": "2026-09-30T17:09:56.190Z", "location_count": 1, "location_summary": "Sterling, Virginia", "locations": [ { "city": "Sterling", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02831998" }, { "nct_id": "NCT02160587", "title": "Safety Study to Evaluate the Contact Sensitizing Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Surgical Site Infection" ], "interventions": [ { "name": "Chloraprep", "type": "DRUG" }, { "name": "0.9% Physiological Saline", "type": "DRUG" }, { "name": "ZuraPrep without IPA", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Zurex Pharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 208, "start_date": "2014-07", "completion_date": "2014-10", "has_results": false, "last_update_posted_date": "2015-03-17", "last_synced_at": "2026-09-30T17:09:56.190Z", "location_count": 1, "location_summary": "Bozeman, Montana", "locations": [ { "city": "Bozeman", "state": "Montana" } ], "official_url": "https://clinicaltrials.gov/study/NCT02160587" }, { "nct_id": "NCT02831816", "title": "Clinical Evaluation of Patient Preoperative Prep", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Surgical Skin Preparation" ], "interventions": [ { "name": "ZuraPrep", "type": "DRUG" }, { "name": "ChloraPrep", "type": "DRUG" }, { "name": "ZP Vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Zurex Pharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 640, "start_date": "2016-08-03", "completion_date": "2017-08-03", "has_results": true, "last_update_posted_date": "2021-07-16", "last_synced_at": "2026-09-30T17:09:56.190Z", "location_count": 1, "location_summary": "Bozeman, Montana", "locations": [ { "city": "Bozeman", "state": "Montana" } ], "official_url": "https://clinicaltrials.gov/study/NCT02831816" }, { "nct_id": "NCT05090657", "title": "Nasal Photodisinfection in All Patients Presenting for Surgery for a Wide Range of Surgical Procedures", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Surgical Site Infections", "Nosocomial Infection", "Healthcare Associated Infections" ], "interventions": [ { "name": "methylene blue 0.01%/chlorhexidine gluconate 0.25% + light activation", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT" ], "sponsor": "Ondine Biomedical Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 322, "start_date": "2022-02-04", "completion_date": "2022-08-06", "has_results": false, "last_update_posted_date": "2022-08-22", "last_synced_at": "2026-09-30T17:09:56.190Z", "location_count": 1, "location_summary": "Savannah, Georgia", "locations": [ { "city": "Savannah", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT05090657" }, { "nct_id": "NCT02160574", "title": "Safety Study to Evaluate the Cumulative Irritation Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Surgical Site Infection" ], "interventions": [ { "name": "ChloraPrep", "type": "DRUG" }, { "name": "0.1% Sodium Lauryl Sulfate", "type": "DRUG" }, { "name": "0.9% Physiological Saline", "type": "DRUG" }, { "name": "ZuraPrep without IPA", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Zurex Pharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2014-06", "completion_date": "2014-09", "has_results": false, "last_update_posted_date": "2014-10-27", "last_synced_at": "2026-09-30T17:09:56.190Z", "location_count": 1, "location_summary": "Bozeman, Montana", "locations": [ { "city": "Bozeman", "state": "Montana" } ], "official_url": "https://clinicaltrials.gov/study/NCT02160574" } ] }