{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Methylphenidate+Hydrochloride+20+mg", "query": { "intervention": "Methylphenidate Hydrochloride 20 mg" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 50, "total_pages": 5, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Methylphenidate+Hydrochloride+20+mg&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-26T10:10:41.156Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00586157", "title": "Study of Medication Patch to Treat Children Ages 6-12 With ADHD", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "ADHD", "Attention Deficit Hyperactivity Disorder" ], "interventions": [ { "name": "Methylphenidate Transdermal System", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "12 Years", "sex": "ALL", "summary": "6 Years to 12 Years" }, "enrollment_count": 36, "start_date": "2006-09", "completion_date": "2008-12", "has_results": true, "last_update_posted_date": "2012-11-16", "last_synced_at": "2026-09-26T10:10:41.156Z", "location_count": 1, "location_summary": "Cambridge, Massachusetts", "locations": [ { "city": "Cambridge", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00586157" }, { "nct_id": "NCT02493777", "title": "A Pivotal Efficacy Trial to Evaluate HLD200 in Children With ADHD in a Classroom Setting", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Attention Deficit Hyperactivity Disorder" ], "interventions": [ { "name": "HLD200 methylphenidate hydrochloride (MPH) Capsules", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ironshore Pharmaceuticals and Development, Inc", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "12 Years", "sex": "ALL", "summary": "6 Years to 12 Years" }, "enrollment_count": 125, "start_date": "2015-07", "completion_date": "2016-03", "has_results": true, "last_update_posted_date": "2021-07-23", "last_synced_at": "2026-09-26T10:10:41.156Z", "location_count": 7, "location_summary": "Newport Beach, California • Bradenton, Florida • Maitland, Florida + 4 more", "locations": [ { "city": "Newport Beach", "state": "California" }, { "city": "Bradenton", "state": "Florida" }, { "city": "Maitland", "state": "Florida" }, { "city": "Marshfield", "state": "Massachusetts" }, { "city": "Las Vegas", "state": "Nevada" } ], "official_url": "https://clinicaltrials.gov/study/NCT02493777" }, { "nct_id": "NCT00223691", "title": "Treatment of Orthostatic Hypotension in Autonomic Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Autonomic Failure", "Orthostatic Hypotension" ], "interventions": [ { "name": "Atomoxetine", "type": "DRUG" }, { "name": "Acarbose", "type": "DRUG" }, { "name": "Pyridostigmine Bromide", "type": "DRUG" }, { "name": "Yohimbine", "type": "DRUG" }, { "name": "Midodrine HCl", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" }, { "name": "Modafinil", "type": "DRUG" }, { "name": "Octreotide", "type": "DRUG" }, { "name": "water intake", "type": "OTHER" }, { "name": "Diphenhydramine Hydrochloride", "type": "DRUG" }, { "name": "Ranitidine HCL", "type": "DRUG" }, { "name": "Tranylcypromine", "type": "DRUG" }, { "name": "Ergotamine/ Caffeine", "type": "DRUG" }, { "name": "Celecoxib", "type": "DRUG" }, { "name": "Pseudoephedrine", "type": "DRUG" }, { "name": "Methylphenidate", "type": "DRUG" }, { "name": "Indomethacin", "type": "DRUG" }, { "name": "Ibuprofen", "type": "DRUG" }, { "name": "Oxymetazoline 0.05% nasal solution", "type": "DRUG" }, { "name": "Bovril", "type": "DIETARY_SUPPLEMENT" }, { "name": "Acetazolamide", "type": "DRUG" }, { "name": "Rivastigmine tartrate", "type": "DRUG" }, { "name": "Carbidopa/levodopa", "type": "DRUG" }, { "name": "Inflatable abdominal binder", "type": "DEVICE" }, { "name": "inflatable abdominal binder (sham)", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "OTHER", "DIETARY_SUPPLEMENT", "DEVICE" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 389, "start_date": "2002-03", "completion_date": "2017-01", "has_results": false, "last_update_posted_date": "2017-01-18", "last_synced_at": "2026-09-26T10:10:41.156Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00223691" }, { "nct_id": "NCT00178503", "title": "Methylphenidate for Attention Deficit Hyperactivity Disorder and Autism in Children", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Autism", "Attention Deficit Disorder With Hyperactivity" ], "interventions": [ { "name": "Methylphenidate-extended release", "type": "DRUG" }, { "name": "Methylphenidate-immediate release", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "The University of Texas Health Science Center, Houston", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "7 Years", "maximum_age": "12 Years", "sex": "ALL", "summary": "7 Years to 12 Years" }, "enrollment_count": 24, "start_date": "2005-09", "completion_date": "2011-05", "has_results": true, "last_update_posted_date": "2013-05-09", "last_synced_at": "2026-09-26T10:10:41.156Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00178503" }, { "nct_id": "NCT07306078", "title": "Methylphenidate and Response to Alcohol Cues", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Alcohol Use Disorder" ], "interventions": [ { "name": "Methylphenidate Pill", "type": "DRUG" }, { "name": "Placebo Pill", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Florida", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "25 Years", "sex": "ALL", "summary": "18 Years to 25 Years" }, "enrollment_count": 50, "start_date": "2026-10", "completion_date": "2028-08", "has_results": false, "last_update_posted_date": "2026-08-20", "last_synced_at": "2026-09-26T10:10:41.156Z", "location_count": 1, "location_summary": "Gainesville, Florida", "locations": [ { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07306078" }, { "nct_id": "NCT00257725", "title": "Long-Duration Stimulant Treatment Study of ADHD in Young Children", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Attention Deficit Disorder With Hyperactivity" ], "interventions": [ { "name": "B-MPH", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "New York State Psychiatric Institute", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "4 Years", "maximum_age": "5 Years", "sex": "ALL", "summary": "4 Years to 5 Years" }, "enrollment_count": 11, "start_date": "2005-03", "completion_date": "2008-03", "has_results": true, "last_update_posted_date": "2020-08-26", "last_synced_at": "2026-09-26T10:10:41.156Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00257725" }, { "nct_id": "NCT02265718", "title": "A Study To Evaluate The Difference In iPad-Based Cognitive Video Game (Akili Interactive's Project: EVO) Performance In Amyloid-Positive Versus Amyloid-Negative Healthy Elderly Volunteers", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Healthy" ], "interventions": [ { "name": "Ritalin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "70 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "70 Years to 80 Years" }, "enrollment_count": 97, "start_date": "2014-09", "completion_date": "2016-05", "has_results": false, "last_update_posted_date": "2019-06-05", "last_synced_at": "2026-09-26T10:10:41.156Z", "location_count": 4, "location_summary": "Long Beach, California • Hollywood, Florida • South Miami, Florida + 1 more", "locations": [ { "city": "Long Beach", "state": "California" }, { "city": "Hollywood", "state": "Florida" }, { "city": "South Miami", "state": "Florida" }, { "city": "Kalamazoo", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT02265718" }, { "nct_id": "NCT00429273", "title": "Single Versus Combination Medication Treatment for Children With Attention Deficit Hyperactivity Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Attention Deficit Disorder With Hyperactivity" ], "interventions": [ { "name": "Guanfacine", "type": "DRUG" }, { "name": "Methylphenidate (MPH)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Years", "maximum_age": "14 Years", "sex": "ALL", "summary": "7 Years to 14 Years" }, "enrollment_count": 212, "start_date": "2007-01", "completion_date": "2011-07", "has_results": true, "last_update_posted_date": "2021-07-30", "last_synced_at": "2026-09-26T10:10:41.156Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00429273" }, { "nct_id": "NCT01416948", "title": "Cognitive REmediation After Trauma Exposure Trial = CREATE Trial", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Posttraumatic Stress Disorder", "Traumatic Brain Injury" ], "interventions": [ { "name": "Methylphenidate Hydrochloride 20 mg", "type": "DRUG" }, { "name": "Placebo Capsule", "type": "DRUG" }, { "name": "Galantamine 12 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 32, "start_date": "2011-08", "completion_date": "2013-03", "has_results": false, "last_update_posted_date": "2013-04-26", "last_synced_at": "2026-09-26T10:10:41.156Z", "location_count": 7, "location_summary": "San Diego, California • Boston, Massachusetts • Manchester, New Hampshire + 4 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Manchester", "state": "New Hampshire" }, { "city": "Durham", "state": "North Carolina" }, { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01416948" }, { "nct_id": "NCT00302393", "title": "Study Examining Repeat Dosing of OROS® Methylphenidate (CONCERTA®) and Immediate Release Methylphenidate in Healthy Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "OROS methylphenidate hydrochloride", "type": "DRUG" }, { "name": "methylphenidate hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 20, "start_date": "2006-06", "completion_date": "2008-02", "has_results": false, "last_update_posted_date": "2013-10-22", "last_synced_at": "2026-09-26T10:10:41.156Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00302393" } ] }