{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Metoprolol+100+mg&page=2", "query": { "intervention": "Metoprolol 100 mg", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 33, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Metoprolol+100+mg&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Metoprolol+100+mg&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-04T03:27:53.630Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01595516", "title": "Nebivolol and Endothelial Regulation of Fibrinolysis (NERF)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Prehypertension", "Hypertension" ], "interventions": [ { "name": "Nebivolol", "type": "DRUG" }, { "name": "Metoprolol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Bradykinin", "type": "OTHER" }, { "name": "Saline", "type": "OTHER" }, { "name": "Vitamin C", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Colorado, Boulder", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "45 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "45 Years to 65 Years" }, "enrollment_count": 44, "start_date": "2012-02", "completion_date": "2017-10", "has_results": true, "last_update_posted_date": "2019-06-25", "last_synced_at": "2026-10-04T03:27:53.630Z", "location_count": 1, "location_summary": "Boulder, Colorado", "locations": [ { "city": "Boulder", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT01595516" }, { "nct_id": "NCT05931276", "title": "CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "End-Stage Kidney Disease", "End-Stage Renal Disease" ], "interventions": [ { "name": "Metoprolol Succinate", "type": "DRUG" }, { "name": "Carvedilol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2540, "start_date": "2024-05-22", "completion_date": "2028-12-31", "has_results": false, "last_update_posted_date": "2026-01-09", "last_synced_at": "2026-10-04T03:27:53.630Z", "location_count": 8, "location_summary": "Long Beach, California • Gainesville, Florida • Decatur, Georgia + 5 more", "locations": [ { "city": "Long Beach", "state": "California" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Decatur", "state": "Georgia" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05931276" }, { "nct_id": "NCT03556592", "title": "Drug-drug Interaction Trial With Tralokinumab in Moderate to Severe Atopic Dermatitis - ECZTRA 4", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Atopic Dermatitis" ], "interventions": [ { "name": "Tralokinumab", "type": "DRUG" }, { "name": "Caffeine", "type": "DRUG" }, { "name": "Warfarin", "type": "DRUG" }, { "name": "Omeprazole", "type": "DRUG" }, { "name": "Metoprolol", "type": "DRUG" }, { "name": "Midazolam Hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "LEO Pharma", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2018-08-13", "completion_date": "2020-06-20", "has_results": false, "last_update_posted_date": "2025-02-24", "last_synced_at": "2026-10-04T03:27:53.630Z", "location_count": 9, "location_summary": "Little Rock, Arkansas • Rogers, Arkansas • San Diego, California + 5 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Rogers", "state": "Arkansas" }, { "city": "San Diego", "state": "California" }, { "city": "Doral", "state": "Florida" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03556592" }, { "nct_id": "NCT00649116", "title": "Fed Study of Metoprolol Tartrate Tablets 100 mg and Lopressor® 100 mg", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Metoprolol Tartrate Tablets 100 mg", "type": "DRUG" }, { "name": "Lopressor® Tablets 100 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Mylan Pharmaceuticals Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2002-12", "completion_date": "2003-01", "has_results": false, "last_update_posted_date": "2024-04-23", "last_synced_at": "2026-10-04T03:27:53.630Z", "location_count": 1, "location_summary": "Morgantown, West Virginia", "locations": [ { "city": "Morgantown", "state": "West Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00649116" }, { "nct_id": "NCT01324388", "title": "A Study of the Effect of LY2189265 on Two Blood Pressure Drugs", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Diabetes Mellitus, Type 2" ], "interventions": [ { "name": "LY2189265", "type": "BIOLOGICAL" }, { "name": "Metoprolol", "type": "DRUG" }, { "name": "Lisinopril", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 51, "start_date": "2011-03", "completion_date": "2011-08", "has_results": true, "last_update_posted_date": "2014-10-08", "last_synced_at": "2026-10-04T03:27:53.630Z", "location_count": 3, "location_summary": "Honolulu, Hawaii • Evansville, Indiana • Dallas, Texas", "locations": [ { "city": "Honolulu", "state": "Hawaii" }, { "city": "Evansville", "state": "Indiana" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01324388" }, { "nct_id": "NCT00246519", "title": "Pharmacogenomic Evaluation of Antihypertensive Responses", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Hydrochlorothiazide", "type": "DRUG" }, { "name": "Atenolol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Florida", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "17 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "17 Years to 65 Years" }, "enrollment_count": 1701, "start_date": "2005-10", "completion_date": "2010-12", "has_results": true, "last_update_posted_date": "2018-05-07", "last_synced_at": "2026-10-04T03:27:53.630Z", "location_count": 3, "location_summary": "Gainesville, Florida • Atlanta, Georgia • Rochester, Minnesota", "locations": [ { "city": "Gainesville", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00246519" }, { "nct_id": "NCT00993421", "title": "A Weight Loss Study in Overweight Men and Women", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Obesity" ], "interventions": [ { "name": "LY377604", "type": "DRUG" }, { "name": "Sibutramine", "type": "DRUG" }, { "name": "Metoprolol", "type": "DRUG" }, { "name": "Placebo sibutramine", "type": "DRUG" }, { "name": "Placebo Metoprolol", "type": "DRUG" }, { "name": "Placebo LY377604", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 343, "start_date": "2009-10", "completion_date": "2010-06", "has_results": true, "last_update_posted_date": "2011-06-03", "last_synced_at": "2026-10-04T03:27:53.630Z", "location_count": 21, "location_summary": "Mesa, Arizona • Concord, California • La Jolla, California + 18 more", "locations": [ { "city": "Mesa", "state": "Arizona" }, { "city": "Concord", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "Waterbury", "state": "Connecticut" }, { "city": "South Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00993421" }, { "nct_id": "NCT04713254", "title": "Drug Drug Interaction Study With Lu AG06466 in Young Healthy Men", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Lu AG06466", "type": "DRUG" }, { "name": "Midazolam", "type": "OTHER" }, { "name": "Metoprolol", "type": "OTHER" }, { "name": "Bupropion", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "H. Lundbeck A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 15, "start_date": "2020-12-08", "completion_date": "2021-04-09", "has_results": false, "last_update_posted_date": "2021-04-20", "last_synced_at": "2026-10-04T03:27:53.630Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04713254" }, { "nct_id": "NCT00223717", "title": "Treatment of Supine Hypertension in Autonomic Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Clonidine", "type": "DRUG" }, { "name": "Nitroglycerin transdermal", "type": "DRUG" }, { "name": "Dipyridamole/ Aspirin (Aggrenox)", "type": "DRUG" }, { "name": "Desmopressin (DDAVP)", "type": "DRUG" }, { "name": "Sildenafil", "type": "DRUG" }, { "name": "Nifedipine", "type": "DRUG" }, { "name": "Hydralazine", "type": "DRUG" }, { "name": "Hydrochlorothiazide", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Bosentan", "type": "DRUG" }, { "name": "Diltiazem", "type": "DRUG" }, { "name": "Eplerenone", "type": "DRUG" }, { "name": "guanfacine", "type": "DRUG" }, { "name": "L-arginine", "type": "DIETARY_SUPPLEMENT" }, { "name": "captopril", "type": "DRUG" }, { "name": "carbidopa", "type": "DRUG" }, { "name": "losartan", "type": "DRUG" }, { "name": "metoprolol tartrate", "type": "DRUG" }, { "name": "nebivolol hydrochloride", "type": "DRUG" }, { "name": "prazosin hydrochloride", "type": "DRUG" }, { "name": "tamsulosin hydrochloride", "type": "DRUG" }, { "name": "Head-up tilt.", "type": "OTHER" }, { "name": "aliskiren", "type": "DRUG" }, { "name": "Local heat stress", "type": "OTHER" } ], "intervention_types": [ "DRUG", "DIETARY_SUPPLEMENT", "OTHER" ], "sponsor": "Vanderbilt University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 152, "start_date": "2001-01", "completion_date": "2017-01", "has_results": false, "last_update_posted_date": "2017-10-13", "last_synced_at": "2026-10-04T03:27:53.630Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00223717" }, { "nct_id": "NCT01052428", "title": "Molecular Mechanisms of Volume Overload-Aim 1(SCCOR in Cardiac Dysfunction and Disease)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Mitral Regurgitation" ], "interventions": [ { "name": "metoprolol succinate (Toprol XL)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Alabama at Birmingham", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "19 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "19 Years to 70 Years" }, "enrollment_count": 38, "start_date": "2004-08", "completion_date": "2010-07", "has_results": true, "last_update_posted_date": "2012-11-22", "last_synced_at": "2026-10-04T03:27:53.630Z", "location_count": 1, "location_summary": "Birmingham, Alabama", "locations": [ { "city": "Birmingham", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT01052428" } ] }