{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Metoprolol+Tartrate+Oral+Tablet", "query": { "intervention": "Metoprolol Tartrate Oral Tablet" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 15, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Metoprolol+Tartrate+Oral+Tablet&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-30T21:04:00.380Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01902550", "title": "A Crossover Study to Evaluate the Effect of JNJ-54452840 on Pharmacodynamics of Metoprolol Tartrate Immediate-Release in Healthy Participants", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Metoprolol tartrate immediate-release (metoprolol IR)", "type": "DRUG" }, { "name": "JNJ-54452840", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "MALE", "summary": "18 Years to 45 Years · Male only" }, "enrollment_count": 0, "start_date": "2013-07", "completion_date": "2014-05", "has_results": false, "last_update_posted_date": "2016-11-01", "last_synced_at": "2026-09-30T21:04:00.380Z", "location_count": 1, "location_summary": "Knoxville, Tennessee", "locations": [ { "city": "Knoxville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT01902550" }, { "nct_id": "NCT01395329", "title": "Nebivolol and the Endothelin (ET)-1 System", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Prehypertension", "Hypertension" ], "interventions": [ { "name": "Nebivolol", "type": "DRUG" }, { "name": "Metoprolol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Forearm Blood Flow (FBF) response to BQ-123 (100 mol/min)", "type": "OTHER" }, { "name": "FBF response to BQ-123 (100 nmol/min)+BQ-788(50 nmol/min)", "type": "OTHER" }, { "name": "FBF response to Acetylcholine", "type": "OTHER" }, { "name": "FBF response to Sodium Nitroprusside", "type": "OTHER" }, { "name": "FBF response to BQ-123+BQ-788+ACh", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Colorado, Boulder", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "45 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "45 Years to 65 Years" }, "enrollment_count": 42, "start_date": "2011-05", "completion_date": "2016-12", "has_results": true, "last_update_posted_date": "2019-01-02", "last_synced_at": "2026-09-30T21:04:00.380Z", "location_count": 1, "location_summary": "Boulder, Colorado", "locations": [ { "city": "Boulder", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT01395329" }, { "nct_id": "NCT04254783", "title": "A Study to Evaluate the Effect of Intravenous (IV) Infusions of Risankizumab on Pharmacokinetics of Cytochome P450 Substrates in Adult Participants With Moderately to Severely Active Ulcerative Colitis or Crohn's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Ulcerative Colitis (UC)", "Crohn's Disease" ], "interventions": [ { "name": "Risankizumab", "type": "DRUG" }, { "name": "Cytochrome P450 (CYP) Substrates", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 20, "start_date": "2020-05-27", "completion_date": "2022-10-14", "has_results": false, "last_update_posted_date": "2024-07-01", "last_synced_at": "2026-09-30T21:04:00.380Z", "location_count": 4, "location_summary": "Coronado, California • DeLand, Florida • Margate, Florida + 1 more", "locations": [ { "city": "Coronado", "state": "California" }, { "city": "DeLand", "state": "Florida" }, { "city": "Margate", "state": "Florida" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04254783" }, { "nct_id": "NCT03696758", "title": "Improving Right Ventricular Function in Young Adults Born Preterm", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Infant,Premature" ], "interventions": [ { "name": "Pulmonary Function Testing", "type": "PROCEDURE" }, { "name": "Electrocardiogram", "type": "PROCEDURE" }, { "name": "Cardiac Magnetic Resonance Imaging", "type": "PROCEDURE" }, { "name": "Metoprolol", "type": "DRUG" }, { "name": "Sildenafil", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DRUG" ], "sponsor": "University of Wisconsin, Madison", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "35 Years", "sex": "ALL", "summary": "18 Years to 35 Years" }, "enrollment_count": 10, "start_date": "2018-10-30", "completion_date": "2020-02-24", "has_results": true, "last_update_posted_date": "2021-03-17", "last_synced_at": "2026-09-30T21:04:00.380Z", "location_count": 1, "location_summary": "Madison, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT03696758" }, { "nct_id": "NCT02940379", "title": "A Drug to Drug Interaction Study of Sotagliflozin With Midazolam and Metoprolol", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Type 2 Diabetes Mellitus" ], "interventions": [ { "name": "sotagliflozin (SAR439954)", "type": "DRUG" }, { "name": "midazolam", "type": "DRUG" }, { "name": "metoprolol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sanofi", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 24, "start_date": "2016-10", "completion_date": "2016-12", "has_results": false, "last_update_posted_date": "2022-04-25", "last_synced_at": "2026-09-30T21:04:00.380Z", "location_count": 1, "location_summary": "Knoxville, Tennessee", "locations": [ { "city": "Knoxville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT02940379" }, { "nct_id": "NCT03008382", "title": "Interstitial Cystitis: Examination of the Central Autonomic Network", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Interstitial Cystitis/Painful Bladder Syndrome", "Myofascial Pelvic Pain" ], "interventions": [ { "name": "Metoprolol Tartrate Oral Tablet", "type": "DRUG" }, { "name": "Placebo Oral Tablet", "type": "DRUG" }, { "name": "No intervention- observational sub-study", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Virginia Commonwealth University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "FEMALE", "summary": "18 Years to 80 Years · Female only" }, "enrollment_count": 72, "start_date": "2017-03-01", "completion_date": "2022-03-16", "has_results": true, "last_update_posted_date": "2025-02-17", "last_synced_at": "2026-09-30T21:04:00.380Z", "location_count": 2, "location_summary": "Evanston, Illinois • Richmond, Virginia", "locations": [ { "city": "Evanston", "state": "Illinois" }, { "city": "Richmond", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT03008382" }, { "nct_id": "NCT05891119", "title": "Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Atopic Dermatitis" ], "interventions": [ { "name": "Caffeine", "type": "DIETARY_SUPPLEMENT" }, { "name": "Metoprolol", "type": "DRUG" }, { "name": "Midazolam", "type": "DRUG" }, { "name": "Warfarin", "type": "DRUG" }, { "name": "Vitamin K", "type": "DIETARY_SUPPLEMENT" }, { "name": "Omeprazole", "type": "DRUG" }, { "name": "Rocatinlimab", "type": "DRUG" } ], "intervention_types": [ "DIETARY_SUPPLEMENT", "DRUG" ], "sponsor": "Amgen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 21, "start_date": "2023-06-03", "completion_date": "2025-02-12", "has_results": false, "last_update_posted_date": "2025-12-23", "last_synced_at": "2026-09-30T21:04:00.380Z", "location_count": 7, "location_summary": "North Hollywood, California • DeLand, Florida • Hialeah, Florida + 4 more", "locations": [ { "city": "North Hollywood", "state": "California" }, { "city": "DeLand", "state": "Florida" }, { "city": "Hialeah", "state": "Florida" }, { "city": "Dilworth", "state": "Minnesota" }, { "city": "Camp Hill", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT05891119" }, { "nct_id": "NCT04425902", "title": "Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "HIV Infections" ], "interventions": [ { "name": "GSK3640254 200 mg", "type": "DRUG" }, { "name": "Caffeine 200 mg", "type": "DRUG" }, { "name": "Metoprolol 100 mg", "type": "DRUG" }, { "name": "Montelukast 10 mg", "type": "DRUG" }, { "name": "Flurbiprofen 100 mg", "type": "DRUG" }, { "name": "Omeprazole 40 mg", "type": "DRUG" }, { "name": "Midazolam 5 mg (2.5 mL)", "type": "DRUG" }, { "name": "Digoxin 0.25 mg", "type": "DRUG" }, { "name": "Pravastatin 40 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "ViiV Healthcare", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 20, "start_date": "2020-12-16", "completion_date": "2021-03-10", "has_results": true, "last_update_posted_date": "2024-01-05", "last_synced_at": "2026-09-30T21:04:00.380Z", "location_count": 1, "location_summary": "Las Vegas, Nevada", "locations": [ { "city": "Las Vegas", "state": "Nevada" } ], "official_url": "https://clinicaltrials.gov/study/NCT04425902" }, { "nct_id": "NCT01595516", "title": "Nebivolol and Endothelial Regulation of Fibrinolysis (NERF)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Prehypertension", "Hypertension" ], "interventions": [ { "name": "Nebivolol", "type": "DRUG" }, { "name": "Metoprolol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Bradykinin", "type": "OTHER" }, { "name": "Saline", "type": "OTHER" }, { "name": "Vitamin C", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Colorado, Boulder", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "45 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "45 Years to 65 Years" }, "enrollment_count": 44, "start_date": "2012-02", "completion_date": "2017-10", "has_results": true, "last_update_posted_date": "2019-06-25", "last_synced_at": "2026-09-30T21:04:00.380Z", "location_count": 1, "location_summary": "Boulder, Colorado", "locations": [ { "city": "Boulder", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT01595516" }, { "nct_id": "NCT04713254", "title": "Drug Drug Interaction Study With Lu AG06466 in Young Healthy Men", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Lu AG06466", "type": "DRUG" }, { "name": "Midazolam", "type": "OTHER" }, { "name": "Metoprolol", "type": "OTHER" }, { "name": "Bupropion", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "H. Lundbeck A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 15, "start_date": "2020-12-08", "completion_date": "2021-04-09", "has_results": false, "last_update_posted_date": "2021-04-20", "last_synced_at": "2026-09-30T21:04:00.380Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04713254" } ] }