{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Microfracture&page=2",
    "query": {
      "intervention": "Microfracture",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Microfracture&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-07T14:18:54.552Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05082831",
      "title": "Human ECM Implanted Within Microfracture Interstices & the Cartilage Defect in the Knee to Regenerate Hyaline Cartilage",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Articular Cartilage Disorder of Knee",
        "Cartilage Damage",
        "Microfractures"
      ],
      "interventions": [
        {
          "name": "microfracture surgery + HST003",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Histogen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 1,
      "start_date": "2021-11-15",
      "completion_date": "2023-01-16",
      "has_results": false,
      "last_update_posted_date": "2023-01-19",
      "last_synced_at": "2026-09-07T14:18:54.552Z",
      "location_count": 5,
      "location_summary": "Vail, Colorado • Bradenton, Florida • Bethesda, Maryland + 2 more",
      "locations": [
        {
          "city": "Vail",
          "state": "Colorado"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "State College",
          "state": "Pennsylvania"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05082831"
    },
    {
      "nct_id": "NCT03299959",
      "title": "Agili-C™ Implant Performance Evaluation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cartilage or Osteochondral Defects in the Knee",
        "Up to Moderate Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Agili-C implant",
          "type": "DEVICE"
        },
        {
          "name": "SSOC",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Smith & Nephew, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 251,
      "start_date": "2017-09-25",
      "completion_date": "2024-11-14",
      "has_results": true,
      "last_update_posted_date": "2025-12-05",
      "last_synced_at": "2026-09-07T14:18:54.552Z",
      "location_count": 11,
      "location_summary": "San Diego, California • New Orleans, Louisiana • Salisbury, Maryland + 7 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Salisbury",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03299959"
    },
    {
      "nct_id": "NCT01957722",
      "title": "NOVOCART®3D for Treatment of Articular Cartilage of the Knee",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Articular Cartilage of the Femoral Condyle Between 2-6cm2"
      ],
      "interventions": [
        {
          "name": "Microfracture",
          "type": "PROCEDURE"
        },
        {
          "name": "NOVOCART 3D",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BIOLOGICAL"
      ],
      "sponsor": "Aesculap Biologics, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 233,
      "start_date": "2013-12",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2025-03-21",
      "last_synced_at": "2026-09-07T14:18:54.552Z",
      "location_count": 30,
      "location_summary": "La Mesa, California • Los Angeles, California • Redwood City, California + 26 more",
      "locations": [
        {
          "city": "La Mesa",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Redwood City",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Steamboat Springs",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01957722"
    },
    {
      "nct_id": "NCT04000659",
      "title": "Episealer® Knee System IDE Clinical Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Lesion of Articular Cartilage of Knee"
      ],
      "interventions": [
        {
          "name": "Episealer Knee System",
          "type": "DEVICE"
        },
        {
          "name": "Microfracture",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Episurf Medical Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "30 Years to 70 Years"
      },
      "enrollment_count": 13,
      "start_date": "2020-06-18",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2024-07-30",
      "last_synced_at": "2026-09-07T14:18:54.552Z",
      "location_count": 8,
      "location_summary": "Tempe, Arizona • La Mesa, California • New Orleans, Louisiana + 5 more",
      "locations": [
        {
          "city": "Tempe",
          "state": "Arizona"
        },
        {
          "city": "La Mesa",
          "state": "California"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Hackensack",
          "state": "New Jersey"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04000659"
    },
    {
      "nct_id": "NCT01621893",
      "title": "Evaluation of Subchondroplasty™ for Defects Associated With Bone Marrow Lesions",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bone Marrow Edema"
      ],
      "interventions": [
        {
          "name": "Subchondroplasty",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 70,
      "start_date": "2012-03-26",
      "completion_date": "2021-05-26",
      "has_results": false,
      "last_update_posted_date": "2021-09-24",
      "last_synced_at": "2026-09-07T14:18:54.552Z",
      "location_count": 6,
      "location_summary": "Encinitas, California • New Lenox, Illinois • New York, New York + 3 more",
      "locations": [
        {
          "city": "Encinitas",
          "state": "California"
        },
        {
          "city": "New Lenox",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01621893"
    },
    {
      "nct_id": "NCT01183637",
      "title": "Evaluation of an Acellular Osteochondral Graft for Cartilage LEsions Pilot Trial",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Articular Cartilage Injury"
      ],
      "interventions": [
        {
          "name": "Kensey Nash Corp. Cartilage Repair Device",
          "type": "DEVICE"
        },
        {
          "name": "Microfracture",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Kensey Nash Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2010-06",
      "completion_date": "2014-05",
      "has_results": false,
      "last_update_posted_date": "2015-05-25",
      "last_synced_at": "2026-09-07T14:18:54.552Z",
      "location_count": 2,
      "location_summary": "Salisbury, Maryland • Kirkwood, Missouri",
      "locations": [
        {
          "city": "Salisbury",
          "state": "Maryland"
        },
        {
          "city": "Kirkwood",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01183637"
    },
    {
      "nct_id": "NCT02090140",
      "title": "Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Lesion of Articular Cartilage of Knee"
      ],
      "interventions": [
        {
          "name": "ADSC Application",
          "type": "PROCEDURE"
        },
        {
          "name": "Microfracture",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 17,
      "start_date": "2015-11",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2024-04-25",
      "last_synced_at": "2026-09-07T14:18:54.552Z",
      "location_count": 3,
      "location_summary": "Redwood City, California • Santa Monica, California • Denver, Colorado",
      "locations": [
        {
          "city": "Redwood City",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02090140"
    },
    {
      "nct_id": "NCT00548119",
      "title": "NeoCart Phase 2 Clinical Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Articular Cartilage Damage"
      ],
      "interventions": [
        {
          "name": "NeoCart",
          "type": "BIOLOGICAL"
        },
        {
          "name": "microfracture",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "Histogenics Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 30,
      "start_date": "2006-12",
      "completion_date": "2014-03",
      "has_results": false,
      "last_update_posted_date": "2014-04-21",
      "last_synced_at": "2026-09-07T14:18:54.552Z",
      "location_count": 6,
      "location_summary": "San Francisco, California • Bloomington, Minnesota • New York, New York + 3 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Bloomington",
          "state": "Minnesota"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "West Point",
          "state": "New York"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00548119"
    },
    {
      "nct_id": "NCT01066702",
      "title": "Confirmatory Study of NeoCart in Knee Cartilage Repair",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Articular Cartilage Defects in the Knee Joint"
      ],
      "interventions": [
        {
          "name": "NeoCart",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Microfracture",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "Histogenics Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "59 Years",
        "sex": "ALL",
        "summary": "18 Years to 59 Years"
      },
      "enrollment_count": 245,
      "start_date": "2010-05",
      "completion_date": "2019-03",
      "has_results": false,
      "last_update_posted_date": "2019-03-29",
      "last_synced_at": "2026-09-07T14:18:54.552Z",
      "location_count": 29,
      "location_summary": "Tucson, Arizona • La Mesa, California • Orange, California + 26 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "La Mesa",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Van Nuys",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01066702"
    },
    {
      "nct_id": "NCT02308358",
      "title": "Long Term Outcomes of Osteochondral Allografts for Osteochondral Defects of the Knee",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Outcomes of Allograft"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2014-05",
      "completion_date": "2015-07",
      "has_results": false,
      "last_update_posted_date": "2023-08-30",
      "last_synced_at": "2026-09-07T14:18:54.552Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02308358"
    }
  ]
}