{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Milk+fortification",
    "query": {
      "intervention": "Milk fortification"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 23,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Milk+fortification&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T09:44:13.057Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02860702",
      "title": "Exclusive Human Milk Feeding in Infants With Single Ventricle Physiology",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Congenital Heart Defect"
      ],
      "interventions": [
        {
          "name": "Human Milk Derived Fortifier",
          "type": "OTHER"
        },
        {
          "name": "Human/Bovine Milk",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "7 Days",
        "sex": "ALL",
        "summary": "1 Day to 7 Days"
      },
      "enrollment_count": 16,
      "start_date": "2016-07",
      "completion_date": "2022-10-06",
      "has_results": false,
      "last_update_posted_date": "2023-09-26",
      "last_synced_at": "2026-09-04T09:44:13.057Z",
      "location_count": 12,
      "location_summary": "Loma Linda, California • Los Angeles, California • Orange, California + 9 more",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02860702"
    },
    {
      "nct_id": "NCT04284280",
      "title": "Early Routine vs. Selective Human Milk Fortification in Extremely Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Poor Growth in Extremely Preterm Infants",
        "Necrotizing Enterocolitis"
      ],
      "interventions": [
        {
          "name": "Routine vs Selective use of Human Milk Donor Fortifier",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Crouse Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "6 Days",
        "sex": "ALL",
        "summary": "0 Days to 6 Days"
      },
      "enrollment_count": 170,
      "start_date": "2020-02-15",
      "completion_date": "2025-11-11",
      "has_results": false,
      "last_update_posted_date": "2026-04-30",
      "last_synced_at": "2026-09-04T09:44:13.057Z",
      "location_count": 1,
      "location_summary": "Syracuse, New York",
      "locations": [
        {
          "city": "Syracuse",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04284280"
    },
    {
      "nct_id": "NCT00760942",
      "title": "Liquid Preterm Formula Versus Powdered Human Milk Fortifier in VLBW Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant, Very Low Birth Weight"
      ],
      "interventions": [
        {
          "name": "Similac special care 30",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Similac human milk fortifier",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "10 Weeks",
        "sex": "ALL",
        "summary": "1 Day to 10 Weeks"
      },
      "enrollment_count": 84,
      "start_date": "2008-10",
      "completion_date": "2010-09",
      "has_results": false,
      "last_update_posted_date": "2013-12-10",
      "last_synced_at": "2026-09-04T09:44:13.057Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00760942"
    },
    {
      "nct_id": "NCT01747668",
      "title": "Lactation Fortification Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Lactation"
      ],
      "interventions": [
        {
          "name": "Similac Prenatal Vitamin soft-gel capsule",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo (soybean oil and dl-alpha-tocopheryl acetate)",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Abbott Nutrition",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 89,
      "start_date": "2012-11",
      "completion_date": "2013-04",
      "has_results": false,
      "last_update_posted_date": "2013-05-31",
      "last_synced_at": "2026-09-04T09:44:13.057Z",
      "location_count": 6,
      "location_summary": "Indianapolis, Indiana • Dayton, Ohio • Kettering, Ohio + 3 more",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Dayton",
          "state": "Ohio"
        },
        {
          "city": "Kettering",
          "state": "Ohio"
        },
        {
          "city": "Mayfield Heights",
          "state": "Ohio"
        },
        {
          "city": "Parma",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01747668"
    },
    {
      "nct_id": "NCT05228535",
      "title": "Human Milk in Preterm Infants",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Preterm Birth"
      ],
      "interventions": [
        {
          "name": "Human milk fortifier",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Augusta University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "4 Days",
        "sex": "ALL",
        "summary": "Up to 4 Days"
      },
      "enrollment_count": 50,
      "start_date": "2022-04-11",
      "completion_date": "2023-12",
      "has_results": false,
      "last_update_posted_date": "2022-07-21",
      "last_synced_at": "2026-09-04T09:44:13.057Z",
      "location_count": 1,
      "location_summary": "Augusta, Georgia",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05228535"
    },
    {
      "nct_id": "NCT05515614",
      "title": "Targeted Nutrition for Moderate to Late Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature Birth",
        "Breastmilk Collection",
        "Postnatal Growth Restriction"
      ],
      "interventions": [
        {
          "name": "Targeted Fortification",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Enfamil Liquid Human Milk Fortifier",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 34,
      "start_date": "2022-08-17",
      "completion_date": "2023-05-11",
      "has_results": false,
      "last_update_posted_date": "2025-02-24",
      "last_synced_at": "2026-09-04T09:44:13.057Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05515614"
    },
    {
      "nct_id": "NCT05525585",
      "title": "Early Human Milk Fortification After Early, Exclusive, Enteral Nutrition in Very Preterm Infants",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prematurity",
        "Light-For-Dates",
        "Enteral Feeding Intolerance"
      ],
      "interventions": [
        {
          "name": "Early HMF",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Delayed HMF",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "4 Days",
        "sex": "ALL",
        "summary": "1 Day to 4 Days"
      },
      "enrollment_count": 80,
      "start_date": "2022-11-17",
      "completion_date": "2027-05",
      "has_results": false,
      "last_update_posted_date": "2026-06-15",
      "last_synced_at": "2026-09-04T09:44:13.057Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05525585"
    },
    {
      "nct_id": "NCT07562997",
      "title": "Sodium and Milk Fortification Evaluation of Body Composition Among Very Preterm Infants",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Very Preterm and Extremely Preterm Birth"
      ],
      "interventions": [
        {
          "name": "Urine sodium testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum sodium testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Milk fortification",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "14 Days",
        "sex": "ALL",
        "summary": "0 Days to 14 Days"
      },
      "enrollment_count": 150,
      "start_date": "2026-05-18",
      "completion_date": "2029-10-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-28",
      "last_synced_at": "2026-09-04T09:44:13.057Z",
      "location_count": 3,
      "location_summary": "Cincinnati, Ohio • Portland, Oregon • Seattle, Washington",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07562997"
    },
    {
      "nct_id": "NCT03586102",
      "title": "Effect of Increased Enteral Protein on Body Composition of Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Premature Infant"
      ],
      "interventions": [
        {
          "name": "High protein supplementation",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Standard protein supplementation",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "21 Days",
        "sex": "ALL",
        "summary": "1 Day to 21 Days"
      },
      "enrollment_count": 56,
      "start_date": "2018-08-23",
      "completion_date": "2025-04-24",
      "has_results": false,
      "last_update_posted_date": "2025-05-28",
      "last_synced_at": "2026-09-04T09:44:13.057Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03586102"
    },
    {
      "nct_id": "NCT00486590",
      "title": "Evaluation of Prolact-Plus Human Milk Fortifier",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infant, Very Low Birth Weight"
      ],
      "interventions": [
        {
          "name": "Prolact-Plus Human Milk Fortifier",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Prolacta Bioscience",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "30 Days",
        "sex": "ALL",
        "summary": "1 Day to 30 Days"
      },
      "enrollment_count": 105,
      "start_date": "2006-08",
      "completion_date": "2007-08",
      "has_results": false,
      "last_update_posted_date": "2021-09-17",
      "last_synced_at": "2026-09-04T09:44:13.057Z",
      "location_count": 4,
      "location_summary": "Gainesville, Florida • Hollywood, Florida • Miami, Florida + 1 more",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "South Bend",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00486590"
    }
  ]
}