{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Mineral+Trioxide+Aggregate",
    "query": {
      "intervention": "Mineral Trioxide Aggregate"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Mineral+Trioxide+Aggregate&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T03:52:33.484Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03425123",
      "title": "Endodontic Regenerative Procedure for Immature Non-vital Teeth",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tooth, Nonvital"
      ],
      "interventions": [
        {
          "name": "Regenerative Endodontic Procedure (REP)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "7 Years to 18 Years"
      },
      "enrollment_count": 0,
      "start_date": "2019-06",
      "completion_date": "2023-01",
      "has_results": false,
      "last_update_posted_date": "2019-05-03",
      "last_synced_at": "2026-09-06T03:52:33.484Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03425123"
    },
    {
      "nct_id": "NCT02620826",
      "title": "Prospective Comparison of Indirect Pulp Therapy and Mineral Trioxide Aggregate Pulpotomy in Decayed Primary Molars",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Pulp Capping"
      ],
      "interventions": [
        {
          "name": "Indirect pulp therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Pulpotomy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "2 Years to 12 Years"
      },
      "enrollment_count": 110,
      "start_date": "2013-12",
      "completion_date": "2019-12",
      "has_results": false,
      "last_update_posted_date": "2024-02-06",
      "last_synced_at": "2026-09-06T03:52:33.484Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02620826"
    },
    {
      "nct_id": "NCT02635867",
      "title": "Clinical Comparison of Vital Pulp Capping Restorative Protocols",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Deep Dental Caries"
      ],
      "interventions": [
        {
          "name": "Indirect Pulp capping-Resin-modified calcium silicate - TheraCal",
          "type": "PROCEDURE"
        },
        {
          "name": "Indirect Pulp capping-Calcium hydroxide - Dycal",
          "type": "PROCEDURE"
        },
        {
          "name": "Indirect Pulp capping-Resin-based dentin bonding agent",
          "type": "PROCEDURE"
        },
        {
          "name": "Direct Pulp capping-Resin-modified calcium silicate - TheraCal",
          "type": "PROCEDURE"
        },
        {
          "name": "Direct Pulp capping-Calcium hydroxide - Dycal",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 109,
      "start_date": "2015-06",
      "completion_date": "2019-08",
      "has_results": true,
      "last_update_posted_date": "2023-10-12",
      "last_synced_at": "2026-09-06T03:52:33.484Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02635867"
    },
    {
      "nct_id": "NCT03613090",
      "title": "Novel Collagen Scaffold vs Conventional Scaffold in Regeneration of Human Dental Pulp Tissue",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Root Canal Therapy"
      ],
      "interventions": [
        {
          "name": "Collagen-hydroxyapatite scaffold (Syn-Oss)",
          "type": "DRUG"
        },
        {
          "name": "Collagen Scaffold (Colla-Plug)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2019-04-01",
      "completion_date": "2019-04-01",
      "has_results": false,
      "last_update_posted_date": "2019-05-23",
      "last_synced_at": "2026-09-06T03:52:33.484Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03613090"
    },
    {
      "nct_id": "NCT00595842",
      "title": "Artificial Root-End Barriers",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dental Cements",
        "Tooth Abnormalities"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "5 Years to 40 Years"
      },
      "enrollment_count": 10,
      "start_date": "2007-02",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2012-03-08",
      "last_synced_at": "2026-09-06T03:52:33.484Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00595842"
    },
    {
      "nct_id": "NCT00812877",
      "title": "Pulp Capping With Two Different Agents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Pulp Exposure"
      ],
      "interventions": [
        {
          "name": "Mineral Trioxide Aggregate",
          "type": "DRUG"
        },
        {
          "name": "Calcium Hydroxide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "7 Years and older"
      },
      "enrollment_count": 376,
      "start_date": "2009-05",
      "completion_date": "2012-05",
      "has_results": true,
      "last_update_posted_date": "2015-05-25",
      "last_synced_at": "2026-09-06T03:52:33.484Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00812877"
    },
    {
      "nct_id": "NCT02702505",
      "title": "Success and Color Stability of MTA Pulpotomized Primary Molars: an RCT",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Reversible Pulpitis",
        "Dental Pulp Diseases"
      ],
      "interventions": [
        {
          "name": "NeoMTA",
          "type": "BIOLOGICAL"
        },
        {
          "name": "ProRoot MTA",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Texas A & M University Baylor College Of Dentistry",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "8 Years",
        "sex": "ALL",
        "summary": "2 Years to 8 Years"
      },
      "enrollment_count": 50,
      "start_date": "2014-11",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2016-03-08",
      "last_synced_at": "2026-09-06T03:52:33.484Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02702505"
    },
    {
      "nct_id": "NCT04863222",
      "title": "Clinical and Radiographic Success of MTA vs Biodentine",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Indirect Pulp Cap",
        "Pulpotomy"
      ],
      "interventions": [
        {
          "name": "Biodentine",
          "type": "DEVICE"
        },
        {
          "name": "mineral trioxide aggregate (MTA)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BIOLOGICAL"
      ],
      "sponsor": "Geisinger Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "2 Years to 12 Years"
      },
      "enrollment_count": 646,
      "start_date": "2021-11-12",
      "completion_date": "2026-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-12-23",
      "last_synced_at": "2026-09-06T03:52:33.484Z",
      "location_count": 1,
      "location_summary": "Danville, Pennsylvania",
      "locations": [
        {
          "city": "Danville",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04863222"
    },
    {
      "nct_id": "NCT00881491",
      "title": "Treatment Outcome With a Revascularization Protocol Using the Triple Versus Double Antibiotic Paste",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Pulp Necrosis"
      ],
      "interventions": [
        {
          "name": "Double Antibiotic Paste",
          "type": "DRUG"
        },
        {
          "name": "Triple Antibiotic Paste",
          "type": "DRUG"
        },
        {
          "name": "Mineral Trioxide Aggregate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "7 Years to 60 Years"
      },
      "enrollment_count": 10,
      "start_date": "2009-04",
      "completion_date": "2015-01",
      "has_results": false,
      "last_update_posted_date": "2016-02-05",
      "last_synced_at": "2026-09-06T03:52:33.484Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00881491"
    },
    {
      "nct_id": "NCT02298504",
      "title": "Vital Pulp Treatment in Primary Teeth",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Vital Pulp Therapies",
        "Indirect Pulp Cap",
        "Pulpotomy"
      ],
      "interventions": [
        {
          "name": "Mineral Trioxide Aggregate",
          "type": "DRUG"
        },
        {
          "name": "Biodentin",
          "type": "DRUG"
        },
        {
          "name": "Vitrebond",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "9 Years",
        "sex": "ALL",
        "summary": "2 Years to 9 Years"
      },
      "enrollment_count": 76,
      "start_date": "2018-07-01",
      "completion_date": "2026-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-23",
      "last_synced_at": "2026-09-06T03:52:33.484Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02298504"
    }
  ]
}