{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Minocycline+Topical&page=2", "query": { "intervention": "Minocycline Topical", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 26, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Minocycline+Topical&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Minocycline+Topical&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-02T15:27:51.380Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03276936", "title": "A Study to Evaluate the Long-Term Safety of Topical Administration of FMX103 in the Treatment of Moderate to Severe Papulopustular Rosacea", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Papulopustular Rosacea" ], "interventions": [ { "name": "FMX103 1.5%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vyne Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 504, "start_date": "2017-09-05", "completion_date": "2019-01-15", "has_results": true, "last_update_posted_date": "2022-01-18", "last_synced_at": "2026-10-02T15:27:51.380Z", "location_count": 79, "location_summary": "Glendale, Arizona • Hot Springs, Arkansas • Rogers, Arkansas + 72 more", "locations": [ { "city": "Glendale", "state": "Arizona" }, { "city": "Hot Springs", "state": "Arkansas" }, { "city": "Rogers", "state": "Arkansas" }, { "city": "Fremont", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03276936" }, { "nct_id": "NCT04940767", "title": "A Companion Treatment Study for Patients With Moderate to Severe Acne Vulgaris", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Acne Vulgaris" ], "interventions": [ { "name": "Isotretinoin", "type": "DRUG" }, { "name": "Amzeeq 4% Topical Foam", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Edward Lain, MD", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 31, "start_date": "2021-06-28", "completion_date": "2023-04-28", "has_results": false, "last_update_posted_date": "2023-06-22", "last_synced_at": "2026-10-02T15:27:51.380Z", "location_count": 2, "location_summary": "Dripping Springs, Texas • Pflugerville, Texas", "locations": [ { "city": "Dripping Springs", "state": "Texas" }, { "city": "Pflugerville", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04940767" }, { "nct_id": "NCT04104685", "title": "A Study to Compare FCD105 Foam to Minocycline 3% Foam, Adapalene 0.3% Foam and Vehicle Foam.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Acne Vulgaris" ], "interventions": [ { "name": "FCD105", "type": "COMBINATION_PRODUCT" }, { "name": "3% Minocycline Foam", "type": "DRUG" }, { "name": "0.3% Adapalene Foam", "type": "DRUG" }, { "name": "Vehicle Foam", "type": "OTHER" } ], "intervention_types": [ "COMBINATION_PRODUCT", "DRUG", "OTHER" ], "sponsor": "Vyne Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 446, "start_date": "2019-09-18", "completion_date": "2020-03-03", "has_results": false, "last_update_posted_date": "2021-02-05", "last_synced_at": "2026-10-02T15:27:51.380Z", "location_count": 35, "location_summary": "Bryant, Arkansas • Rogers, Arkansas • Encino, California + 32 more", "locations": [ { "city": "Bryant", "state": "Arkansas" }, { "city": "Rogers", "state": "Arkansas" }, { "city": "Encino", "state": "California" }, { "city": "Fremont", "state": "California" }, { "city": "Huntington Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04104685" }, { "nct_id": "NCT03142451", "title": "A Study (Study 1) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Facial Papulopustular Rosacea" ], "interventions": [ { "name": "FMX103 minocycline foam 1.5%", "type": "DRUG" }, { "name": "Vehicle foam", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vyne Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 751, "start_date": "2017-06-02", "completion_date": "2018-09-28", "has_results": true, "last_update_posted_date": "2021-01-29", "last_synced_at": "2026-10-02T15:27:51.380Z", "location_count": 54, "location_summary": "Tucson, Arizona • Fremont, California • Los Angeles, California + 46 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Fremont", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Northridge", "state": "California" }, { "city": "Oceanside", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03142451" }, { "nct_id": "NCT07298057", "title": "Effect of Arestin-Enhanced SRP on Periodontal and Glycemic Outcomes in Diabetics", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Periodontitis, Diabetes Mellitus Type 2" ], "interventions": [ { "name": "local antibiotic application of topical minocycline", "type": "DRUG" }, { "name": "Scaling and Root Planing", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Case Western Reserve University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 42, "start_date": "2026-02-06", "completion_date": "2028-06", "has_results": false, "last_update_posted_date": "2026-02-19", "last_synced_at": "2026-10-02T15:27:51.380Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT07298057" }, { "nct_id": "NCT02815280", "title": "A Study to Compare the Efficacy and Safety of Topical Administration of FMX-101 for Treatment of Moderate-to-Severe Acne", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Acne Vulgaris" ], "interventions": [ { "name": "FMX-101, 4% minocycline foam", "type": "DRUG" }, { "name": "Vehicle Foam", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vyne Therapeutics Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "9 Years", "maximum_age": null, "sex": "ALL", "summary": "9 Years and older" }, "enrollment_count": 495, "start_date": "2016-05", "completion_date": "2017-10-13", "has_results": true, "last_update_posted_date": "2022-01-18", "last_synced_at": "2026-10-02T15:27:51.380Z", "location_count": 35, "location_summary": "Glendale, Arizona • Rogers, Arkansas • Oceanside, California + 31 more", "locations": [ { "city": "Glendale", "state": "Arizona" }, { "city": "Rogers", "state": "Arkansas" }, { "city": "Oceanside", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Hialeah", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02815280" }, { "nct_id": "NCT03263273", "title": "Study to Evaluate the Safety and Efficacy of Topical Minocycline Gel in Patients With Papulopustular Rosacea", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Rosacea", "Papulopustular Rosacea" ], "interventions": [ { "name": "1% Topical Minocycline Gel", "type": "DRUG" }, { "name": "3% Topical Minocycline Gel", "type": "DRUG" }, { "name": "Topical Vehicle Gel", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Hovione Scientia Limited", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 270, "start_date": "2017-10-30", "completion_date": "2019-07-01", "has_results": false, "last_update_posted_date": "2019-11-08", "last_synced_at": "2026-10-02T15:27:51.380Z", "location_count": 23, "location_summary": "Bryant, Arkansas • Rogers, Arkansas • Fremont, California + 17 more", "locations": [ { "city": "Bryant", "state": "Arkansas" }, { "city": "Rogers", "state": "Arkansas" }, { "city": "Fremont", "state": "California" }, { "city": "Santa Monica", "state": "California" }, { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03263273" }, { "nct_id": "NCT04721626", "title": "Topical Antisepsis in Head and Neck Cancer Surgery", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Head and Neck Cancer" ], "interventions": [ { "name": "Chlorhexidine Gluconate", "type": "DRUG" }, { "name": "Povidone-iodine", "type": "DRUG" }, { "name": "Tetracycline Ointment", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Medical College of Wisconsin", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 25, "start_date": "2021-01-06", "completion_date": "2021-10-04", "has_results": false, "last_update_posted_date": "2022-02-07", "last_synced_at": "2026-10-02T15:27:51.380Z", "location_count": 1, "location_summary": "Milwaukee, Wisconsin", "locations": [ { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT04721626" }, { "nct_id": "NCT03667222", "title": "Topical Minocycline Gel for Inflammatory Lesions of Papulopustular Rosacea", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Papulopustular Rosacea" ], "interventions": [ { "name": "minocycline topical gel", "type": "DRUG" }, { "name": "topical gel vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "BioPharmX, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 207, "start_date": "2018-09-18", "completion_date": "2019-08-17", "has_results": false, "last_update_posted_date": "2019-07-10", "last_synced_at": "2026-10-02T15:27:51.380Z", "location_count": 12, "location_summary": "Anaheim Hills, California • Miami, Florida • Miramar, Florida + 9 more", "locations": [ { "city": "Anaheim Hills", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Miramar", "state": "Florida" }, { "city": "Baton Rouge", "state": "Louisiana" }, { "city": "New Orleans", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT03667222" }, { "nct_id": "NCT03050086", "title": "Open Label Phase 2 Feasibility Study of BPX-04 Topical Minocycline Gel in Rosacea", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Moderate to Severe Papulopustular Rosacea" ], "interventions": [ { "name": "BPX-04 1% minocycline topical gel", "type": "DRUG" }, { "name": "BPX-04 2% minocycline topical gel", "type": "DRUG" }, { "name": "BPX-04 vehicle topical gel", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "BioPharmX, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2017-03-29", "completion_date": "2018-06-19", "has_results": false, "last_update_posted_date": "2019-01-31", "last_synced_at": "2026-10-02T15:27:51.380Z", "location_count": 1, "location_summary": "San Diego, California", "locations": [ { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03050086" } ] }