{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Mitral+valve+repair&page=3",
    "query": {
      "intervention": "Mitral valve repair",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 70,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Mitral+valve+repair&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Mitral+valve+repair&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-06T00:36:13.366Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00903370",
      "title": "Surgical Ablation Versus No Surgical Ablation for Patients With Atrial Fibrillation Undergoing Mitral Valve Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Atrial Fibrillation",
        "Mitral Valve Insufficiency",
        "Mitral Valve Stenosis"
      ],
      "interventions": [
        {
          "name": "MVS",
          "type": "PROCEDURE"
        },
        {
          "name": "Ablation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Annetine Gelijns",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 260,
      "start_date": "2010-01",
      "completion_date": "2015-09",
      "has_results": true,
      "last_update_posted_date": "2017-02-06",
      "last_synced_at": "2026-10-06T00:36:13.366Z",
      "location_count": 18,
      "location_summary": "New Haven, Connecticut • Newark, Delaware • Atlanta, Georgia + 14 more",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Newark",
          "state": "Delaware"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00903370"
    },
    {
      "nct_id": "NCT02803957",
      "title": "Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mitral Valve Insufficiency"
      ],
      "interventions": [
        {
          "name": "NeoChord DS1000",
          "type": "DEVICE"
        },
        {
          "name": "Surgical Mitral Valve Repair",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "NeoChord",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 585,
      "start_date": "2016-11-03",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-08",
      "last_synced_at": "2026-10-06T00:36:13.366Z",
      "location_count": 14,
      "location_summary": "Sacramento, California • Stanford, California • Washington D.C., District of Columbia + 10 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02803957"
    },
    {
      "nct_id": "NCT00807040",
      "title": "Comparing the Effectiveness of Repairing Versus Replacing the Heart's Mitral Valve in People With Severe Chronic Ischemic Mitral Regurgitation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Mitral Valve Insufficiency",
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "Mitral Valve Repair with Annuloplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "Mitral Valve Replacement",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 251,
      "start_date": "2008-12",
      "completion_date": "2014-03",
      "has_results": true,
      "last_update_posted_date": "2019-03-15",
      "last_synced_at": "2026-10-06T00:36:13.366Z",
      "location_count": 18,
      "location_summary": "Los Angeles, California • Atlanta, Georgia • Marietta, Georgia + 15 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Marietta",
          "state": "Georgia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00807040"
    },
    {
      "nct_id": "NCT01931956",
      "title": "Real World Expanded Multicenter Study of the MitraClip® System (REALISM)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mitral Valve Insufficiency",
        "Mitral Valve Regurgitation",
        "Mitral Valve Incompetence",
        "Mitral Regurgitation",
        "Mitral Insufficiency"
      ],
      "interventions": [
        {
          "name": "MitraClip® implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 965,
      "start_date": "2009-01-22",
      "completion_date": "2018-06",
      "has_results": true,
      "last_update_posted_date": "2018-12-04",
      "last_synced_at": "2026-10-06T00:36:13.366Z",
      "location_count": 38,
      "location_summary": "Los Angeles, California • Mountain View, California • Sacramento, California + 31 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Mountain View",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01931956"
    },
    {
      "nct_id": "NCT03079401",
      "title": "Mesoblast Stem Cell Therapy for Patients With Single Ventricle and Borderline Left Ventricle",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Hypoplastic Left Heart Syndrome",
        "Atrioventricular Canal"
      ],
      "interventions": [
        {
          "name": "MPC; rexlemestrocel-L",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "5 Years",
        "sex": "ALL",
        "summary": "Up to 5 Years"
      },
      "enrollment_count": 19,
      "start_date": "2017-11-27",
      "completion_date": "2024-01",
      "has_results": false,
      "last_update_posted_date": "2023-04-21",
      "last_synced_at": "2026-10-06T00:36:13.366Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03079401"
    },
    {
      "nct_id": "NCT03142152",
      "title": "The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Functional Mitral Regurgitation",
        "Heart Failure",
        "Mitral Valve Insufficiency",
        "Heart Diseases",
        "Cardiovascular Diseases",
        "Heart Valve Diseases"
      ],
      "interventions": [
        {
          "name": "Carillon Mitral Contour System",
          "type": "DEVICE"
        },
        {
          "name": "Guideline Directed Heart Failure Medication",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Cardiac Dimensions, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2018-01-01",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-10-06T00:36:13.366Z",
      "location_count": 75,
      "location_summary": "Gilbert, Arizona • Phoenix, Arizona • Tucson, Arizona + 61 more",
      "locations": [
        {
          "city": "Gilbert",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03142152"
    },
    {
      "nct_id": "NCT03012178",
      "title": "MRI as a Predictor of Outcomes in Patients Undergoing Mitral Valve Surgery",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mitral Valve Insufficiency"
      ],
      "interventions": [
        {
          "name": "Mitral valve surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Atlantic Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2017-01",
      "completion_date": "2020-12",
      "has_results": false,
      "last_update_posted_date": "2018-01-11",
      "last_synced_at": "2026-10-06T00:36:13.366Z",
      "location_count": 1,
      "location_summary": "Morristown, New Jersey",
      "locations": [
        {
          "city": "Morristown",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03012178"
    },
    {
      "nct_id": "NCT07103733",
      "title": "PRIMARY Ancillary Substudy",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mitral Valve Prolapse",
        "Left Ventricular Fibrosis",
        "Ventricular Arrhythmias"
      ],
      "interventions": [
        {
          "name": "Cardiac Magnetic Resonance Imaging",
          "type": "PROCEDURE"
        },
        {
          "name": "ZioPatch Monitoring",
          "type": "DEVICE"
        },
        {
          "name": "Myocardial Tissue Biopsy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Annetine Gelijns",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 250,
      "start_date": "2023-10-16",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-08",
      "last_synced_at": "2026-10-06T00:36:13.366Z",
      "location_count": 16,
      "location_summary": "Los Angeles, California • San Francisco, California • Stanford, California + 11 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07103733"
    },
    {
      "nct_id": "NCT06911099",
      "title": "Assessment of Transcatheter Edge-to-Edge Repair in Atrial Functional Mitral Regurgitation (ATRIAL-MR)",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Atrial Functional Mitral Regurgitation",
        "Mitral Insufficiency"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University Hospital of Cologne",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2010-01-01",
      "completion_date": "2035-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-04-06",
      "last_synced_at": "2026-10-06T00:36:13.366Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06911099"
    },
    {
      "nct_id": "NCT03016975",
      "title": "Edwards Cardioband System ACTIVE Pivotal Clinical Trial (ACTIVE)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Functional Mitral Regurgitation",
        "Mitral Regurgitation",
        "Mitral Insufficiency"
      ],
      "interventions": [
        {
          "name": "Edwards Cardioband System",
          "type": "DEVICE"
        },
        {
          "name": "Guideline Directed Medical Therapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Edwards Lifesciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2017-06-01",
      "completion_date": "2022-09-20",
      "has_results": true,
      "last_update_posted_date": "2023-11-30",
      "last_synced_at": "2026-10-06T00:36:13.366Z",
      "location_count": 24,
      "location_summary": "Los Angeles, California • Palo Alto, California • Aurora, Colorado + 18 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03016975"
    }
  ]
}