{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Modified+amputation+procedure&page=2",
    "query": {
      "intervention": "Modified amputation procedure",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Modified+amputation+procedure&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-11T22:32:24.446Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03374319",
      "title": "Somatotopic Configuration of Distal Residual Limb Tissues in Lower Extremity Amputations",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Modified amputation procedure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 50,
      "start_date": "2017-09-15",
      "completion_date": "2024-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-09-11T22:32:24.446Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03374319"
    },
    {
      "nct_id": "NCT02440295",
      "title": "Pilot Study to Assess the Use of Spy Elite for Assessment of Amputation Healing",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Wound Healing",
        "Lower Extremity Amputation",
        "Above Knee Amputation",
        "Below Knee Amputation"
      ],
      "interventions": [
        {
          "name": "Lower Extremity Amputation",
          "type": "PROCEDURE"
        },
        {
          "name": "SPY Elite Imaging System",
          "type": "DEVICE"
        },
        {
          "name": "Indocyaine Green",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Corewell Health West",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2015-05",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2023-09-28",
      "last_synced_at": "2026-09-11T22:32:24.446Z",
      "location_count": 1,
      "location_summary": "Grand Rapids, Michigan",
      "locations": [
        {
          "city": "Grand Rapids",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02440295"
    },
    {
      "nct_id": "NCT06371209",
      "title": "Kinematics of Ewing Amputees",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lower Extremity Amputation",
        "Trans-Tibial Amputation",
        "Traumatic Lower Extremity Amputation",
        "Agonist-Antagonist Myoneural Interface"
      ],
      "interventions": [
        {
          "name": "Modified Amputation",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard Amputation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 32,
      "start_date": "2022-05-17",
      "completion_date": "2026-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-09-11T22:32:24.446Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06371209"
    },
    {
      "nct_id": "NCT00932399",
      "title": "Longitudinal Study of Weight Change Following Lower Limb Amputation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Amputation Wound",
        "Traumatic Amputation of Toe",
        "Dysvascular Amputation of Lower Limb"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "27 Years",
        "maximum_age": "89 Years",
        "sex": "MALE",
        "summary": "27 Years to 89 Years · Male only"
      },
      "enrollment_count": 4549,
      "start_date": "2010-03",
      "completion_date": "2016-01",
      "has_results": true,
      "last_update_posted_date": "2016-02-08",
      "last_synced_at": "2026-09-11T22:32:24.446Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00932399"
    },
    {
      "nct_id": "NCT04494555",
      "title": "Do Adaptable Sockets Improve Military Performance?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation Stump"
      ],
      "interventions": [
        {
          "name": "Static socket",
          "type": "DEVICE"
        },
        {
          "name": "User adjusted socket",
          "type": "DEVICE"
        },
        {
          "name": "Microprocessor-adjusting sockets",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Brooke Army Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 15,
      "start_date": "2020-11-04",
      "completion_date": "2024-01-10",
      "has_results": false,
      "last_update_posted_date": "2025-02-05",
      "last_synced_at": "2026-09-11T22:32:24.446Z",
      "location_count": 1,
      "location_summary": "Fort Sam Houston, Texas",
      "locations": [
        {
          "city": "Fort Sam Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04494555"
    },
    {
      "nct_id": "NCT04924036",
      "title": "Qbrexza Cloths for Hyperhidrosis of Amputation Sites",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Amputation",
        "Hyperhidrosis"
      ],
      "interventions": [
        {
          "name": "glycopyrronium cloths",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2021-09-27",
      "completion_date": "2023-12-03",
      "has_results": true,
      "last_update_posted_date": "2026-01-22",
      "last_synced_at": "2026-09-11T22:32:24.446Z",
      "location_count": 1,
      "location_summary": "Murray, Utah",
      "locations": [
        {
          "city": "Murray",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04924036"
    },
    {
      "nct_id": "NCT01645722",
      "title": "Enriched Autologous Fat Grafting for Treating Pain at Amputation Sites",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation Stumps",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Procedure/Surgery: Enriched Fat grafting",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2012-07",
      "completion_date": "2016-09-14",
      "has_results": false,
      "last_update_posted_date": "2017-10-25",
      "last_synced_at": "2026-09-11T22:32:24.446Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01645722"
    },
    {
      "nct_id": "NCT04405050",
      "title": "RCT to Compare Restrata and NPWT to Heal Complex DFUs",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetic Wound"
      ],
      "interventions": [
        {
          "name": "Restrata",
          "type": "DEVICE"
        },
        {
          "name": "Negative Pressure Wound Therapy (NPWT)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2021-06",
      "completion_date": "2023-07",
      "has_results": false,
      "last_update_posted_date": "2023-07-24",
      "last_synced_at": "2026-09-11T22:32:24.446Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04405050"
    },
    {
      "nct_id": "NCT02163811",
      "title": "Self-management to Improve Function Following Amputation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation, Limb Loss"
      ],
      "interventions": [
        {
          "name": "VETPALS",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Individual Education Support Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 182,
      "start_date": "2014-07-01",
      "completion_date": "2019-03-21",
      "has_results": true,
      "last_update_posted_date": "2020-08-05",
      "last_synced_at": "2026-09-11T22:32:24.446Z",
      "location_count": 5,
      "location_summary": "Tampa, Florida • Minneapolis, Minnesota • Cleveland, Ohio + 2 more",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02163811"
    },
    {
      "nct_id": "NCT02813161",
      "title": "The Diabetic Foot Ulcer Registry",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetic Foot Ulcer Outcome",
        "Quality of Patient Care"
      ],
      "interventions": [
        {
          "name": "cellular and tissue based therapy",
          "type": "BIOLOGICAL"
        },
        {
          "name": "negative pressure wound therapy",
          "type": "DEVICE"
        },
        {
          "name": "debridement",
          "type": "PROCEDURE"
        },
        {
          "name": "advanced wound therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Nutritional screening",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "off-loading",
          "type": "DEVICE"
        },
        {
          "name": "Hyperbaric oxygen Therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DEVICE",
        "PROCEDURE",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "U.S. Wound Registry",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 10000,
      "start_date": "2015-02",
      "completion_date": "2025-02",
      "has_results": false,
      "last_update_posted_date": "2018-05-03",
      "last_synced_at": "2026-09-11T22:32:24.446Z",
      "location_count": 1,
      "location_summary": "The Woodlands, Texas",
      "locations": [
        {
          "city": "The Woodlands",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02813161"
    }
  ]
}