{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Multimodal+optical+imaging",
    "query": {
      "intervention": "Multimodal optical imaging"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Multimodal+optical+imaging&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-05T19:31:08.855Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02773238",
      "title": "FLARE RT for Patients With Stage IIB-IIIB Non-small Cell Lung Cancer: Personalizing Radiation Therapy Using PET/CT and SPECT/CT Imaging",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Stage IIB Lung Non-Small Cell Carcinoma AJCC v7",
        "Stage IIIA Lung Non-Small Cell Cancer AJCC v7",
        "Stage IIIB Lung Non-Small Cell Cancer AJCC v7"
      ],
      "interventions": [
        {
          "name": "Computed Tomography",
          "type": "PROCEDURE"
        },
        {
          "name": "Fludeoxyglucose F-18",
          "type": "RADIATION"
        },
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "Positron Emission Tomography",
          "type": "PROCEDURE"
        },
        {
          "name": "Radiation Therapy",
          "type": "RADIATION"
        },
        {
          "name": "Single Photon Emission Computed Tomography",
          "type": "PROCEDURE"
        },
        {
          "name": "Technetium Tc-99m Albumin Aggregated",
          "type": "RADIATION"
        },
        {
          "name": "Technetium Tc-99m Sulfur Colloid",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "RADIATION",
        "OTHER"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 51,
      "start_date": "2016-05-20",
      "completion_date": "2023-12-01",
      "has_results": true,
      "last_update_posted_date": "2024-08-14",
      "last_synced_at": "2026-09-05T19:31:08.855Z",
      "location_count": 2,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02773238"
    },
    {
      "nct_id": "NCT01321892",
      "title": "Ex Vivo Multimodal Imaging of Upper Aerodigestive Epithelium",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Squamous Cell Carcinoma of the Oral Cavity",
        "Oropharynx",
        "Larynx",
        "Hypopharynx"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 64,
      "start_date": "2009-06",
      "completion_date": "2012-05",
      "has_results": false,
      "last_update_posted_date": "2012-06-21",
      "last_synced_at": "2026-09-05T19:31:08.855Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01321892"
    },
    {
      "nct_id": "NCT03233646",
      "title": "Retinal Imaging in Neurodegenerative Disease",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer's Disease",
        "Mild Cognitive Impairment",
        "Parkinson's Disease",
        "Multiple Sclerosis",
        "Huntington Disease",
        "Lewy Body Dementia",
        "Frontotemporal Dementia",
        "Amyotrophic Lateral Sclerosis (ALS)",
        "APOE-4 Positive",
        "Traumatic Brain Injury",
        "Concussion",
        "Post-Traumatic Stress Disorder",
        "Down Syndrome",
        "Neuro-Degenerative Disease",
        "Normal Cognition"
      ],
      "interventions": [
        {
          "name": "Retinal and Choroidal Imaging",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2000,
      "start_date": "2017-07-20",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-09-05T19:31:08.855Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03233646"
    },
    {
      "nct_id": "NCT01456143",
      "title": "Optical Imaging of Head and Neck Cancer",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Squamous Cell Carcinoma",
        "Neoplasia",
        "Head and Neck Cancer"
      ],
      "interventions": [
        {
          "name": "High Resolution Microendoscopy (HRME)",
          "type": "DEVICE"
        },
        {
          "name": "Proflavine hemisulfate",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Sharmila Anandasabapathy, MD",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 33,
      "start_date": "2011-12",
      "completion_date": "2014-07",
      "has_results": true,
      "last_update_posted_date": "2018-02-01",
      "last_synced_at": "2026-09-05T19:31:08.855Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01456143"
    },
    {
      "nct_id": "NCT05372484",
      "title": "Rice Technologies for Cervical Cancer Screening and Diagnosis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cervical Cancer"
      ],
      "interventions": [
        {
          "name": "Multimodal optical imaging",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "49 Years",
        "sex": "FEMALE",
        "summary": "25 Years to 49 Years · Female only"
      },
      "enrollment_count": 678,
      "start_date": "2021-03-24",
      "completion_date": "2028-03-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-10",
      "last_synced_at": "2026-09-05T19:31:08.855Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05372484"
    },
    {
      "nct_id": "NCT01982123",
      "title": "SPECT/CT in Measuring Lung Function in Patients With Cancer Undergoing Radiation Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lung Carcinoma",
        "Malignant Neoplasm"
      ],
      "interventions": [
        {
          "name": "SPECT/CT",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Single Photon Emission Computed Tomography",
          "type": "PROCEDURE"
        },
        {
          "name": "Technetium Tc-99m Albumin Aggregated",
          "type": "RADIATION"
        },
        {
          "name": "Technetium Tc-99m DTPA",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "PROCEDURE",
        "RADIATION",
        "DRUG"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2014-01-17",
      "completion_date": "2017-09-13",
      "has_results": true,
      "last_update_posted_date": "2018-12-13",
      "last_synced_at": "2026-09-05T19:31:08.855Z",
      "location_count": 2,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01982123"
    },
    {
      "nct_id": "NCT05784103",
      "title": "Comparison of Tissue Oxygenation Measurement Using Multimodal Devices",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Oxygen Saturation"
      ],
      "interventions": [
        {
          "name": "Clarifi Modulum",
          "type": "DEVICE"
        },
        {
          "name": "Perimed PeriFlux 5000",
          "type": "DEVICE"
        },
        {
          "name": "Apple Watch Oxygen Sensor",
          "type": "DEVICE"
        },
        {
          "name": "Innovo iP 900AP",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2022-03-09",
      "completion_date": "2022-07-07",
      "has_results": true,
      "last_update_posted_date": "2023-11-29",
      "last_synced_at": "2026-09-05T19:31:08.855Z",
      "location_count": 2,
      "location_summary": "Indianapolis, Indiana • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05784103"
    },
    {
      "nct_id": "NCT04458688",
      "title": "Investigating the Effect of Ocrelizumab in African Americans and Caucasians With Relapsing Multiple Sclerosis",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Multiple Sclerosis, Relapsing-Remitting"
      ],
      "interventions": [
        {
          "name": "Observation of Ocrelizumab as Treatment in RRMS Patients",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Wayne State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 80,
      "start_date": "2021-11-20",
      "completion_date": "2030-12",
      "has_results": false,
      "last_update_posted_date": "2022-06-06",
      "last_synced_at": "2026-09-05T19:31:08.855Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04458688"
    },
    {
      "nct_id": "NCT02790853",
      "title": "Multimodal Imaging for Surveillance in Patients With Oral Potentially Malignant Disorders",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Dysplasia",
        "Lip and Oral Cavity Carcinoma",
        "Oral Disorder",
        "Premalignant Lesion"
      ],
      "interventions": [
        {
          "name": "Biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "Fluorescence Imaging",
          "type": "PROCEDURE"
        },
        {
          "name": "High-Resolution Microendoscopy",
          "type": "PROCEDURE"
        },
        {
          "name": "Proflavine Hemisulfate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 63,
      "start_date": "2016-05-25",
      "completion_date": "2026-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-09-05T19:31:08.855Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02790853"
    },
    {
      "nct_id": "NCT03699644",
      "title": "Multimodal Ocular Imaging in Neurodegeneration",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Disease",
        "Alzheimer Dementia",
        "Frontotemporal Dementia"
      ],
      "interventions": [
        {
          "name": "Spectral-Domain Optical Coherence Tomography (SD-OCT)",
          "type": "DEVICE"
        },
        {
          "name": "Magnetic Resonance Imaging (MRI)",
          "type": "DEVICE"
        },
        {
          "name": "Positron Emission Tomography (PET)",
          "type": "DEVICE"
        },
        {
          "name": "Comprehensive Ophthalmic Examination",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Fundus Photography",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "45 Years to 80 Years"
      },
      "enrollment_count": 16,
      "start_date": "2019-01-04",
      "completion_date": "2019-04-03",
      "has_results": false,
      "last_update_posted_date": "2022-03-28",
      "last_synced_at": "2026-09-05T19:31:08.855Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03699644"
    }
  ]
}