{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=N+Acetyl+Cysteine&page=6", "query": { "intervention": "N Acetyl Cysteine", "page": 6 }, "page_size": 10 }, "pagination": { "page": 6, "page_size": 10, "total_count": 230, "total_pages": 23, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=N+Acetyl+Cysteine&page=7&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=N+Acetyl+Cysteine&page=5&page_size=10" }, "source": "remote", "last_synced_at": "2026-11-15T11:47:50.380Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01586533", "title": "Study of the Safety and Efficacy of Zoenasa® Versus Mesalamine Enema in Subjects With Left-Sided Ulcerative Colitis", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Ulcerative Colitis", "Left-sided Ulcerative Colitis", "Distal Ulcerative Colitis" ], "interventions": [ { "name": "Zoenasa-1:4", "type": "DRUG" }, { "name": "Mesalamine Enema", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Altheus Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "64 Years", "sex": "ALL", "summary": "18 Years to 64 Years" }, "enrollment_count": 120, "start_date": "2012-06", "completion_date": null, "has_results": false, "last_update_posted_date": "2014-01-08", "last_synced_at": "2026-11-15T11:47:50.380Z", "location_count": 45, "location_summary": "Birmingham, Alabama • Dothan, Alabama • Lakewood, Colorado + 39 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Dothan", "state": "Alabama" }, { "city": "Lakewood", "state": "Colorado" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Hialeah", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01586533" }, { "nct_id": "NCT01386645", "title": "Effect of Dietary Glycemic Index on Beta-cell Function", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Impaired Glucose Tolerance", "Oxidative Stress", "Prediabetes", "Impaired Fasting Glucose" ], "interventions": [ { "name": "low glycemic index (LGI) diet", "type": "OTHER" }, { "name": "high glycemic index (HGI) diet plus placebo (PLAC)", "type": "OTHER" }, { "name": "high glycemic index diet plus N-acetylcysteine", "type": "DRUG" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "Seattle Institute for Biomedical and Clinical Research", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 56, "start_date": "2011-07", "completion_date": "2019-08-01", "has_results": true, "last_update_posted_date": "2020-08-12", "last_synced_at": "2026-11-15T11:47:50.380Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT01386645" }, { "nct_id": "NCT03680911", "title": "NAC for Head Trauma-induced Anosmia", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Anosmia", "Head Trauma" ], "interventions": [ { "name": "N Acetyl Cysteine", "type": "DRUG" }, { "name": "Placebo oral capsule", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Miami", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 7, "start_date": "2018-10-12", "completion_date": "2020-01-07", "has_results": true, "last_update_posted_date": "2021-02-04", "last_synced_at": "2026-11-15T11:47:50.380Z", "location_count": 1, "location_summary": "Miami, Florida", "locations": [ { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03680911" }, { "nct_id": "NCT01320527", "title": "A Clinical Trial of a Vitamin/Nutriceutical Formulation for Alzheimer's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Alzheimer's Disease", "Mild Cognitive Impairment" ], "interventions": [ { "name": "Nutriceutical formulation", "type": "DIETARY_SUPPLEMENT" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DIETARY_SUPPLEMENT", "OTHER" ], "sponsor": "University of Massachusetts, Worcester", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 135, "start_date": "2008-08", "completion_date": "2012-04", "has_results": false, "last_update_posted_date": "2016-03-03", "last_synced_at": "2026-11-15T11:47:50.380Z", "location_count": 8, "location_summary": "Naples, Florida • Baltimore, Maryland • Ayer, Massachusetts + 5 more", "locations": [ { "city": "Naples", "state": "Florida" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Ayer", "state": "Massachusetts" }, { "city": "Groton", "state": "Massachusetts" }, { "city": "Lawrence", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01320527" }, { "nct_id": "NCT02911285", "title": "NAC for Treating Comorbid PTSD and SUD", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Posttraumatic Stress Disorder (PTSD)", "Alcohol Use Disorder (AUD)", "Substance Use Disorder (SUD)" ], "interventions": [ { "name": "N-acetylcysteine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Cognitive behavioral therapy", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 90, "start_date": "2016-10", "completion_date": "2019-11-04", "has_results": true, "last_update_posted_date": "2021-05-19", "last_synced_at": "2026-11-15T11:47:50.380Z", "location_count": 2, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" }, { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02911285" }, { "nct_id": "NCT01797575", "title": "N-Acetyl Cysteine and Aspirin as an Adjunctive Treatment for Bipolar Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "Aspirin", "type": "DRUG" }, { "name": "N-acetyl-cysteine (NAC)", "type": "DIETARY_SUPPLEMENT" }, { "name": "Sugar Pill", "type": "DRUG" } ], "intervention_types": [ "DRUG", "DIETARY_SUPPLEMENT" ], "sponsor": "The University of Texas Health Science Center, Houston", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 38, "start_date": "2013-01", "completion_date": "2017-02-01", "has_results": true, "last_update_posted_date": "2018-04-30", "last_synced_at": "2026-11-15T11:47:50.380Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01797575" }, { "nct_id": "NCT00205647", "title": "Study of Expectorant Activity of Oral N-acetylcystein (NAC) in Patients With Stable Chronic Bronchitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Bronchitis" ], "interventions": [ { "name": "Oral N-acetycystein (NAC)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Wake Forest University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 240, "start_date": "1997-01", "completion_date": "2000-03", "has_results": false, "last_update_posted_date": "2017-11-06", "last_synced_at": "2026-11-15T11:47:50.380Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00205647" }, { "nct_id": "NCT03911414", "title": "A Clinical Trial Via Telepsychiatry of Treatments for the Management of Emotional Dysregulation in Youth", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Mood Disturbance", "Mood Disorders", "Natural Supplements", "Alternative Treatment" ], "interventions": [ { "name": "Open-label Treatment with Omega-3 Fatty Acids + Inositol", "type": "DRUG" }, { "name": "Open-label Treatment with N-acetylcysteine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "5 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "5 Years to 17 Years" }, "enrollment_count": 27, "start_date": "2019-06-18", "completion_date": "2024-12-04", "has_results": true, "last_update_posted_date": "2026-03-18", "last_synced_at": "2026-11-15T11:47:50.380Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT03911414" }, { "nct_id": "NCT01005810", "title": "A Trial of N-Acetylcysteine (an Over-the-Counter Medicine) in Adolescents Who Smoke Marijuana", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Cannabis Dependence" ], "interventions": [ { "name": "N-Acetylcysteine", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" }, { "name": "Contingency Management", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "13 Years to 21 Years" }, "enrollment_count": 116, "start_date": "2009-09", "completion_date": "2011-08", "has_results": true, "last_update_posted_date": "2018-11-21", "last_synced_at": "2026-11-15T11:47:50.380Z", "location_count": 1, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01005810" }, { "nct_id": "NCT02171104", "title": "MT2013-31: Allo HCT for Metabolic Disorders and Severe Osteopetrosis", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Mucopolysaccharidosis Disorders", "Hurler Syndrome", "Hunter Syndrome", "Maroteaux Lamy Syndrome", "Sly Syndrome", "Alpha-Mannosidosis", "Fucosidosis", "Aspartylglucosaminuria", "Glycoprotein Metabolic Disorders", "Sphingolipidoses", "Recessive Leukodystrophies", "Globoid Cell Leukodystrophy", "Metachromatic Leukodystrophy", "Niemann-Pick B", "Niemann-Pick C Subtype 2", "Sphingomyelin Deficiency", "Peroxisomal Disorders", "Adrenoleukodystrophy With Cerebral Involvement", "Zellweger Syndrome", "Neonatal Adrenoleukodystrophy", "Infantile Refsum Disease", "Acyl-CoA Oxidase Deficiency", "D-Bifunctional Enzyme Deficiency", "Multifunctional Enzyme Deficiency", "Alpha-methylacyl-CoA Racmase Deficiency", "Mitochondrial Neurogastrointestingal Encephalopathy", "Severe Osteopetrosis", "Hereditary Leukoencephalopathy With Axonal Spheroids (HDLS; CSF1R Mutation)", "Inherited Metabolic Disorders" ], "interventions": [ { "name": "Stem Cell Transplantation", "type": "BIOLOGICAL" }, { "name": "IMD Preparative Regimen", "type": "DRUG" }, { "name": "Osteopetrosis Only Preparative Regimen", "type": "DRUG" }, { "name": "Osteopetrosis Haploidentical Only Preparative Regimen", "type": "DRUG" }, { "name": "cALD SR-A (Standard-Risk, Regimen A)", "type": "DRUG" }, { "name": "cALD SR-B (Standard-Risk, Regimen B)", "type": "DRUG" }, { "name": "cALD HR-D (High-Risk, Regimen C)", "type": "DRUG" }, { "name": "cALD HR-D (High-Risk, Regimen D)", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Masonic Cancer Center, University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "55 Years", "sex": "ALL", "summary": "Up to 55 Years" }, "enrollment_count": 149, "start_date": "2014-07-10", "completion_date": "2031-07-14", "has_results": false, "last_update_posted_date": "2026-11-03", "last_synced_at": "2026-11-15T11:47:50.380Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT02171104" } ] }