{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=N+Acetyl+Cysteine&page=9",
    "query": {
      "intervention": "N Acetyl Cysteine",
      "page": 9
    },
    "page_size": 10
  },
  "pagination": {
    "page": 9,
    "page_size": 10,
    "total_count": 230,
    "total_pages": 23,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=N+Acetyl+Cysteine&page=10&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=N+Acetyl+Cysteine&page=8&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T13:04:29.992Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01537926",
      "title": "Hypertrophic Regression With N-Acetylcysteine in HCM",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hypertrophic Cardiomyopathy"
      ],
      "interventions": [
        {
          "name": "N-acetylcysteine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 42,
      "start_date": "2012-01",
      "completion_date": "2016-12-31",
      "has_results": true,
      "last_update_posted_date": "2021-11-02",
      "last_synced_at": "2026-11-15T13:04:29.992Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01537926"
    },
    {
      "nct_id": "NCT01232790",
      "title": "A Pilot Trial of Acute N-Acetylcysteine Effects on Working Memory and Other Cognitive Functions in Schizophrenia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Schizophrenia"
      ],
      "interventions": [
        {
          "name": "N-Acetylcysteine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 28,
      "start_date": "2010-02",
      "completion_date": "2011-11",
      "has_results": true,
      "last_update_posted_date": "2015-12-01",
      "last_synced_at": "2026-11-15T13:04:29.992Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01232790"
    },
    {
      "nct_id": "NCT01265563",
      "title": "N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetic Nephropathy",
        "Proteinuria",
        "Oxidative Stress"
      ],
      "interventions": [
        {
          "name": "N-acetylcysteine placebo and silibin placebo",
          "type": "DRUG"
        },
        {
          "name": "N-acetylcysteine active and silibin placebo",
          "type": "DRUG"
        },
        {
          "name": "N-acetylcysteine placebo and silibin active",
          "type": "DRUG"
        },
        {
          "name": "N-acetylcysteine active and silibin active",
          "type": "DRUG"
        },
        {
          "name": "N-acetylcysteine active + high-dose silibin active",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "76 Years",
        "sex": "ALL",
        "summary": "18 Years to 76 Years"
      },
      "enrollment_count": 108,
      "start_date": "2011-01",
      "completion_date": "2016-12",
      "has_results": true,
      "last_update_posted_date": "2018-10-19",
      "last_synced_at": "2026-11-15T13:04:29.992Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01265563"
    },
    {
      "nct_id": "NCT04117022",
      "title": "Diabetic Retinopathy Functional Evaluation Study: Monitoring Carotenoid Vitamins Treatment Using ERG",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes",
        "Diabetic Retinopathy"
      ],
      "interventions": [
        {
          "name": "DVS supplementation",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "ZeaVision, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 45,
      "start_date": "2019-09-01",
      "completion_date": "2022-12-01",
      "has_results": false,
      "last_update_posted_date": "2021-04-23",
      "last_synced_at": "2026-11-15T13:04:29.992Z",
      "location_count": 2,
      "location_summary": "Pomona, California • Tahlequah, Oklahoma",
      "locations": [
        {
          "city": "Pomona",
          "state": "California"
        },
        {
          "city": "Tahlequah",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04117022"
    },
    {
      "nct_id": "NCT01878695",
      "title": "Pilot Study of Anti-oxidant Supplementation With N-Acetyl Cysteine in Stage 0/I Breast Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Stage 0/1 Breast Cancer",
        "Post Biopsy",
        "Pre-surgery"
      ],
      "interventions": [
        {
          "name": "IV/oral n-acetylcysteine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 13,
      "start_date": "2012-07-26",
      "completion_date": "2015-05-14",
      "has_results": false,
      "last_update_posted_date": "2025-05-02",
      "last_synced_at": "2026-11-15T13:04:29.992Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01878695"
    },
    {
      "nct_id": "NCT00724594",
      "title": "Safety of N-acetylcysteine in Maternal Chorioamnionitis (NAC in Chorio)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Chorioamnionitis",
        "Brain Injury"
      ],
      "interventions": [
        {
          "name": "N-acetylcysteine",
          "type": "DRUG"
        },
        {
          "name": "Control",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "13 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2008-08",
      "completion_date": "2014-08",
      "has_results": true,
      "last_update_posted_date": "2021-04-12",
      "last_synced_at": "2026-11-15T13:04:29.992Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00724594"
    },
    {
      "nct_id": "NCT00434005",
      "title": "Effect of Diesel Exhaust Particulate Exposures on Endothelial Function in Humans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "N-acetylcysteine, ascorbate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "18 Years to 49 Years"
      },
      "enrollment_count": 24,
      "start_date": "2008-07",
      "completion_date": "2010-08",
      "has_results": false,
      "last_update_posted_date": "2013-01-16",
      "last_synced_at": "2026-11-15T13:04:29.992Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00434005"
    },
    {
      "nct_id": "NCT01424033",
      "title": "A Clinical Trial for CTD-ILD Treatment",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Interstitial Lung Disease",
        "Connective Tissue Disease"
      ],
      "interventions": [
        {
          "name": "N-Acetylcysteine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2011-12",
      "completion_date": null,
      "has_results": true,
      "last_update_posted_date": "2017-04-06",
      "last_synced_at": "2026-11-15T13:04:29.992Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01424033"
    },
    {
      "nct_id": "NCT00568087",
      "title": "N-acetylcysteine in Alcohol Dependence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Alcoholism"
      ],
      "interventions": [
        {
          "name": "N-acetylcysteine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Minneapolis Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 46,
      "start_date": "2007-12",
      "completion_date": "2009-08",
      "has_results": true,
      "last_update_posted_date": "2020-03-18",
      "last_synced_at": "2026-11-15T13:04:29.992Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00568087"
    },
    {
      "nct_id": "NCT01381354",
      "title": "Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "Progressive exercise",
          "type": "OTHER"
        },
        {
          "name": "Neuromuscular electrical stimulation delivered using the electrical therapy device EMPI 300 PV",
          "type": "DEVICE"
        },
        {
          "name": "Modified paleolithic diet",
          "type": "OTHER"
        },
        {
          "name": "Omega 3 fatty acids",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Full Spectrum vitamin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Essential - hydroxytyrosol",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Maltodextrin fiber supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Mineral boost (magnesium)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Niacinamide",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Methyl B12",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Taurine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "creatine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "thiamine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "riboflavin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "N acetylcysteine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "alpha lipoic acid",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "L acetyl carnitine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "methyl folate",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "coenzyme Q",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "meditation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "self massage",
          "type": "BEHAVIORAL"
        },
        {
          "name": "learning",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Coconut oil",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE",
        "DIETARY_SUPPLEMENT",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 38,
      "start_date": "2010-10",
      "completion_date": "2016-05",
      "has_results": false,
      "last_update_posted_date": "2018-06-26",
      "last_synced_at": "2026-11-15T13:04:29.992Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01381354"
    }
  ]
}