{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=NNC0487-0111", "query": { "intervention": "NNC0487-0111" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 13, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=NNC0487-0111&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-07T08:26:10.312Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07571109", "title": "AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Obesity", "Overweight", "Obstructive Sleep Apnoea" ], "interventions": [ { "name": "NNC0487-0111", "type": "DRUG" }, { "name": "Placebo (matched to NNC0487-0111)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novo Nordisk A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 300, "start_date": "2026-05-05", "completion_date": "2028-08-21", "has_results": false, "last_update_posted_date": "2026-05-22", "last_synced_at": "2026-06-07T08:26:10.312Z", "location_count": 20, "location_summary": "Gilbert, Arizona • Bradenton, Florida • Naples, Florida + 16 more", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Bradenton", "state": "Florida" }, { "city": "Naples", "state": "Florida" }, { "city": "West Palm Beach", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT07571109" }, { "nct_id": "NCT07509307", "title": "AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Obesity", "Overweight", "Osteoarthritis, Knee" ], "interventions": [ { "name": "NNC0487-0111", "type": "DRUG" }, { "name": "Placebo (matched to NNC0487-0111)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novo Nordisk A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 400, "start_date": "2026-04-20", "completion_date": "2028-08-14", "has_results": false, "last_update_posted_date": "2026-06-02", "last_synced_at": "2026-06-07T08:26:10.312Z", "location_count": 19, "location_summary": "Escondido, California • Lancaster, California • Palm Springs, California + 14 more", "locations": [ { "city": "Escondido", "state": "California" }, { "city": "Lancaster", "state": "California" }, { "city": "Palm Springs", "state": "California" }, { "city": "Waterbury", "state": "Connecticut" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07509307" }, { "nct_id": "NCT06064006", "title": "A Research Study to See How a New Medicine (NNC0487-0111) Works in People With Overweight or Obesity When Injected Under the Skin", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Obesity", "Overweight" ], "interventions": [ { "name": "NNC0487-0111", "type": "DRUG" }, { "name": "Placebo (NNC0487-0111)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novo Nordisk A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 125, "start_date": "2023-09-15", "completion_date": "2024-11-27", "has_results": false, "last_update_posted_date": "2025-11-19", "last_synced_at": "2026-06-07T08:26:10.312Z", "location_count": 2, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06064006" }, { "nct_id": "NCT07400107", "title": "AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Obesity", "Overweight", "Diabetes Mellitus, Type 2" ], "interventions": [ { "name": "NNC0487-0111", "type": "DRUG" }, { "name": "Semaglutide", "type": "DRUG" }, { "name": "Placebo (matched to NNC0487-0111)", "type": "DRUG" }, { "name": "Placebo (matched to semaglutide)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novo Nordisk A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1000, "start_date": "2026-05-20", "completion_date": "2029-01-26", "has_results": false, "last_update_posted_date": "2026-03-12", "last_synced_at": "2026-06-07T08:26:10.312Z", "location_count": 10, "location_summary": "Hollywood, Florida • Orange City, Florida • Weston, Florida + 7 more", "locations": [ { "city": "Hollywood", "state": "Florida" }, { "city": "Orange City", "state": "Florida" }, { "city": "Weston", "state": "Florida" }, { "city": "Roswell", "state": "Georgia" }, { "city": "Blackfoot", "state": "Idaho" } ], "official_url": "https://clinicaltrials.gov/study/NCT07400107" }, { "nct_id": "NCT05369390", "title": "A Research Study on How NNC0487-0111 Works in People With Overweight or Obesity", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Obesity" ], "interventions": [ { "name": "NNC0487-0111 A", "type": "DRUG" }, { "name": "NNC0487-0111 B", "type": "DRUG" }, { "name": "Placebo B (NNC0487-0111 B)", "type": "OTHER" }, { "name": "Placebo A (NNC0487-0111 A)", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Novo Nordisk A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 144, "start_date": "2022-05-11", "completion_date": "2024-01-09", "has_results": false, "last_update_posted_date": "2025-06-15", "last_synced_at": "2026-06-07T08:26:10.312Z", "location_count": 2, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05369390" }, { "nct_id": "NCT07571005", "title": "AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Obesity", "Overweight", "Obstructive Sleep Apnoea" ], "interventions": [ { "name": "NNC0487-0111", "type": "DRUG" }, { "name": "Placebo (matched to NNC0487-0111)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novo Nordisk A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 300, "start_date": "2026-05-05", "completion_date": "2028-10-04", "has_results": false, "last_update_posted_date": "2026-06-02", "last_synced_at": "2026-06-07T08:26:10.312Z", "location_count": 17, "location_summary": "San Diego, California • Miami, Florida • Naples, Florida + 13 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Naples", "state": "Florida" }, { "city": "Ocala", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT07571005" }, { "nct_id": "NCT06478563", "title": "A Research Study Looking at Different Oral Formulations and the Effect of Food Intake on How the Medicine NNC0487-0111 Behaves in the Body of Participants Living With Overweight or Obesity", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Obesity", "Overweight" ], "interventions": [ { "name": "NNC0487-0111 (formulation D)", "type": "DRUG" }, { "name": "NNC0487-0111 (formulation C)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novo Nordisk A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "64 Years", "sex": "ALL", "summary": "18 Years to 64 Years" }, "enrollment_count": 133, "start_date": "2024-06-27", "completion_date": "2025-07-01", "has_results": false, "last_update_posted_date": "2025-08-11", "last_synced_at": "2026-06-07T08:26:10.312Z", "location_count": 1, "location_summary": "Lincoln, Nebraska", "locations": [ { "city": "Lincoln", "state": "Nebraska" } ], "official_url": "https://clinicaltrials.gov/study/NCT06478563" }, { "nct_id": "NCT07533175", "title": "AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Diabetes Mellitus", "Overweight", "Obesity" ], "interventions": [ { "name": "NNC0487-0111", "type": "DRUG" }, { "name": "Placebo (matched to NNC0487-0111)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novo Nordisk A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 630, "start_date": "2026-04-13", "completion_date": "2028-08-07", "has_results": false, "last_update_posted_date": "2026-06-02", "last_synced_at": "2026-06-07T08:26:10.312Z", "location_count": 15, "location_summary": "Birmingham, Alabama • Escondido, California • Lomita, California + 12 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Escondido", "state": "California" }, { "city": "Lomita", "state": "California" }, { "city": "Walnut Creek", "state": "California" }, { "city": "Fleming Island", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07533175" }, { "nct_id": "NCT06542874", "title": "A Research Study Comparing How Well Different Doses of the Medicine NNC0487-0111 Lower Blood Sugar in People With Type 2 Diabetes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Type 2 Diabetes (T2D)" ], "interventions": [ { "name": "NNC0487-0111 subcutanous", "type": "DRUG" }, { "name": "Placebo (NNC0487-0111 subcutanous)", "type": "DRUG" }, { "name": "NNC0487-0111 oral", "type": "DRUG" }, { "name": "Placebo (NNC0487-0111 oral)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novo Nordisk A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 448, "start_date": "2024-08-07", "completion_date": "2025-10-24", "has_results": false, "last_update_posted_date": "2025-12-29", "last_synced_at": "2026-06-07T08:26:10.312Z", "location_count": 28, "location_summary": "Santa Ana, California • Waterbury, Connecticut • Fleming Island, Florida + 21 more", "locations": [ { "city": "Santa Ana", "state": "California" }, { "city": "Waterbury", "state": "Connecticut" }, { "city": "Fleming Island", "state": "Florida" }, { "city": "Hollywood", "state": "Florida" }, { "city": "Miramar", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06542874" }, { "nct_id": "NCT07503210", "title": "AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Obesity" ], "interventions": [ { "name": "NNC0487-0111", "type": "DRUG" }, { "name": "Placebo (matched to NNC0487-0111)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novo Nordisk A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 600, "start_date": "2026-04-21", "completion_date": "2028-07-04", "has_results": false, "last_update_posted_date": "2026-06-02", "last_synced_at": "2026-06-07T08:26:10.312Z", "location_count": 13, "location_summary": "Anniston, Alabama • Walnut Creek, California • Orlando, Florida + 9 more", "locations": [ { "city": "Anniston", "state": "Alabama" }, { "city": "Walnut Creek", "state": "California" }, { "city": "Orlando", "state": "Florida" }, { "city": "Skokie", "state": "Illinois" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT07503210" } ] }