{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=NPWT",
    "query": {
      "intervention": "NPWT"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 138,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=NPWT&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T05:33:37.848Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03180346",
      "title": "A Prospective, Randomized, Comparative Study to Assess the Prevention of Surgical Site Infection (SSI's) in Revision Total Joint Arthroplasty Patients Treated With Single-Use Negative Pressure Wound Therapy (PICO) or Standard Care Dressings (AQUACEL Ag SURGICAL Dressing).",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgical Incision"
      ],
      "interventions": [
        {
          "name": "PICO",
          "type": "DEVICE"
        },
        {
          "name": "Aquacel",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Rothman Institute Orthopaedics",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 494,
      "start_date": "2017-03-21",
      "completion_date": "2021-03",
      "has_results": false,
      "last_update_posted_date": "2017-06-08",
      "last_synced_at": "2026-09-06T05:33:37.848Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03180346"
    },
    {
      "nct_id": "NCT00724750",
      "title": "Comparison of Two Methods of Negative Pressure Wound Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Wounds From Trauma",
        "Dehiscence or Surgical Complications"
      ],
      "interventions": [
        {
          "name": "Gauze suction (G-SUC)",
          "type": "DEVICE"
        },
        {
          "name": "Vacuum Assisted Closure Device (VAC)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 87,
      "start_date": "2006-07",
      "completion_date": "2008-05",
      "has_results": true,
      "last_update_posted_date": "2015-10-19",
      "last_synced_at": "2026-09-06T05:33:37.848Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00724750"
    },
    {
      "nct_id": "NCT02813161",
      "title": "The Diabetic Foot Ulcer Registry",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetic Foot Ulcer Outcome",
        "Quality of Patient Care"
      ],
      "interventions": [
        {
          "name": "cellular and tissue based therapy",
          "type": "BIOLOGICAL"
        },
        {
          "name": "negative pressure wound therapy",
          "type": "DEVICE"
        },
        {
          "name": "debridement",
          "type": "PROCEDURE"
        },
        {
          "name": "advanced wound therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Nutritional screening",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "off-loading",
          "type": "DEVICE"
        },
        {
          "name": "Hyperbaric oxygen Therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DEVICE",
        "PROCEDURE",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "U.S. Wound Registry",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 10000,
      "start_date": "2015-02",
      "completion_date": "2025-02",
      "has_results": false,
      "last_update_posted_date": "2018-05-03",
      "last_synced_at": "2026-09-06T05:33:37.848Z",
      "location_count": 1,
      "location_summary": "The Woodlands, Texas",
      "locations": [
        {
          "city": "The Woodlands",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02813161"
    },
    {
      "nct_id": "NCT04026334",
      "title": "Evaluation of V.A.C. VERAFLO CLEANSE CHOICE™ Dressing Using Normal Saline to Promote Increased Healthy Wound Bed Tissue",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wound",
        "Wound Heal",
        "Wounds and Injuries",
        "Granulation Tissue",
        "Negative-pressure Wound Therapy"
      ],
      "interventions": [
        {
          "name": "V.A.C. VERAFLO CLEANSE CHOICE™ dressing with Normal Saline",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "3M",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2019-07-25",
      "completion_date": "2020-08-28",
      "has_results": false,
      "last_update_posted_date": "2022-08-01",
      "last_synced_at": "2026-09-06T05:33:37.848Z",
      "location_count": 1,
      "location_summary": "Augusta, Georgia",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04026334"
    },
    {
      "nct_id": "NCT07032701",
      "title": "A Disposable Negative Pressure Wound Therapy Device (SNaP) to Promote Wound Healing in the Lower Limbs Following Mohs Micrographic Surgery for Non-melanoma Skin Cancer",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Skin Carcinoma"
      ],
      "interventions": [
        {
          "name": "Best Practice",
          "type": "OTHER"
        },
        {
          "name": "Educational Intervention",
          "type": "OTHER"
        },
        {
          "name": "Electronic Health Record Review",
          "type": "OTHER"
        },
        {
          "name": "Follow-Up Care",
          "type": "OTHER"
        },
        {
          "name": "Medical Device Usage and Evaluation",
          "type": "OTHER"
        },
        {
          "name": "Negative Pressure Wound Therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Photography",
          "type": "OTHER"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Jonsson Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "19 Years to 79 Years"
      },
      "enrollment_count": 60,
      "start_date": "2026-12",
      "completion_date": "2031-06",
      "has_results": false,
      "last_update_posted_date": "2026-07-01",
      "last_synced_at": "2026-09-06T05:33:37.848Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07032701"
    },
    {
      "nct_id": "NCT07653165",
      "title": "Use of Hydroprep Wound Therapy With Motion Negative Pressure Therapy for Treatment of Chronic Lower Extremity Wounds",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Lower Leg Ulcer",
        "Diabetic Lower Extremity Ulcers",
        "Pressure Injuries",
        "Traumatic Wounds and Injuries",
        "Surgical Wounds"
      ],
      "interventions": [
        {
          "name": "Motion NPWT",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "West Boca Center for Wound Healing",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 50,
      "start_date": "2026-04-15",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-17",
      "last_synced_at": "2026-09-06T05:33:37.848Z",
      "location_count": 1,
      "location_summary": "Coconut Creek, Florida",
      "locations": [
        {
          "city": "Coconut Creek",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07653165"
    },
    {
      "nct_id": "NCT05169814",
      "title": "Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Open Wound",
        "Wound Heal"
      ],
      "interventions": [
        {
          "name": "Micro/nanobubble (MNB) - Irrigation",
          "type": "DRUG"
        },
        {
          "name": "0.9% Normal Saline - Irrigation",
          "type": "OTHER"
        },
        {
          "name": "Micro/nanobubble (MNB) - Negative Pressure Wound Therapy with Instillation (NPWTi)",
          "type": "DRUG"
        },
        {
          "name": "0.9% Normal Saline - Negative Pressure Wound Therapy with Instillation (NPWTi)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2021-10-09",
      "completion_date": "2027-06-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-02",
      "last_synced_at": "2026-09-06T05:33:37.848Z",
      "location_count": 1,
      "location_summary": "Orange, California",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05169814"
    },
    {
      "nct_id": "NCT02127281",
      "title": "Evaluation of Wound Management With Negative Pressure Dressing Versus Standard Dressing After Revision Arthroplasty.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prosthesis-related Infections",
        "Wound Complications",
        "Joint Diseases",
        "Musculoskeletal Diseases"
      ],
      "interventions": [
        {
          "name": "Prevena",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2014-05",
      "completion_date": "2017-06-30",
      "has_results": true,
      "last_update_posted_date": "2018-09-19",
      "last_synced_at": "2026-09-06T05:33:37.848Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02127281"
    },
    {
      "nct_id": "NCT02519192",
      "title": "The Role of VAC Therapy Devices in Promoting Closure of Enterocutaneous Fistulae",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fistulae"
      ],
      "interventions": [
        {
          "name": "V.A.C.Ulta™ Negative Pressure Wound Therapy System",
          "type": "DEVICE"
        },
        {
          "name": "Vac sponge irrigations",
          "type": "PROCEDURE"
        },
        {
          "name": "ostomy bag",
          "type": "PROCEDURE"
        },
        {
          "name": "wet to dry dressings",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Denver Health and Hospital Authority",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2016-01",
      "completion_date": "2017-01",
      "has_results": false,
      "last_update_posted_date": "2018-01-03",
      "last_synced_at": "2026-09-06T05:33:37.848Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02519192"
    },
    {
      "nct_id": "NCT00582998",
      "title": "Vacuum Assisted Closure as a Treatment for Soft Tissue Injuries",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fracture of Calcaneus, Pilon or Tibial Plateau"
      ],
      "interventions": [
        {
          "name": "Standard Wound Dressing",
          "type": "PROCEDURE"
        },
        {
          "name": "Vacuum Assisted Closure Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 249,
      "start_date": "2001-06",
      "completion_date": "2007-03",
      "has_results": true,
      "last_update_posted_date": "2019-07-25",
      "last_synced_at": "2026-09-06T05:33:37.848Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00582998"
    }
  ]
}