{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=NaF&page=5",
    "query": {
      "intervention": "NaF",
      "page": 5
    },
    "page_size": 10
  },
  "pagination": {
    "page": 5,
    "page_size": 10,
    "total_count": 219,
    "total_pages": 22,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=NaF&page=6&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=NaF&page=4&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-20T09:51:23.468Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02169063",
      "title": "Carbon-11 Acetate and Fluorine F 18 Sodium Fluoride PET as a Biomarker of Treatment Response in Patients With Hormone Resistant Metastatic Prostate Cancer",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hormone-resistant Prostate Cancer",
        "Recurrent Prostate Cancer",
        "Stage IV Prostate Cancer"
      ],
      "interventions": [
        {
          "name": "carbon-11 acetate",
          "type": "RADIATION"
        },
        {
          "name": "fluorine F 18 sodium fluoride",
          "type": "RADIATION"
        },
        {
          "name": "positron emission tomography",
          "type": "PROCEDURE"
        },
        {
          "name": "laboratory biomarker analysis",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "RADIATION",
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 0,
      "start_date": "2015-12",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2016-08-31",
      "last_synced_at": "2026-10-20T09:51:23.468Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02169063"
    },
    {
      "nct_id": "NCT04206319",
      "title": "Radium-223 in Biochemically Recurrent Prostate Cancer",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Biochemical Recurrent Prostate Cancer"
      ],
      "interventions": [
        {
          "name": "Radium-223",
          "type": "DRUG"
        },
        {
          "name": "18F Sodium Fluoride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "120 Years",
        "sex": "MALE",
        "summary": "18 Years to 120 Years · Male only"
      },
      "enrollment_count": 19,
      "start_date": "2020-09-22",
      "completion_date": "2026-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-16",
      "last_synced_at": "2026-10-20T09:51:23.468Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04206319"
    },
    {
      "nct_id": "NCT03388619",
      "title": "Highly Conformal, Hypofractionated, Focally Dose Escalated Post-Prostatectomy Radiotherapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Cancer Of Prostate",
        "Prostate Neoplasms",
        "Prostate Cancer",
        "Neoplasms of Prostate",
        "Prostatic Cancer"
      ],
      "interventions": [
        {
          "name": "Prostate bed with integrated boost",
          "type": "RADIATION"
        },
        {
          "name": "Prostate bed irradiation only",
          "type": "RADIATION"
        },
        {
          "name": "Whole Body Bone Scan",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "18F-NaF PET Imaging",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "CT",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "mpMRI",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "ADT",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "RADIATION",
        "DIAGNOSTIC_TEST",
        "DRUG"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 30,
      "start_date": "2018-01-17",
      "completion_date": "2025-12-04",
      "has_results": true,
      "last_update_posted_date": "2026-08-28",
      "last_synced_at": "2026-10-20T09:51:23.468Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03388619"
    },
    {
      "nct_id": "NCT02127073",
      "title": "Pilot Study of Oxytocin and microRNA Identification in NAF, Serum, and Tissue in Women With Breast Cancer",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Breast Cancer",
        "Ductal Carcinoma in Situ"
      ],
      "interventions": [
        {
          "name": "Intranasal Oxytocin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 8,
      "start_date": "2015-01-30",
      "completion_date": "2017-09-18",
      "has_results": true,
      "last_update_posted_date": "2023-11-09",
      "last_synced_at": "2026-10-20T09:51:23.468Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02127073"
    },
    {
      "nct_id": "NCT04125862",
      "title": "Pain in Fibrous Dysplasia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fibrous Dysplasia/McCune-Albright Syndrome"
      ],
      "interventions": [
        {
          "name": "MRI-based Neuroimaging",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Non-contrast MRI",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "18F-FDG-PET/CT",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "18F-NaF-PET/CT",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "10 Years to 45 Years"
      },
      "enrollment_count": 37,
      "start_date": "2021-01-05",
      "completion_date": "2025-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-12-11",
      "last_synced_at": "2026-10-20T09:51:23.468Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04125862"
    },
    {
      "nct_id": "NCT06010758",
      "title": "A Two-Week Study of an Anticavity Low pH Mouthwash",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Listerine Experimental Mouthwash",
          "type": "DRUG"
        },
        {
          "name": "Colgate Cavity Protection Toothpaste",
          "type": "DRUG"
        },
        {
          "name": "Listerine Total Care Zero",
          "type": "DRUG"
        },
        {
          "name": "Listerine Cool Mint Zero",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Johnson & Johnson Consumer Inc. (J&JCI)",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 163,
      "start_date": "2023-07-17",
      "completion_date": "2023-08-03",
      "has_results": false,
      "last_update_posted_date": "2024-01-12",
      "last_synced_at": "2026-10-20T09:51:23.468Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06010758"
    },
    {
      "nct_id": "NCT00759031",
      "title": "Investigation of Dental Plaque and Gingival Index",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dental Plaque"
      ],
      "interventions": [
        {
          "name": "Sodium Monofluorophosphate",
          "type": "DRUG"
        },
        {
          "name": "Triclosan/Fluoride/Copolymer",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 19,
      "start_date": "2008-02",
      "completion_date": "2008-03",
      "has_results": true,
      "last_update_posted_date": "2012-04-13",
      "last_synced_at": "2026-10-20T09:51:23.468Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00759031"
    },
    {
      "nct_id": "NCT04696536",
      "title": "A Twelve Week Study of Supervised Mouth Rinse and Flossing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Colgate Cavity Protection Toothpaste",
          "type": "OTHER"
        },
        {
          "name": "American Dental Association (ADA) Referenced Toothbrush",
          "type": "OTHER"
        },
        {
          "name": "5% Hydroalcohol Mouth Rinse",
          "type": "OTHER"
        },
        {
          "name": "REACH Dental Floss",
          "type": "OTHER"
        },
        {
          "name": "Alcohol-containing Essential Oil (AEO) Mouth Rinse (Listerine Cool Mint, marketed)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johnson & Johnson Consumer Inc. (J&JCI)",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 149,
      "start_date": "2018-09-26",
      "completion_date": "2018-12-21",
      "has_results": false,
      "last_update_posted_date": "2021-09-28",
      "last_synced_at": "2026-10-20T09:51:23.468Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04696536"
    },
    {
      "nct_id": "NCT06182267",
      "title": "Maximal Use Study to Determine the Pharmacokinetics of L-arginine After Exaggerated Oral Use of COL101",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Caries,Dental"
      ],
      "interventions": [
        {
          "name": "L Arginine",
          "type": "DRUG"
        },
        {
          "name": "Sodium Fluoride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 29,
      "start_date": "2023-11-27",
      "completion_date": "2023-12-22",
      "has_results": false,
      "last_update_posted_date": "2024-01-02",
      "last_synced_at": "2026-10-20T09:51:23.468Z",
      "location_count": 1,
      "location_summary": "Fair Lawn, New Jersey",
      "locations": [
        {
          "city": "Fair Lawn",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06182267"
    },
    {
      "nct_id": "NCT07556367",
      "title": "Post-Radiation Oral Health in Underserved Head and Neck Cancer Patients",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Head and Neck Cancer",
        "Head and Neck Carcinoma",
        "Head and Neck Neoplasms"
      ],
      "interventions": [
        {
          "name": "Surveys",
          "type": "OTHER"
        },
        {
          "name": "Saliva Collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Intra-oral photographs",
          "type": "PROCEDURE"
        },
        {
          "name": "Fluoride Varnish Treatment",
          "type": "DEVICE"
        },
        {
          "name": "Interview (Participant)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 43,
      "start_date": "2024-10-01",
      "completion_date": "2026-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-01",
      "last_synced_at": "2026-10-20T09:51:23.468Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07556367"
    }
  ]
}