{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Naloxone+2+MG&page=3", "query": { "intervention": "Naloxone 2 MG", "page": 3 }, "page_size": 10 }, "pagination": { "page": 3, "page_size": 10, "total_count": 136, "total_pages": 14, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Naloxone+2+MG&page=4&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Naloxone+2+MG&page=2&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-09T09:07:03.730Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00249574", "title": "Bridging Active Heroin Users to Hepatitis C Treatment Using Buprenorphine - 1", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hepatitis C", "Heroin Dependence" ], "interventions": [ { "name": "Buprenorphine/naloxone", "type": "DRUG" }, { "name": "pegInterferon", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute on Drug Abuse (NIDA)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 10, "start_date": "2003-06", "completion_date": "2006-06", "has_results": false, "last_update_posted_date": "2017-01-16", "last_synced_at": "2026-10-09T09:07:03.730Z", "location_count": 1, "location_summary": "Oakland, California", "locations": [ { "city": "Oakland", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00249574" }, { "nct_id": "NCT00135759", "title": "Addition of Naltrexone to Methadone Taper", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Heroin Dependence", "Opioid-Related Disorders", "Substance-Related Disorders" ], "interventions": [ { "name": "naltrexone", "type": "DRUG" }, { "name": "Placebo comparator", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute on Drug Abuse (NIDA)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 174, "start_date": "2005-04", "completion_date": "2006-07", "has_results": false, "last_update_posted_date": "2017-01-12", "last_synced_at": "2026-10-09T09:07:03.730Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00135759" }, { "nct_id": "NCT00637000", "title": "Induction of Opioid-Dependent Individuals Onto Buprenorphine and Buprenorphine/Naloxone", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Opioid-related Disorders" ], "interventions": [ { "name": "Buprenorphine soluble film", "type": "DRUG" }, { "name": "Buprenorphine/naloxone film strip", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Indivior Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 38, "start_date": "2008-03", "completion_date": "2008-09", "has_results": true, "last_update_posted_date": "2017-06-05", "last_synced_at": "2026-10-09T09:07:03.730Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00637000" }, { "nct_id": "NCT02194764", "title": "An Adherence Tool to Manage Narcotic -Addicted HIV Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Healthy Adults" ], "interventions": [ { "name": "Naltrexone and 2-butanol", "type": "DRUG" }, { "name": "2-butanol which is encapsulated (size 3 capsule) plus 50 mg of naltrexone (HCl form)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Xhale Assurance", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 8, "start_date": "2014-06", "completion_date": "2014-07", "has_results": false, "last_update_posted_date": "2014-07-18", "last_synced_at": "2026-10-09T09:07:03.730Z", "location_count": 1, "location_summary": "Gainesville, Florida", "locations": [ { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02194764" }, { "nct_id": "NCT04531176", "title": "EMI-EHP Weight Management and Type 2 Diabetes Pragmatic Trial", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Type 2 Diabetes", "Obesity" ], "interventions": [ { "name": "Weight Management Program (WMP)", "type": "OTHER" }, { "name": "Traditional care", "type": "OTHER" }, { "name": "Phentermine / Topiramate Extended Release Oral Capsule", "type": "DRUG" }, { "name": "naltrexone/bupropion extended-release", "type": "DRUG" }, { "name": "liraglutide 3.0 mg", "type": "DRUG" }, { "name": "Orlistat", "type": "DRUG" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "The Cleveland Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 74, "start_date": "2020-09-01", "completion_date": "2023-08-04", "has_results": true, "last_update_posted_date": "2024-09-19", "last_synced_at": "2026-10-09T09:07:03.730Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT04531176" }, { "nct_id": "NCT02330419", "title": "Better Than Study: Targeting Heavy Alcohol Use With Naltrexone Among Men Who Have Sex With Men (MSM)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Binge Drinking", "HIV" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Naltrexone", "type": "DRUG" }, { "name": "Medical Management (MM) counseling for alcohol use:", "type": "BEHAVIORAL" }, { "name": "Urinalysis for novel alcohol biochemical markers:", "type": "DIAGNOSTIC_TEST" }, { "name": "Behavioral survey measurements:", "type": "BEHAVIORAL" }, { "name": "Dried Blood Spot (DSB) Testing for Phosphatidylethanol", "type": "DIAGNOSTIC_TEST" }, { "name": "Ecological Momentary Assessment", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL", "DIAGNOSTIC_TEST" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "MALE", "summary": "18 Years to 70 Years · Male only" }, "enrollment_count": 120, "start_date": "2015-04", "completion_date": "2021-01", "has_results": true, "last_update_posted_date": "2025-04-20", "last_synced_at": "2026-10-09T09:07:03.730Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02330419" }, { "nct_id": "NCT04249882", "title": "A Novel Human Lab Model for Screening AUD Medications", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Alcohol Use Disorder" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "Naltrexone", "type": "DRUG" }, { "name": "Varenicline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 53, "start_date": "2020-01-28", "completion_date": "2022-06-28", "has_results": true, "last_update_posted_date": "2023-09-14", "last_synced_at": "2026-10-09T09:07:03.730Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04249882" }, { "nct_id": "NCT02885311", "title": "Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Alcohol-Related Disorders", "Alcohol Drinking", "Alcoholism", "Alcohol Abuse", "Alcohol Use Disorders" ], "interventions": [ { "name": "Motivation Enhancement Therapy", "type": "BEHAVIORAL" }, { "name": "Modified Behavioral Self-Control Therapy", "type": "BEHAVIORAL" }, { "name": "Naltrexone", "type": "DRUG" }, { "name": "Brief Advice", "type": "BEHAVIORAL" }, { "name": "Referral to specialty substance use disorder treatment", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "DRUG", "OTHER" ], "sponsor": "Northwell Health", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 27, "start_date": "2017-01", "completion_date": "2018-10", "has_results": true, "last_update_posted_date": "2023-10-30", "last_synced_at": "2026-10-09T09:07:03.730Z", "location_count": 1, "location_summary": "Great Neck, New York", "locations": [ { "city": "Great Neck", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02885311" }, { "nct_id": "NCT05644587", "title": "Novel Induction to Buprenorphine/Naloxone", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Opioid Use Disorder", "Opioid Use", "Opioid Abuse", "Opioid Misuse", "Opioid Dependence" ], "interventions": [ { "name": "buprenorphine/naloxone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bicycle Health", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 33, "start_date": "2023-02-06", "completion_date": "2023-11-30", "has_results": false, "last_update_posted_date": "2024-08-20", "last_synced_at": "2026-10-09T09:07:03.730Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05644587" }, { "nct_id": "NCT00105482", "title": "Targeted Interventions for Weight-Concerned Smokers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Nicotine Dependence" ], "interventions": [ { "name": "Naltrexone", "type": "DRUG" }, { "name": "Transdermal nicotine replacement", "type": "DRUG" }, { "name": "Behavioral counseling", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 172, "start_date": "2005-01", "completion_date": "2009-10", "has_results": true, "last_update_posted_date": "2013-03-05", "last_synced_at": "2026-10-09T09:07:03.730Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT00105482" } ] }