{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Naproxen+Sodium+ER+Placebo", "query": { "intervention": "Naproxen Sodium ER Placebo" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 6, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-28T07:45:13.819Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02528188", "title": "Long Term Safety and Efficacy Study of Tanezumab in Subjects With Osteoarthritis of the Hip or Knee", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Pain", "Osteoarthritis, Hip", "Osteoarthritis, Knee" ], "interventions": [ { "name": "NSAID", "type": "DRUG" }, { "name": "Tanezumab 2.5 mg", "type": "BIOLOGICAL" }, { "name": "Tanezumab 5 mg", "type": "BIOLOGICAL" } ], "intervention_types": [ "DRUG", "BIOLOGICAL" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 3021, "start_date": "2015-07-21", "completion_date": "2019-02-27", "has_results": true, "last_update_posted_date": "2020-01-10", "last_synced_at": "2026-09-28T07:45:13.819Z", "location_count": 299, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 187 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT02528188" }, { "nct_id": "NCT00720057", "title": "Assessing the Analgesic Efficacy of Naproxen Sodium in Postsurgical Dental Pain.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Toothache" ], "interventions": [ { "name": "Naproxen Sodium ER (BAYH6689)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bayer", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "16 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "16 Years to 45 Years" }, "enrollment_count": 312, "start_date": "2008-06", "completion_date": "2008-08", "has_results": true, "last_update_posted_date": "2015-08-25", "last_synced_at": "2026-09-28T07:45:13.819Z", "location_count": 3, "location_summary": "Austin, Texas • Salt Lake City, Utah", "locations": [ { "city": "Austin", "state": "Texas" }, { "city": "Austin", "state": "Texas" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT00720057" }, { "nct_id": "NCT00913627", "title": "Study Evaluating Ibuprofen 600 mg Extended Release (ER) For Dental Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pain" ], "interventions": [ { "name": "ibuprofen", "type": "DRUG" }, { "name": "naproxen", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "16 Years to 40 Years" }, "enrollment_count": 196, "start_date": "2009-05-07", "completion_date": "2009-08-05", "has_results": true, "last_update_posted_date": "2018-03-22", "last_synced_at": "2026-09-28T07:45:13.819Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT00913627" }, { "nct_id": "NCT01389284", "title": "Evaluate Efficacy and Safety of Extended Release (ER) Naproxen Sodium", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Pain, Postoperative" ], "interventions": [ { "name": "Naproxen Sodium ER (BAYH6689)", "type": "DRUG" }, { "name": "Naproxen Sodium IR (Aleve, BAYH6689)", "type": "DRUG" }, { "name": "Naproxen Sodium ER Placebo", "type": "DRUG" }, { "name": "Naproxen Sodium IR Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bayer", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "15 Years", "maximum_age": null, "sex": "ALL", "summary": "15 Years and older" }, "enrollment_count": 300, "start_date": "2011-06", "completion_date": "2011-09", "has_results": true, "last_update_posted_date": "2015-08-25", "last_synced_at": "2026-09-28T07:45:13.819Z", "location_count": 1, "location_summary": "Austin, Texas", "locations": [ { "city": "Austin", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01389284" }, { "nct_id": "NCT04285853", "title": "Are Opioids Needed After ACL Reconstruction", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Anterior Cruciate Ligament Rupture" ], "interventions": [ { "name": "Oxycodone", "type": "DRUG" }, { "name": "Placebo oral tablet", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "14 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "14 Years to 40 Years" }, "enrollment_count": 98, "start_date": "2020-09-16", "completion_date": "2022-09-19", "has_results": true, "last_update_posted_date": "2023-10-11", "last_synced_at": "2026-09-28T07:45:13.819Z", "location_count": 3, "location_summary": "Atlanta, Georgia • Tucker, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Tucker", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT04285853" }, { "nct_id": "NCT03570554", "title": "A Pilot Study Assessing the Treatment Responsiveness of a Novel Osteoarthritis Stiffness Scale", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Osteoarthritis, Knee" ], "interventions": [ { "name": "Naproxen Sodium (Aleve, BAY117031)", "type": "DRUG" }, { "name": "Acetaminophen ER", "type": "DRUG" }, { "name": "Celecoxib", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bayer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "40 Years to 80 Years" }, "enrollment_count": 41, "start_date": "2018-06-29", "completion_date": "2019-06-14", "has_results": true, "last_update_posted_date": "2020-06-19", "last_synced_at": "2026-09-28T07:45:13.819Z", "location_count": 5, "location_summary": "Chandler, Arizona • Pinellas Park, Florida • Chicago, Illinois + 2 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Pinellas Park", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Cincinnati", "state": "Ohio" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03570554" } ] }