{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nasal+saline+irrigation",
    "query": {
      "intervention": "Nasal saline irrigation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 45,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nasal+saline+irrigation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-29T05:28:47.519Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03014687",
      "title": "Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Antibiotics",
        "Pituitary Adenoma"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Oral Antibiotics cefdinir or trimethoprim/sulfamethoxazole",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Joseph's Hospital and Medical Center, Phoenix",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "18 Years to 84 Years"
      },
      "enrollment_count": 116,
      "start_date": "2017-07-01",
      "completion_date": "2019-07",
      "has_results": false,
      "last_update_posted_date": "2018-08-15",
      "last_synced_at": "2026-09-29T05:28:47.519Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03014687"
    },
    {
      "nct_id": "NCT04559035",
      "title": "Nasal Irrigation to Reduce COVID-19 Morbidity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Covid19"
      ],
      "interventions": [
        {
          "name": "Nasal lavage",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Augusta University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 239,
      "start_date": "2020-09-24",
      "completion_date": "2021-11-04",
      "has_results": false,
      "last_update_posted_date": "2021-12-28",
      "last_synced_at": "2026-09-29T05:28:47.519Z",
      "location_count": 1,
      "location_summary": "Augusta, Georgia",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04559035"
    },
    {
      "nct_id": "NCT06006884",
      "title": "A Study of Post COVID-19 Mechanisms for Chronic Lung Sequelae",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "COVID-19"
      ],
      "interventions": [
        {
          "name": "Bronchoscopies and Bronchoalveolar Lavages (BALs)",
          "type": "PROCEDURE"
        },
        {
          "name": "Chest Tomography (CT)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Electrocardiogram (ECG)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Pulmonary function tests (PFTs)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "6 minute walk test (6MWT)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 67,
      "start_date": "2024-01-10",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2026-05-07",
      "last_synced_at": "2026-09-29T05:28:47.519Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06006884"
    },
    {
      "nct_id": "NCT02413125",
      "title": "Comparison of Nasal Saline Irrigation Bottle Contamination Between Two Solutions",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sinusitis"
      ],
      "interventions": [
        {
          "name": "ChitoRhino irrigation solution",
          "type": "DEVICE"
        },
        {
          "name": "Normal saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2015-02",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2015-04-14",
      "last_synced_at": "2026-09-29T05:28:47.519Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02413125"
    },
    {
      "nct_id": "NCT05659524",
      "title": "Nasal Outcomes Using Saline Irrigations After Endonasal Pituitary Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pituitary Tumor"
      ],
      "interventions": [
        {
          "name": "Nasal saline irrigation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Lori Wood",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "19 Years to 85 Years"
      },
      "enrollment_count": 140,
      "start_date": "2020-12-18",
      "completion_date": "2029-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-04-19",
      "last_synced_at": "2026-09-29T05:28:47.519Z",
      "location_count": 2,
      "location_summary": "Phoenix, Arizona • Cleveland, Ohio",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05659524"
    },
    {
      "nct_id": "NCT01700725",
      "title": "Gulf War Illness Nasal Irrigation Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Persian Gulf Syndrome",
        "Chronic Sinusitis",
        "Fatigue",
        "Acute Sinusitis"
      ],
      "interventions": [
        {
          "name": "Nasal Irrigation - Saline",
          "type": "OTHER"
        },
        {
          "name": "Nasal Irrigation - Xylitol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "35 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2012-10",
      "completion_date": "2017-05",
      "has_results": true,
      "last_update_posted_date": "2019-05-21",
      "last_synced_at": "2026-09-29T05:28:47.519Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01700725"
    },
    {
      "nct_id": "NCT04964414",
      "title": "Treatment of Pediatric Patients That Lost Sense of Smell Due to COVID-19",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Dysosmia",
        "Anosmia",
        "Covid19"
      ],
      "interventions": [
        {
          "name": "Smell Retraining",
          "type": "OTHER"
        },
        {
          "name": "Budesonide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Amanda Stapleton",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "6 Years to 21 Years"
      },
      "enrollment_count": 20,
      "start_date": "2021-09-30",
      "completion_date": "2023-03-29",
      "has_results": true,
      "last_update_posted_date": "2024-06-13",
      "last_synced_at": "2026-09-29T05:28:47.519Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04964414"
    },
    {
      "nct_id": "NCT06996951",
      "title": "Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cystic Fibrosis (CF)",
        "Chronic Rhinosinusitis (CRS)"
      ],
      "interventions": [
        {
          "name": "STOP NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID",
          "type": "OTHER"
        },
        {
          "name": "CONTINUE NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 64,
      "start_date": "2025-07-02",
      "completion_date": "2026-07",
      "has_results": false,
      "last_update_posted_date": "2025-12-16",
      "last_synced_at": "2026-09-29T05:28:47.519Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06996951"
    },
    {
      "nct_id": "NCT03979209",
      "title": "Potential for Cortisol Suppression With the Use of High Volume Nasal Mometasone Irrigations in Varying Dosages.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Chronic Rhinosinusitis (Diagnosis)"
      ],
      "interventions": [
        {
          "name": "Nasal Mometasone Rinse",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 16,
      "start_date": "2019-01-14",
      "completion_date": "2022-07-28",
      "has_results": true,
      "last_update_posted_date": "2024-08-12",
      "last_synced_at": "2026-09-29T05:28:47.519Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03979209"
    },
    {
      "nct_id": "NCT04242368",
      "title": "Hypertonic Versus Isotonic Saline Irrigations for Chronic Rhinosinusitis",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Chronic Rhinosinusitis (Diagnosis)"
      ],
      "interventions": [
        {
          "name": "Isotonic saline",
          "type": "DRUG"
        },
        {
          "name": "Hypertonic Nasal Wash",
          "type": "DRUG"
        },
        {
          "name": "Fluticasone Propionate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2020-07-01",
      "completion_date": "2021-07-01",
      "has_results": false,
      "last_update_posted_date": "2021-03-18",
      "last_synced_at": "2026-09-29T05:28:47.519Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04242368"
    }
  ]
}