{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Near+Infrared+Spectroscopy+%28NIRS%29&page=2",
    "query": {
      "intervention": "Near Infrared Spectroscopy (NIRS)",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Near+Infrared+Spectroscopy+%28NIRS%29&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-29T23:36:20.927Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02990078",
      "title": "Non-invasive Measurement of Cerebrovascular Reactivity After Traumatic Brain Injury",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "TBI"
      ],
      "interventions": [
        {
          "name": "Sildenafil citrate",
          "type": "DRUG"
        },
        {
          "name": "Functional Near Infared Spectroscopy",
          "type": "DEVICE"
        },
        {
          "name": "Hypercapnia Challenge",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 26,
      "start_date": "2016-12",
      "completion_date": "2022-09-30",
      "has_results": false,
      "last_update_posted_date": "2022-10-13",
      "last_synced_at": "2026-09-29T23:36:20.927Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02990078"
    },
    {
      "nct_id": "NCT01352260",
      "title": "Near-Infrared Spectroscopy Comparison Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Total Aortic Arch Replacement"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Nonin Medical, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 17,
      "start_date": "2011-05",
      "completion_date": "2012-04",
      "has_results": false,
      "last_update_posted_date": "2012-05-21",
      "last_synced_at": "2026-09-29T23:36:20.927Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01352260"
    },
    {
      "nct_id": "NCT02147769",
      "title": "Cerebral Oxygenation and Autoregulation in Preterm Infants",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Intraventricular Hemorrhage of Prematurity",
        "Complications of Prematurity"
      ],
      "interventions": [
        {
          "name": "NIRS monitoring",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "Up to 24 Hours"
      },
      "enrollment_count": 111,
      "start_date": "2014-05",
      "completion_date": "2018-03",
      "has_results": true,
      "last_update_posted_date": "2020-04-07",
      "last_synced_at": "2026-09-29T23:36:20.927Z",
      "location_count": 7,
      "location_summary": "Birmingham, Alabama • Palo Alto, California • San Jose, California + 4 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Springfield",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02147769"
    },
    {
      "nct_id": "NCT01730079",
      "title": "Near Infrared Spectroscopy in Children With Autism and ADHD",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Attention Deficit Disorder With Hyperactivity",
        "Attention Deficit Disorder",
        "Attention Deficit Hyperactivity Disorder",
        "Autism",
        "Autism Spectrum Disorders"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "8 Years",
        "sex": "ALL",
        "summary": "4 Years to 8 Years"
      },
      "enrollment_count": 42,
      "start_date": "2012-10-23",
      "completion_date": "2017-04-11",
      "has_results": false,
      "last_update_posted_date": "2019-10-18",
      "last_synced_at": "2026-09-29T23:36:20.927Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01730079"
    },
    {
      "nct_id": "NCT01082536",
      "title": "Analysis of Cerebral Perfusion Using Head Ultrasound and Multisource Detector Near Infrared Spectroscopy (NIRS) Imaging",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Heart Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "2 Months",
        "sex": "ALL",
        "summary": "Up to 2 Months"
      },
      "enrollment_count": 0,
      "start_date": "2013-03-28",
      "completion_date": "2019-05",
      "has_results": false,
      "last_update_posted_date": "2019-01-31",
      "last_synced_at": "2026-09-29T23:36:20.927Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01082536"
    },
    {
      "nct_id": "NCT05052216",
      "title": "Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pediatric Obstructive Sleep Apnea"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "3 Years to 12 Years"
      },
      "enrollment_count": 120,
      "start_date": "2022-08-25",
      "completion_date": "2028-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-09-28",
      "last_synced_at": "2026-09-29T23:36:20.927Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05052216"
    },
    {
      "nct_id": "NCT07825363",
      "title": "Clinical Evaluation of NIRSense Tissue Oximetry Sensor Monitoring to Early Detect Cardiogenic Shock",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiogenic Shock",
        "Acute Myocardial Infarction",
        "Acute Decompensated Heart Failure"
      ],
      "interventions": [
        {
          "name": "NIRSense Tissue Oximetry Sensor System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "NIRSense Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2025-06-17",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2026-09-17",
      "last_synced_at": "2026-09-29T23:36:20.927Z",
      "location_count": 1,
      "location_summary": "Weston, Florida",
      "locations": [
        {
          "city": "Weston",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07825363"
    },
    {
      "nct_id": "NCT05996575",
      "title": "Investigating Mild Cognitive Impairment in Patients And Controls With TD-fNIRS",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "fNIRS measurement",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Kernel",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "55 Years to 85 Years"
      },
      "enrollment_count": 133,
      "start_date": "2023-07-25",
      "completion_date": "2024-06-13",
      "has_results": false,
      "last_update_posted_date": "2024-07-03",
      "last_synced_at": "2026-09-29T23:36:20.927Z",
      "location_count": 6,
      "location_summary": "Carlsbad, California • Costa Mesa, California • Escondido, California + 3 more",
      "locations": [
        {
          "city": "Carlsbad",
          "state": "California"
        },
        {
          "city": "Costa Mesa",
          "state": "California"
        },
        {
          "city": "Escondido",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Santa Ana",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05996575"
    },
    {
      "nct_id": "NCT05560867",
      "title": "Neural Mechanisms of Motor Recovery With Technology Assisted Training",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hemiparesis",
        "Stroke Sequelae"
      ],
      "interventions": [
        {
          "name": "robot-assisted training",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "88 Years",
        "sex": "ALL",
        "summary": "18 Years to 88 Years"
      },
      "enrollment_count": 4,
      "start_date": "2022-12-14",
      "completion_date": "2024-05-01",
      "has_results": false,
      "last_update_posted_date": "2024-08-26",
      "last_synced_at": "2026-09-29T23:36:20.927Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05560867"
    },
    {
      "nct_id": "NCT01768052",
      "title": "Functional Brain Imaging Study of Response to Repetitive TMS (rTMS) Treatment of Major Depression",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Major Depression"
      ],
      "interventions": [
        {
          "name": "functional Near Infrared Spectroscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mclean Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "21 Years to 45 Years"
      },
      "enrollment_count": 40,
      "start_date": "2013-06",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2015-05-04",
      "last_synced_at": "2026-09-29T23:36:20.927Z",
      "location_count": 2,
      "location_summary": "Belmont, Massachusetts",
      "locations": [
        {
          "city": "Belmont",
          "state": "Massachusetts"
        },
        {
          "city": "Belmont",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01768052"
    }
  ]
}