{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Near-Infrared+Spectroscopy+%28NIRS%29&page=6",
    "query": {
      "intervention": "Near-Infrared Spectroscopy (NIRS)",
      "page": 6
    },
    "page_size": 10
  },
  "pagination": {
    "page": 6,
    "page_size": 10,
    "total_count": 216,
    "total_pages": 22,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Near-Infrared+Spectroscopy+%28NIRS%29&page=7&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Near-Infrared+Spectroscopy+%28NIRS%29&page=5&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-09T16:42:03.960Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02793999",
      "title": "Perinatal Brain Injury: Potential of Innovative NIRS to Optimize Hypothermia",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hypoxic Ischemic Brain Injury",
        "Neonatal Encephalopathy"
      ],
      "interventions": [
        {
          "name": "Near-Infrared Spectroscopy (NIRS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "Up to 2 Years"
      },
      "enrollment_count": 125,
      "start_date": "2015-05",
      "completion_date": "2028-05",
      "has_results": false,
      "last_update_posted_date": "2025-12-10",
      "last_synced_at": "2026-10-09T16:42:03.960Z",
      "location_count": 3,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02793999"
    },
    {
      "nct_id": "NCT01289470",
      "title": "Clinical Assessment of Nonin 7600 Near Infrared Spectroscopy (NIRS) Tissue Oximetry During Cardiovascular Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart; Dysfunction Postoperative, Cardiac Surgery"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Nonin Medical, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2011-01",
      "completion_date": "2012-03",
      "has_results": false,
      "last_update_posted_date": "2012-05-21",
      "last_synced_at": "2026-10-09T16:42:03.960Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01289470"
    },
    {
      "nct_id": "NCT02149082",
      "title": "Near-infrared Spectroscopy (NIRS) for Intracranial Hematoma Detection in Children",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Intracranial Hematoma"
      ],
      "interventions": [
        {
          "name": "Infrascanner Model 2000",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 465,
      "start_date": "2014-06",
      "completion_date": "2018-09",
      "has_results": false,
      "last_update_posted_date": "2018-11-07",
      "last_synced_at": "2026-10-09T16:42:03.960Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02149082"
    },
    {
      "nct_id": "NCT05793827",
      "title": "Pilot Trial for Adults With Acquired Brain Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acquired Brain Injury",
        "Traumatic Brain Injury",
        "Stroke"
      ],
      "interventions": [
        {
          "name": "Adapted Hatha Yoga",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Low-Impact Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Colorado State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2023-01-30",
      "completion_date": "2023-11-17",
      "has_results": false,
      "last_update_posted_date": "2024-06-26",
      "last_synced_at": "2026-10-09T16:42:03.960Z",
      "location_count": 1,
      "location_summary": "Fort Collins, Colorado",
      "locations": [
        {
          "city": "Fort Collins",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05793827"
    },
    {
      "nct_id": "NCT07610746",
      "title": "Cerebral Physiology of NOWS",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neonatal Opioid Withdrawal",
        "Neonatal Opioid Withdrawal Syndrome",
        "Opioid Use Disorder",
        "Intrauterine Exposure"
      ],
      "interventions": [
        {
          "name": "FD-NIRS and DCS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Day",
        "sex": "ALL",
        "summary": "Up to 1 Day"
      },
      "enrollment_count": 46,
      "start_date": "2026-08-11",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2026-08-19",
      "last_synced_at": "2026-10-09T16:42:03.960Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07610746"
    },
    {
      "nct_id": "NCT02016599",
      "title": "Effects of Transitional Circulation in ELBW Infants",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neonatal Prematurity",
        "Hypotension"
      ],
      "interventions": [
        {
          "name": "Monitoring and biospecimen collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Week",
        "sex": "ALL",
        "summary": "Up to 1 Week"
      },
      "enrollment_count": 200,
      "start_date": "2017-09-22",
      "completion_date": "2032-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-10-09T16:42:03.960Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02016599"
    },
    {
      "nct_id": "NCT04639583",
      "title": "Use of NIRS in Preterm Population Born at Altitude",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prematurity; Extreme"
      ],
      "interventions": [
        {
          "name": "Near-infrared spectroscopy (NIRS) utilization",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of New Mexico",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Hours",
        "maximum_age": "24 Hours",
        "sex": "ALL",
        "summary": "0 Hours to 24 Hours"
      },
      "enrollment_count": 21,
      "start_date": "2021-10-01",
      "completion_date": "2023-06-30",
      "has_results": true,
      "last_update_posted_date": "2024-05-29",
      "last_synced_at": "2026-10-09T16:42:03.960Z",
      "location_count": 1,
      "location_summary": "Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04639583"
    },
    {
      "nct_id": "NCT07044596",
      "title": "Non-invasive Stimulation of the Glymphatic System for Slowing Cognitive Decline",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Traumatic Brain Injury",
        "Post Concussion Syndrome"
      ],
      "interventions": [
        {
          "name": "Functional near-infrared spectroscopy (fNIRS)",
          "type": "DEVICE"
        },
        {
          "name": "V1 stimulation electrodes",
          "type": "DEVICE"
        },
        {
          "name": "Magnetic Resonance Imaging (MRI)",
          "type": "DEVICE"
        },
        {
          "name": "MAGNUS scanner",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "20 Years to 85 Years"
      },
      "enrollment_count": 55,
      "start_date": "2025-11-13",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-10-09T16:42:03.960Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07044596"
    },
    {
      "nct_id": "NCT03650842",
      "title": "Changes in Cerebral Oxygenation During Laparoscopic Pyloromyotomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pyloric Stenosis"
      ],
      "interventions": [
        {
          "name": "Near infrared spectroscopy (NIRS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Nationwide Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 25,
      "start_date": "2017-07-07",
      "completion_date": "2018-10-08",
      "has_results": true,
      "last_update_posted_date": "2019-12-06",
      "last_synced_at": "2026-10-09T16:42:03.960Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03650842"
    },
    {
      "nct_id": "NCT06821568",
      "title": "Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease and Related Dementias",
        "Cognition",
        "Mobility Disability"
      ],
      "interventions": [
        {
          "name": "Personalized Transcranial Direct Current Stimulation (tDCS)",
          "type": "OTHER"
        },
        {
          "name": "Active-Sham",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Hebrew SeniorLife",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "65 Years to 90 Years"
      },
      "enrollment_count": 128,
      "start_date": "2025-09-02",
      "completion_date": "2029-06",
      "has_results": false,
      "last_update_posted_date": "2026-07-16",
      "last_synced_at": "2026-10-09T16:42:03.960Z",
      "location_count": 1,
      "location_summary": "Roslindale, Massachusetts",
      "locations": [
        {
          "city": "Roslindale",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06821568"
    }
  ]
}