{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Neoadjuvant+chemoradiotherapy", "query": { "intervention": "Neoadjuvant chemoradiotherapy" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 151, "total_pages": 16, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Neoadjuvant+chemoradiotherapy&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-22T20:23:33.829Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04418895", "title": "Neoadjuvant Therapy for Localized Rectal Adenocarcinoma", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Rectal Adenocarcinoma" ], "interventions": [ { "name": "Chemoradiation", "type": "OTHER" }, { "name": "short course radiation therapy", "type": "RADIATION" }, { "name": "mFOLFOX6", "type": "DRUG" }, { "name": "CAPOX", "type": "DRUG" }, { "name": "fluoropyrimidine +/- oxaliplatin", "type": "DRUG" } ], "intervention_types": [ "OTHER", "RADIATION", "DRUG" ], "sponsor": "UNC Lineberger Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 0, "start_date": "2021-08-13", "completion_date": "2025-05", "has_results": false, "last_update_posted_date": "2021-11-10", "last_synced_at": "2026-09-22T20:23:33.829Z", "location_count": 1, "location_summary": "Chapel Hill, North Carolina", "locations": [ { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT04418895" }, { "nct_id": "NCT00346164", "title": "Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Adult Alveolar Soft-part Sarcoma", "Adult Angiosarcoma", "Adult Epithelioid Sarcoma", "Adult Extraskeletal Chondrosarcoma", "Adult Extraskeletal Osteosarcoma", "Adult Fibrosarcoma", "Adult Leiomyosarcoma", "Adult Liposarcoma", "Adult Malignant Fibrous Histiocytoma", "Adult Malignant Hemangiopericytoma", "Adult Malignant Mesenchymoma", "Adult Neurofibrosarcoma", "Adult Synovial Sarcoma", "Childhood Alveolar Soft-part Sarcoma", "Childhood Angiosarcoma", "Childhood Epithelioid Sarcoma", "Childhood Fibrosarcoma", "Childhood Leiomyosarcoma", "Childhood Liposarcoma", "Childhood Malignant Mesenchymoma", "Childhood Neurofibrosarcoma", "Childhood Synovial Sarcoma", "Dermatofibrosarcoma Protuberans", "Metastatic Childhood Soft Tissue Sarcoma", "Nonmetastatic Childhood Soft Tissue Sarcoma", "Stage I Adult Soft Tissue Sarcoma", "Stage II Adult Soft Tissue Sarcoma", "Stage III Adult Soft Tissue Sarcoma", "Stage IV Adult Soft Tissue Sarcoma" ], "interventions": [ { "name": "doxorubicin hydrochloride", "type": "DRUG" }, { "name": "clinical observation", "type": "OTHER" }, { "name": "therapeutic conventional surgery", "type": "PROCEDURE" }, { "name": "3-dimensional conformal radiation therapy", "type": "RADIATION" }, { "name": "ifosfamide", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER", "PROCEDURE", "RADIATION" ], "sponsor": "Children's Oncology Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "29 Years", "sex": "ALL", "summary": "Up to 29 Years" }, "enrollment_count": 588, "start_date": "2007-02-05", "completion_date": "2022-03-31", "has_results": true, "last_update_posted_date": "2022-04-28", "last_synced_at": "2026-09-22T20:23:33.829Z", "location_count": 165, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 133 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Arcadia", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00346164" }, { "nct_id": "NCT04209790", "title": "Neoadjuvant Chemoradiation for Resectable Glioblastoma", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Glioblastoma", "Surgery", "High Grade Glioma" ], "interventions": [ { "name": "Neoadjuvant chemoradiation", "type": "RADIATION" }, { "name": "Drug Therapy with Temozolomide (benzolamide) (Standard of Care)", "type": "DRUG" }, { "name": "Surgery post Radiation and Temozolomide (benzolamide)", "type": "PROCEDURE" } ], "intervention_types": [ "RADIATION", "DRUG", "PROCEDURE" ], "sponsor": "Geisinger Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "89 Years", "sex": "ALL", "summary": "18 Years to 89 Years" }, "enrollment_count": 2, "start_date": "2020-04-01", "completion_date": "2022-09-14", "has_results": true, "last_update_posted_date": "2025-11-10", "last_synced_at": "2026-09-22T20:23:33.829Z", "location_count": 2, "location_summary": "Danville, Pennsylvania • Wilkes-Barre, Pennsylvania", "locations": [ { "city": "Danville", "state": "Pennsylvania" }, { "city": "Wilkes-Barre", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT04209790" }, { "nct_id": "NCT00707473", "title": "Docetaxel, Cisplatin and Fluorouracil in Treating Patients With Previously Untreated Stage II-IV Nasal Cavity and Paranasal Sinus Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Locally Advanced Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma", "Nasal Cavity and Paranasal Sinus Poorly Differentiated Carcinoma", "Sinonasal Undifferentiated Carcinoma", "Stage II Nasal Cavity and Paranasal Sinus Cancer AJCC v8", "Stage III Nasal Cavity and Paranasal Sinus Cancer AJCC v8", "Stage IVA Nasal Cavity and Paranasal Sinus Cancer AJCC v8", "Stage IVB Nasal Cavity and Paranasal Sinus Cancer AJCC v8" ], "interventions": [ { "name": "Carboplatin", "type": "DRUG" }, { "name": "Chemoradiotherapy", "type": "OTHER" }, { "name": "Cisplatin", "type": "DRUG" }, { "name": "Definitive Surgical Resection", "type": "PROCEDURE" }, { "name": "Docetaxel", "type": "DRUG" }, { "name": "Fluorouracil", "type": "DRUG" }, { "name": "Quality-of-Life Assessment", "type": "PROCEDURE" }, { "name": "Radiation Therapy", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "OTHER", "PROCEDURE", "RADIATION" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "17 Years", "maximum_age": null, "sex": "ALL", "summary": "17 Years and older" }, "enrollment_count": 31, "start_date": "2008-06-16", "completion_date": "2026-06-01", "has_results": true, "last_update_posted_date": "2026-07-17", "last_synced_at": "2026-09-22T20:23:33.829Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00707473" }, { "nct_id": "NCT07650266", "title": "A Study of Cemiplimab and Fianlimab in People With Nasopharyngeal Carcinoma", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Nasopharyngeal Carcinoma", "Nasopharyngeal Cancer", "Nasopharynx Carcinoma", "Nasopharynx Cancer" ], "interventions": [ { "name": "Cemiplimab", "type": "DRUG" }, { "name": "Fianlimab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2026-09", "completion_date": "2030-07", "has_results": false, "last_update_posted_date": "2026-08-11", "last_synced_at": "2026-09-22T20:23:33.829Z", "location_count": 7, "location_summary": "Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more", "locations": [ { "city": "Basking Ridge", "state": "New Jersey" }, { "city": "Middletown", "state": "New Jersey" }, { "city": "Montvale", "state": "New Jersey" }, { "city": "Commack", "state": "New York" }, { "city": "Harrison", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT07650266" }, { "nct_id": "NCT00727441", "title": "Vaccine Therapy With or Without Cyclophosphamide in Treating Patients Undergoing Chemotherapy and Radiation Therapy for Stage I or Stage II Pancreatic Cancer That Can Be Removed by Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pancreatic Cancer" ], "interventions": [ { "name": "GVAX pancreatic cancer vaccine", "type": "BIOLOGICAL" }, { "name": "cyclophosphamide", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "120 Years", "sex": "ALL", "summary": "18 Years to 120 Years" }, "enrollment_count": 87, "start_date": "2008-07-02", "completion_date": "2019-02", "has_results": true, "last_update_posted_date": "2020-02-25", "last_synced_at": "2026-09-22T20:23:33.829Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00727441" }, { "nct_id": "NCT00216086", "title": "Capecitabine + Irinotecan Followed by Combined Modality Capecitabine and Radiation in Locally Advanced Rectal Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Rectal Cancer" ], "interventions": [ { "name": "Capecitabine", "type": "DRUG" }, { "name": "Irinotecan", "type": "DRUG" }, { "name": "EUS", "type": "PROCEDURE" }, { "name": "Neoadjuvant Chemotherapy", "type": "DRUG" }, { "name": "Preoperative Radiation", "type": "PROCEDURE" }, { "name": "Surgery", "type": "PROCEDURE" }, { "name": "Adjuvant Chemotherapy", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Gabi Chiorean, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 22, "start_date": "2005-05", "completion_date": "2008-05", "has_results": true, "last_update_posted_date": "2016-06-06", "last_synced_at": "2026-09-22T20:23:33.829Z", "location_count": 9, "location_summary": "Elkhart, Indiana • Fort Wayne, Indiana • Goshen, Indiana + 5 more", "locations": [ { "city": "Elkhart", "state": "Indiana" }, { "city": "Fort Wayne", "state": "Indiana" }, { "city": "Goshen", "state": "Indiana" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT00216086" }, { "nct_id": "NCT00273546", "title": "Induction Chemotherapy Comparing Taxotere® Cisplatin and 5-Fluorouracil (TPF) With Standard Cisplatin and 5-Fluorouracil (PF) Followed by Chemoradiation in Locally Advanced Head and Neck Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Cancer" ], "interventions": [ { "name": "XRP6976 (Docetaxel/Taxotere)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sanofi", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 500, "start_date": "1999-05", "completion_date": "2006-02", "has_results": false, "last_update_posted_date": "2009-04-29", "last_synced_at": "2026-09-22T20:23:33.829Z", "location_count": 1, "location_summary": "Bridgewater, New Jersey", "locations": [ { "city": "Bridgewater", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT00273546" }, { "nct_id": "NCT02145390", "title": "Chemoradiation for Bladder Preservation After Complete Response to Neoadjuvant Chemotherapy", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Bladder Cancer", "Bladder Carcinoma", "Transition Cell Cancer", "Muscle Invasive Bladder Carcinoma" ], "interventions": [ { "name": "Transurethral Resection of the Bladder Tumor & Cystoscopy", "type": "PROCEDURE" }, { "name": "Intensity Modulated Radiation Therapy", "type": "RADIATION" }, { "name": "Expanded Prostate Cancer Index Composite Short Form 12", "type": "BEHAVIORAL" }, { "name": "International Prostate Symptom Score", "type": "BEHAVIORAL" } ], "intervention_types": [ "PROCEDURE", "RADIATION", "BEHAVIORAL" ], "sponsor": "University of Miami", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1, "start_date": "2016-01-05", "completion_date": "2017-04-25", "has_results": true, "last_update_posted_date": "2018-08-28", "last_synced_at": "2026-09-22T20:23:33.829Z", "location_count": 1, "location_summary": "Miami, Florida", "locations": [ { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02145390" }, { "nct_id": "NCT01613469", "title": "Maintenance Chemotherapy After Neoadjuvant Chemoradiation Therapy for Distal Rectal Cancer", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Rectal Neoplasms" ], "interventions": [ { "name": "5FU/Leucovorin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Marks, John, M.D.", "sponsor_class": "INDIV", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 5, "start_date": "2011-08", "completion_date": "2017-03-16", "has_results": false, "last_update_posted_date": "2018-08-16", "last_synced_at": "2026-09-22T20:23:33.829Z", "location_count": 1, "location_summary": "Wynnewood, Pennsylvania", "locations": [ { "city": "Wynnewood", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01613469" } ] }