{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Netupitant%2FPalonosetron", "query": { "intervention": "Netupitant/Palonosetron" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 9, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-04T00:59:12.914Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03040726", "title": "Netupitant and Palonosetron Hydrochloride in Preventing Chronic Nausea and Vomiting in Patients With Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Malignant Neoplasm", "Nausea", "Vomiting" ], "interventions": [ { "name": "Netupitant", "type": "DRUG" }, { "name": "Palonosetron", "type": "DRUG" }, { "name": "Palonosetron Hydrochloride", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" }, { "name": "Questionnaire Administration", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 53, "start_date": "2017-05-03", "completion_date": "2022-02-14", "has_results": true, "last_update_posted_date": "2023-10-17", "last_synced_at": "2026-09-04T00:59:12.914Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03040726" }, { "nct_id": "NCT06065722", "title": "Prevention of Breakthrough CINV in Patients Receiving Moderately or Highly Emetogenic Chemotherapy", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chemotherapy Induced Nausea and Vomiting" ], "interventions": [ { "name": "Akynzeo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Simon Williamson Clinic", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2023-09-09", "completion_date": "2023-12-31", "has_results": false, "last_update_posted_date": "2023-10-10", "last_synced_at": "2026-09-04T00:59:12.914Z", "location_count": 1, "location_summary": "Mount Olive, Alabama", "locations": [ { "city": "Mount Olive", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT06065722" }, { "nct_id": "NCT03403712", "title": "A Study to Assess the Safety and the Efficacy of IV Fosnetupitant/Palonosetron (260 mg/0.25 mg) Combination Compared to Oral Netupitant/Palonosetron (300 mg/0.5 mg) Combination for the Prevention of CINV in AC Chemotherapy in Women With Breast Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chemotherapy-induced Nausea and Vomiting" ], "interventions": [ { "name": "fosnetupitant/ palonosetron", "type": "DRUG" }, { "name": "netupitant/palonosetron", "type": "DRUG" }, { "name": "dexamethasone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Helsinn Healthcare SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 404, "start_date": "2018-03-16", "completion_date": "2018-09-19", "has_results": true, "last_update_posted_date": "2020-06-01", "last_synced_at": "2026-09-04T00:59:12.914Z", "location_count": 36, "location_summary": "Tucson, Arizona • Little Rock, Arkansas • Anaheim, California + 32 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" }, { "city": "Bakersfield", "state": "California" }, { "city": "Corona", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03403712" }, { "nct_id": "NCT02517021", "title": "A Safety Study of Intravenous Pro-Netupitant and Palonosetron Combination for the Prevention of Nausea and Vomiting", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chemotherapy-Induced Nausea and Vomiting" ], "interventions": [ { "name": "Pro-netupitant/Palonosetron", "type": "DRUG" }, { "name": "Netupitant/Palonosetron", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Helsinn Healthcare SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 405, "start_date": "2015-11", "completion_date": "2016-08", "has_results": true, "last_update_posted_date": "2018-06-20", "last_synced_at": "2026-09-04T00:59:12.914Z", "location_count": 11, "location_summary": "Santa Monica, California • Whittier, California • Grand Junction, Colorado + 8 more", "locations": [ { "city": "Santa Monica", "state": "California" }, { "city": "Whittier", "state": "California" }, { "city": "Grand Junction", "state": "Colorado" }, { "city": "Miami", "state": "Florida" }, { "city": "Peoria", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02517021" }, { "nct_id": "NCT01376297", "title": "A Safety Study of Oral Netupitant and Palonosetron for the Prevention of Nausea and Vomiting", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chemotherapy-Induced Nausea and Vomiting" ], "interventions": [ { "name": "Netupitant and Palonosetron", "type": "DRUG" }, { "name": "Aprepitant", "type": "DRUG" }, { "name": "Palonosetron", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Helsinn Healthcare SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 413, "start_date": "2011-07", "completion_date": null, "has_results": true, "last_update_posted_date": "2014-11-17", "last_synced_at": "2026-09-04T00:59:12.914Z", "location_count": 11, "location_summary": "Muscle Shoals, Alabama • Burbank, California • Los Angeles, California + 8 more", "locations": [ { "city": "Muscle Shoals", "state": "Alabama" }, { "city": "Burbank", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "East Orange", "state": "New Jersey" }, { "city": "Nyack", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01376297" }, { "nct_id": "NCT03367572", "title": "Treatment of Refractory Nausea and Vomiting in Patients With Breast Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Breast Carcinoma" ], "interventions": [ { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Netupitant/Palonosetron Hydrochloride", "type": "DRUG" }, { "name": "Olanzapine", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" }, { "name": "Prochlorperazine", "type": "DRUG" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Rochester NCORP Research Base", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 1363, "start_date": "2018-04-19", "completion_date": "2024-04-13", "has_results": true, "last_update_posted_date": "2025-09-25", "last_synced_at": "2026-09-04T00:59:12.914Z", "location_count": 18, "location_summary": "Honolulu, Hawaii • Decatur, Illinois • New Orleans, Louisiana + 15 more", "locations": [ { "city": "Honolulu", "state": "Hawaii" }, { "city": "Decatur", "state": "Illinois" }, { "city": "New Orleans", "state": "Louisiana" }, { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Grand Rapids", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT03367572" }, { "nct_id": "NCT01339260", "title": "An Efficacy and Safety Study of Oral Netupitant and Palonosetron for the Prevention of Nausea and Vomiting", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chemotherapy-Induced Nausea and Vomiting" ], "interventions": [ { "name": "Netupitant and Palonosetron", "type": "DRUG" }, { "name": "Palonosetron", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Helsinn Healthcare SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1455, "start_date": "2011-04", "completion_date": null, "has_results": true, "last_update_posted_date": "2014-11-26", "last_synced_at": "2026-09-04T00:59:12.914Z", "location_count": 28, "location_summary": "Anniston, Alabama • Muscle Shoals, Alabama • Hot Springs, Arkansas + 24 more", "locations": [ { "city": "Anniston", "state": "Alabama" }, { "city": "Muscle Shoals", "state": "Alabama" }, { "city": "Hot Springs", "state": "Arkansas" }, { "city": "Corona", "state": "California" }, { "city": "Fountain Valley", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01339260" }, { "nct_id": "NCT03097588", "title": "Netupitant and Palonosetron Hydrochloride in Preventing Chemotherapy Induced Nausea and Vomiting in Patients With Cancer Undergoing BEAM Conditioning Regimen Before Stem Cell Transplant", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Malignant Neoplasm" ], "interventions": [ { "name": "Netupitant", "type": "DRUG" }, { "name": "Palonosetron Hydrochloride", "type": "DRUG" }, { "name": "Questionnaire Administration", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "OHSU Knight Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 43, "start_date": "2017-04-27", "completion_date": "2020-03-20", "has_results": true, "last_update_posted_date": "2021-07-12", "last_synced_at": "2026-09-04T00:59:12.914Z", "location_count": 1, "location_summary": "Portland, Oregon", "locations": [ { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT03097588" }, { "nct_id": "NCT03204279", "title": "PK/PD Study of Netupitant and Palonosetron in Pediatric Patients for Prevention of Chemotherapy-induced Nausea and Vomiting", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chemotherapy-induced Nausea and Vomiting (CINV)" ], "interventions": [ { "name": "Netupitant", "type": "DRUG" }, { "name": "Palonosetron", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Helsinn Healthcare SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "17 Years", "sex": "ALL", "summary": "Up to 17 Years" }, "enrollment_count": 67, "start_date": "2017-08-31", "completion_date": "2019-09-30", "has_results": true, "last_update_posted_date": "2024-06-25", "last_synced_at": "2026-09-04T00:59:12.914Z", "location_count": 5, "location_summary": "Wilmington, Delaware • Jacksonville, Florida • Orlando, Florida + 2 more", "locations": [ { "city": "Wilmington", "state": "Delaware" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Orlando", "state": "Florida" }, { "city": "Scarborough", "state": "Maine" }, { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03204279" } ] }