{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+%2810+mg%29&page=2",
    "query": {
      "intervention": "Nicotine (10 mg)",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 106,
    "total_pages": 11,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+%2810+mg%29&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+%2810+mg%29&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-03T18:11:10.119Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04234997",
      "title": "Suvorexant to Reduce Symptoms of Nicotine Use",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Suvorexant 20 mg",
          "type": "DRUG"
        },
        {
          "name": "Suvorexant 0mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 14,
      "start_date": "2021-08-23",
      "completion_date": "2024-08-22",
      "has_results": true,
      "last_update_posted_date": "2025-10-01",
      "last_synced_at": "2026-10-03T18:11:10.119Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04234997"
    },
    {
      "nct_id": "NCT04488744",
      "title": "Smoking by IV Pulsed Nicotine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Nicotine 0.2mcg/kg/s and 1.0mcg/kg/s",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 13,
      "start_date": "2019-11-15",
      "completion_date": "2021-05-31",
      "has_results": false,
      "last_update_posted_date": "2021-07-20",
      "last_synced_at": "2026-10-03T18:11:10.119Z",
      "location_count": 1,
      "location_summary": "West Haven, Connecticut",
      "locations": [
        {
          "city": "West Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04488744"
    },
    {
      "nct_id": "NCT00756275",
      "title": "Varenicline and Motivational Advice for Smokers With Substance Use Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Nicotine Replacement Treatment (NRT)",
          "type": "DRUG"
        },
        {
          "name": "varenicline",
          "type": "DRUG"
        },
        {
          "name": "Behavioral counseling for smoking cessation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 158,
      "start_date": "2009-01",
      "completion_date": "2014-09",
      "has_results": true,
      "last_update_posted_date": "2018-08-27",
      "last_synced_at": "2026-10-03T18:11:10.119Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00756275"
    },
    {
      "nct_id": "NCT01259466",
      "title": "Internet-Administered Smoking Cessation Treatment for Overweight and Obese Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation",
        "Overweight",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Nicotine patch",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 54,
      "start_date": "2010-07",
      "completion_date": "2013-11",
      "has_results": true,
      "last_update_posted_date": "2015-09-28",
      "last_synced_at": "2026-10-03T18:11:10.119Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01259466"
    },
    {
      "nct_id": "NCT03176784",
      "title": "UW Quitting Using Intensive Treatment Study (QUITS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Tobacco Dependence"
      ],
      "interventions": [
        {
          "name": "Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "Placebo Patch",
          "type": "OTHER"
        },
        {
          "name": "Placebo Pill",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1251,
      "start_date": "2017-11-11",
      "completion_date": "2020-07-09",
      "has_results": true,
      "last_update_posted_date": "2023-01-23",
      "last_synced_at": "2026-10-03T18:11:10.119Z",
      "location_count": 2,
      "location_summary": "Madison, Wisconsin • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03176784"
    },
    {
      "nct_id": "NCT01341938",
      "title": "Nicotine Lozenges and Assisted Self-help for Smokeless Tobacco Cessation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smokeless Tobacco Cessation"
      ],
      "interventions": [
        {
          "name": "Commit® nicotine lozenges (4 mg) & self-help materials",
          "type": "DRUG"
        },
        {
          "name": "Commit® nicotine lozenges (4 mg) & phone counseling & self-help materials",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Phone counseling & self-help materials",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Oregon Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1067,
      "start_date": "2011-07",
      "completion_date": "2012-11",
      "has_results": false,
      "last_update_posted_date": "2021-08-04",
      "last_synced_at": "2026-10-03T18:11:10.119Z",
      "location_count": 1,
      "location_summary": "Eugene, Oregon",
      "locations": [
        {
          "city": "Eugene",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01341938"
    },
    {
      "nct_id": "NCT00032084",
      "title": "S0002 - A Program to Quit Smoking With or Without Bupropion in Treating Patients With Stage I or II Non-Small Cell Lung Cancer Who Have Undergone Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Lung Cancer"
      ],
      "interventions": [
        {
          "name": "smoking cessation intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "bupropion hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "nicotine",
          "type": "DRUG"
        },
        {
          "name": "psychosocial assessment and care",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "SWOG Cancer Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2002-01",
      "completion_date": "2004-02",
      "has_results": false,
      "last_update_posted_date": "2013-03-11",
      "last_synced_at": "2026-10-03T18:11:10.119Z",
      "location_count": 175,
      "location_summary": "Anniston, Alabama • Mobile, Alabama • Phoenix, Arizona + 115 more",
      "locations": [
        {
          "city": "Anniston",
          "state": "Alabama"
        },
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00032084"
    },
    {
      "nct_id": "NCT05184920",
      "title": "CSD201004: An Actual Use Study of P10 and P13 Nicotine Pouches Among U.S. Adult Smokers",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Smoking",
        "Tobacco Use",
        "Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "P1012919 nicotine pouch",
          "type": "OTHER"
        },
        {
          "name": "P1012915 nicotine pouch",
          "type": "OTHER"
        },
        {
          "name": "P1012914 nicotine pouch",
          "type": "OTHER"
        },
        {
          "name": "P1013315 nicotine pouch",
          "type": "OTHER"
        },
        {
          "name": "P1013119 nicotine pouch",
          "type": "OTHER"
        },
        {
          "name": "P1013218 nicotine pouch",
          "type": "OTHER"
        },
        {
          "name": "P1012818 nicotine pouch",
          "type": "OTHER"
        },
        {
          "name": "P1312915 nicotine pouch",
          "type": "OTHER"
        },
        {
          "name": "P1312914 nicotine pouch",
          "type": "OTHER"
        },
        {
          "name": "P1313015 nicotine pouch",
          "type": "OTHER"
        },
        {
          "name": "P1313314 nicotine pouch",
          "type": "OTHER"
        },
        {
          "name": "P1312815 nicotine pouch",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "RAI Services Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 1105,
      "start_date": "2022-01-19",
      "completion_date": "2022-04-29",
      "has_results": false,
      "last_update_posted_date": "2022-06-27",
      "last_synced_at": "2026-10-03T18:11:10.119Z",
      "location_count": 10,
      "location_summary": "Phoenix, Arizona • Atlanta, Georgia • Chicago, Illinois + 7 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05184920"
    },
    {
      "nct_id": "NCT05081154",
      "title": "CSD201002: Study to Assess Nicotine Uptake From P10 Nicotine Pouches",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "Product A",
          "type": "OTHER"
        },
        {
          "name": "Product B",
          "type": "OTHER"
        },
        {
          "name": "Product C",
          "type": "OTHER"
        },
        {
          "name": "Product D",
          "type": "OTHER"
        },
        {
          "name": "Product E",
          "type": "OTHER"
        },
        {
          "name": "Product F",
          "type": "OTHER"
        },
        {
          "name": "Product G",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "RAI Services Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 36,
      "start_date": "2021-10-20",
      "completion_date": "2021-11-24",
      "has_results": false,
      "last_update_posted_date": "2022-06-27",
      "last_synced_at": "2026-10-03T18:11:10.119Z",
      "location_count": 1,
      "location_summary": "Knoxville, Tennessee",
      "locations": [
        {
          "city": "Knoxville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05081154"
    },
    {
      "nct_id": "NCT02069392",
      "title": "Nicotinic Enhancement of Cognitive Remediation Training in Schizophrenia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Schizophrenia",
        "Schizoaffective Disorder"
      ],
      "interventions": [
        {
          "name": "Cognitive remediation training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine polacrilex lozenge",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 31,
      "start_date": "2015-01",
      "completion_date": "2017-06",
      "has_results": true,
      "last_update_posted_date": "2019-09-12",
      "last_synced_at": "2026-10-03T18:11:10.119Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02069392"
    }
  ]
}