{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+%2810+mg%29&page=5", "query": { "intervention": "Nicotine (10 mg)", "page": 5 }, "page_size": 10 }, "pagination": { "page": 5, "page_size": 10, "total_count": 106, "total_pages": 11, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+%2810+mg%29&page=6&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+%2810+mg%29&page=4&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-07T18:36:12.390Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04188873", "title": "Cessation Screening Project", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Nicotine Dependence" ], "interventions": [ { "name": "Preparation Varenicline and Standard Duration Varenicline", "type": "DRUG" }, { "name": "Preparation Varenicline and Extended Duration Varenicline", "type": "DRUG" }, { "name": "Standard Duration Varenicline", "type": "DRUG" }, { "name": "Extended Duration Varenicline", "type": "DRUG" }, { "name": "Preparation Combination NRT and Standard Duration Combination NRT", "type": "DRUG" }, { "name": "Preparation Combination NRT and Extended Duration Combination NRT", "type": "DRUG" }, { "name": "Standard Duration Combination NRT", "type": "DRUG" }, { "name": "Extended Duration Combination NRT", "type": "DRUG" }, { "name": "Intensive Counseling", "type": "BEHAVIORAL" }, { "name": "Minimal Counseling", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "University of Wisconsin, Madison", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 538, "start_date": "2020-12-10", "completion_date": "2025-05-08", "has_results": true, "last_update_posted_date": "2026-06-17", "last_synced_at": "2026-10-07T18:36:12.390Z", "location_count": 2, "location_summary": "Madison, Wisconsin • Milwaukee, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" }, { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT04188873" }, { "nct_id": "NCT07809854", "title": "Evaluating an Innovative Tobacco Treatment Approach for Veterans in Substance Use Treatment", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Cigarette Smoking", "Veterans" ], "interventions": [ { "name": "Healthy Changes Nicotine Replacement Therapy (NRT)", "type": "DRUG" }, { "name": "Cessation Treatment Nicotine Replacement Therapy (NRT)", "type": "DRUG" }, { "name": "Cessation Treatment Counseling", "type": "BEHAVIORAL" }, { "name": "Healthy Changes Counseling", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 112, "start_date": "2027-04-01", "completion_date": "2031-09-30", "has_results": false, "last_update_posted_date": "2026-09-14", "last_synced_at": "2026-10-07T18:36:12.390Z", "location_count": 1, "location_summary": "Madison, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT07809854" }, { "nct_id": "NCT01156610", "title": "Tobacco Treatment Outreach to Reduce Disparities for Primary Care Populations", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Smoking", "Smoking Cessation" ], "interventions": [ { "name": "Tobacco Treatment", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 706, "start_date": "2011-11", "completion_date": "2014-03", "has_results": false, "last_update_posted_date": "2014-03-06", "last_synced_at": "2026-10-07T18:36:12.390Z", "location_count": 2, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01156610" }, { "nct_id": "NCT02162849", "title": "Reward Sensitivity and Pharmacotherapy for Smoking Cessation", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Tobacco Use Cessation" ], "interventions": [ { "name": "Varenicline", "type": "DRUG" }, { "name": "Nicotine Patch", "type": "DRUG" }, { "name": "Placebo Patch", "type": "DRUG" }, { "name": "Placebo Tablet", "type": "DRUG" }, { "name": "Questionnaires", "type": "BEHAVIORAL" }, { "name": "Counseling Sessions", "type": "BEHAVIORAL" }, { "name": "Lab Session", "type": "OTHER" }, { "name": "Saliva Test", "type": "OTHER" } ], "intervention_types": [ "DRUG", "BEHAVIORAL", "OTHER" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 204, "start_date": "2015-12-14", "completion_date": "2028-02-28", "has_results": false, "last_update_posted_date": "2026-07-16", "last_synced_at": "2026-10-07T18:36:12.390Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02162849" }, { "nct_id": "NCT01926626", "title": "Evaluation of Moclobemide, a Reversible MAO-A Inhibitor, as an Adjunct to Nicotine Replacement Therapy in Female Smokers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Nicotine Dependence" ], "interventions": [ { "name": "Nicotine Patch", "type": "DRUG" }, { "name": "Moclobemide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Jed E. Rose", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "FEMALE", "summary": "18 Years to 65 Years · Female only" }, "enrollment_count": 76, "start_date": "2013-09", "completion_date": "2014-10", "has_results": true, "last_update_posted_date": "2017-08-23", "last_synced_at": "2026-10-07T18:36:12.390Z", "location_count": 3, "location_summary": "Charlotte, North Carolina • Durham, North Carolina • Winston-Salem, North Carolina", "locations": [ { "city": "Charlotte", "state": "North Carolina" }, { "city": "Durham", "state": "North Carolina" }, { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01926626" }, { "nct_id": "NCT00108342", "title": "Nicotine Delivery Systems: Research & Treatment", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Smoking" ], "interventions": [ { "name": "Nicotine gum - 2 mg and 4 mg", "type": "DRUG" }, { "name": "Nicotine lozenges - 2 mg and 4 mg", "type": "DRUG" }, { "name": "Nicotine inhaler (4 mg yield) - low and high \"dosage\" by frequency of puffing", "type": "DRUG" }, { "name": "Computer learning", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "US Department of Veterans Affairs", "sponsor_class": "FED", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 25, "start_date": "2007-10", "completion_date": "2009-12", "has_results": true, "last_update_posted_date": "2014-06-04", "last_synced_at": "2026-10-07T18:36:12.390Z", "location_count": 1, "location_summary": "West Los Angeles, California", "locations": [ { "city": "West Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00108342" }, { "nct_id": "NCT00690170", "title": "Nicotinic Modulation of Schizophrenia-like Information Processing Deficits in Healthy Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy Subjects" ], "interventions": [ { "name": "Ketamine", "type": "DRUG" }, { "name": "Nicotine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Ketamine and Nicotine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 30, "start_date": "2002-12", "completion_date": "2009-09", "has_results": false, "last_update_posted_date": "2012-05-09", "last_synced_at": "2026-10-07T18:36:12.390Z", "location_count": 1, "location_summary": "West Haven, Connecticut", "locations": [ { "city": "West Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT00690170" }, { "nct_id": "NCT00755716", "title": "Topiramate Alone and in Combination With the Nicotine Patch for Smoking Cessation: A Pilot Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Tobacco Dependence" ], "interventions": [ { "name": "Placebo (sugar pill)", "type": "DRUG" }, { "name": "Topiramate", "type": "DRUG" }, { "name": "Nicotine patch", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "UConn Health", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 57, "start_date": "2006-04", "completion_date": "2013-08", "has_results": true, "last_update_posted_date": "2017-08-16", "last_synced_at": "2026-10-07T18:36:12.390Z", "location_count": 1, "location_summary": "Farmington, Connecticut", "locations": [ { "city": "Farmington", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT00755716" }, { "nct_id": "NCT01120704", "title": "Evaluation of Treatments to Improve Smoking Cessation Medication Adherence", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Smoking", "Smoking Cessation", "Adherence", "Nicotine Dependence", "Motivation" ], "interventions": [ { "name": "Short Term Combination Nicotine Replacement Therapy (patch + gum)", "type": "DRUG" }, { "name": "Long Term Combination Nicotine Replacement Therapy (patch + gum)", "type": "DRUG" }, { "name": "Intensive Maintenance Counseling", "type": "BEHAVIORAL" }, { "name": "Cognitive Medication Adherence Counseling (CAM)", "type": "BEHAVIORAL" }, { "name": "Electronic Medication Monitoring Device (the Helping Hand) + Feedback", "type": "BEHAVIORAL" }, { "name": "Automated Adherence Prompting Phone Calls", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "University of Wisconsin, Madison", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 544, "start_date": "2010-06", "completion_date": "2014-05", "has_results": true, "last_update_posted_date": "2015-12-11", "last_synced_at": "2026-10-07T18:36:12.390Z", "location_count": 1, "location_summary": "Madison, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT01120704" }, { "nct_id": "NCT00710034", "title": "Efficacy of Oral Tobacco Products Compared to a Medicinal Nicotine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Tobacco Use Disorder" ], "interventions": [ { "name": "Oral tobacco", "type": "OTHER" }, { "name": "Nicotine Gum", "type": "DRUG" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 391, "start_date": "2010-04", "completion_date": "2014-05", "has_results": true, "last_update_posted_date": "2017-12-06", "last_synced_at": "2026-10-07T18:36:12.390Z", "location_count": 2, "location_summary": "Minneapolis, Minnesota • Eugene, Oregon", "locations": [ { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Eugene", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT00710034" } ] }