{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+%285+mg%29&page=3",
    "query": {
      "intervention": "Nicotine (5 mg)",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 115,
    "total_pages": 12,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+%285+mg%29&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+%285+mg%29&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-05T11:59:21.272Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00793468",
      "title": "Relapse Prevention Study in Newly Abstinent Smokers",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Substance Dependence"
      ],
      "interventions": [
        {
          "name": "GSK598809",
          "type": "DRUG"
        },
        {
          "name": "Nicotine Replacement Transdermal Patch",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2008-12",
      "completion_date": "2008-12",
      "has_results": false,
      "last_update_posted_date": "2016-02-15",
      "last_synced_at": "2026-10-05T11:59:21.272Z",
      "location_count": 10,
      "location_summary": "DeLand, Florida • Pembroke Pines, Florida • Stockbridge, Georgia + 7 more",
      "locations": [
        {
          "city": "DeLand",
          "state": "Florida"
        },
        {
          "city": "Pembroke Pines",
          "state": "Florida"
        },
        {
          "city": "Stockbridge",
          "state": "Georgia"
        },
        {
          "city": "Overland Park",
          "state": "Kansas"
        },
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00793468"
    },
    {
      "nct_id": "NCT00384696",
      "title": "Risk Perception Among Quitting Smokers",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Smoking"
      ],
      "interventions": [
        {
          "name": "Nicotine Replacement Therapy",
          "type": "DRUG"
        },
        {
          "name": "Questionnaire",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 220,
      "start_date": "2006-02-10",
      "completion_date": "2020-12-31",
      "has_results": false,
      "last_update_posted_date": "2019-05-24",
      "last_synced_at": "2026-10-05T11:59:21.272Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00384696"
    },
    {
      "nct_id": "NCT01120704",
      "title": "Evaluation of Treatments to Improve Smoking Cessation Medication Adherence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking",
        "Smoking Cessation",
        "Adherence",
        "Nicotine Dependence",
        "Motivation"
      ],
      "interventions": [
        {
          "name": "Short Term Combination Nicotine Replacement Therapy (patch + gum)",
          "type": "DRUG"
        },
        {
          "name": "Long Term Combination Nicotine Replacement Therapy (patch + gum)",
          "type": "DRUG"
        },
        {
          "name": "Intensive Maintenance Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Medication Adherence Counseling (CAM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Electronic Medication Monitoring Device (the Helping Hand) + Feedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Automated Adherence Prompting Phone Calls",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 544,
      "start_date": "2010-06",
      "completion_date": "2014-05",
      "has_results": true,
      "last_update_posted_date": "2015-12-11",
      "last_synced_at": "2026-10-05T11:59:21.272Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01120704"
    },
    {
      "nct_id": "NCT02564315",
      "title": "The Long-Term Quitting (Smoking Cessation) Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Nicotine Mini-Lozenge for 11 Months",
          "type": "DRUG"
        },
        {
          "name": "Preparation Phase Behavioral Reduction Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Preparation Phase Recycling Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Preparation Phase Control Treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation Phase Supportive Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation Phase Skill Training Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation Phase Brief Information",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation Phase Nicotine Patch + Nicotine Mini-Lozenge",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1154,
      "start_date": "2015-10-30",
      "completion_date": "2019-11-05",
      "has_results": false,
      "last_update_posted_date": "2020-02-17",
      "last_synced_at": "2026-10-05T11:59:21.272Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02564315"
    },
    {
      "nct_id": "NCT03674970",
      "title": "Effects of Random Nicotine Delivery on Smoking Cessation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Smoking Cessation",
        "Cigarette Smoking",
        "Smoking (Tobacco) Addiction"
      ],
      "interventions": [
        {
          "name": "Nicotine Film",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 45,
      "start_date": "2019-03-12",
      "completion_date": "2019-11-25",
      "has_results": true,
      "last_update_posted_date": "2021-01-22",
      "last_synced_at": "2026-10-05T11:59:21.272Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03674970"
    },
    {
      "nct_id": "NCT00087880",
      "title": "Maintaining Abstinence in Chronic Cigarette Smokers - 1",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Tobacco Use Disorder"
      ],
      "interventions": [
        {
          "name": "Bupropion and NRT",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute on Drug Abuse (NIDA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 407,
      "start_date": "2002-12",
      "completion_date": "2009-09",
      "has_results": false,
      "last_update_posted_date": "2017-01-12",
      "last_synced_at": "2026-10-05T11:59:21.272Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00087880"
    },
    {
      "nct_id": "NCT04755413",
      "title": "The Precision CAD Trial",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "Medical/Behavioral therapy",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care",
          "type": "OTHER"
        },
        {
          "name": "Registry",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "21 Years to 90 Years"
      },
      "enrollment_count": 276,
      "start_date": "2022-10-19",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2025-11-21",
      "last_synced_at": "2026-10-05T11:59:21.272Z",
      "location_count": 5,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04755413"
    },
    {
      "nct_id": "NCT06966362",
      "title": "Varenicline for Smoking Reduction in Veterans Not Ready To Quit",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Veterans",
        "Tobacco Use Disorder",
        "Cigarette Smoking",
        "Tobacco Dependence"
      ],
      "interventions": [
        {
          "name": "Motivation-Phase Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Motivation-Phase Nicotine Mini-Lozenge",
          "type": "DRUG"
        },
        {
          "name": "Cessation-Phase Combination Nicotine Replacement Therapy (NRT)",
          "type": "DRUG"
        },
        {
          "name": "Cessation-Phase Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Motivation-Phase Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation-Phase Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2026-08-17",
      "completion_date": "2030-06-28",
      "has_results": false,
      "last_update_posted_date": "2026-08-31",
      "last_synced_at": "2026-10-05T11:59:21.272Z",
      "location_count": 4,
      "location_summary": "San Diego, California • Minneapolis, Minnesota • Durham, North Carolina + 1 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06966362"
    },
    {
      "nct_id": "NCT02312934",
      "title": "Nicotinic Treatment of Post-Chemotherapy Subjective Cognitive Impairment: A Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chemo Brain",
        "Chemotherapy-related Cognitive Impairment",
        "Chemo Fog",
        "Breast Cancer",
        "Chemobrain"
      ],
      "interventions": [
        {
          "name": "Transdermal nicotine",
          "type": "DRUG"
        },
        {
          "name": "Placebo Transdermal Patch",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "80 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 80 Years · Female only"
      },
      "enrollment_count": 22,
      "start_date": "2015-08",
      "completion_date": "2018-05",
      "has_results": true,
      "last_update_posted_date": "2020-01-21",
      "last_synced_at": "2026-10-05T11:59:21.272Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02312934"
    },
    {
      "nct_id": "NCT00297492",
      "title": "Gradual vs. Abrupt Cessation Treatment for Smoking",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Reduction Phone Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Abrupt Phone Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Minimal Abrupt Phone Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pre-Quit Nicotine Lozenges",
          "type": "DRUG"
        },
        {
          "name": "Post-Quit Nicotine Lozenges",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of Vermont",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 750,
      "start_date": "2006-01",
      "completion_date": "2008-02",
      "has_results": true,
      "last_update_posted_date": "2013-09-20",
      "last_synced_at": "2026-10-05T11:59:21.272Z",
      "location_count": 1,
      "location_summary": "Burlington, Vermont",
      "locations": [
        {
          "city": "Burlington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00297492"
    }
  ]
}