{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+6+mg%2FmL",
    "query": {
      "intervention": "Nicotine 6 mg/mL"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+6+mg%2FmL&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-09T06:41:24.832Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04378907",
      "title": "Assessing Electronic Cigarette Nicotine Flux",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use"
      ],
      "interventions": [
        {
          "name": "Cigarette Smoker/ECIG users: 0 mg/ml nicotine concentration",
          "type": "OTHER"
        },
        {
          "name": "Cigarette Smokers/ECIG users: 6 mg/ml nicotine concentration",
          "type": "OTHER"
        },
        {
          "name": "Cigarette Smokers/ECIG users: 15 mg/ml nicotine concentration",
          "type": "OTHER"
        },
        {
          "name": "Cigarette Smokers/ECIG users: 30 mg/ml nicotine concentration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 33,
      "start_date": "2021-01-05",
      "completion_date": "2023-02-01",
      "has_results": true,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-09-09T06:41:24.832Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04378907"
    },
    {
      "nct_id": "NCT02179034",
      "title": "Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Nicotine Dependence, Other Tobacco Product"
      ],
      "interventions": [
        {
          "name": "Nicotine",
          "type": "DRUG"
        },
        {
          "name": "Low Dose Menthol",
          "type": "OTHER"
        },
        {
          "name": "High Dose Menthol",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "18 Years to 20 Years"
      },
      "enrollment_count": 59,
      "start_date": "2014-10-23",
      "completion_date": "2017-06-12",
      "has_results": false,
      "last_update_posted_date": "2020-05-04",
      "last_synced_at": "2026-09-09T06:41:24.832Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02179034"
    },
    {
      "nct_id": "NCT03473483",
      "title": "Cigarette Harm Reduction With Electronic Cigarette Use",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence",
        "Tobacco Toxicity",
        "Nicotine Dependence, Cigarettes",
        "Cardiovascular Risk Factor",
        "Nicotine Withdrawal"
      ],
      "interventions": [
        {
          "name": "SREC",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2022-08-01",
      "completion_date": "2026-03-31",
      "has_results": false,
      "last_update_posted_date": "2022-12-09",
      "last_synced_at": "2026-09-09T06:41:24.832Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03473483"
    },
    {
      "nct_id": "NCT03742817",
      "title": "Effects of e-Cigarettes on Perceptions and Behavior",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarettes"
      ],
      "interventions": [
        {
          "name": "e-Cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2019-02-01",
      "completion_date": "2020-03-01",
      "has_results": false,
      "last_update_posted_date": "2023-07-11",
      "last_synced_at": "2026-09-09T06:41:24.832Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03742817"
    },
    {
      "nct_id": "NCT03625986",
      "title": "Does Switching to Nicotine Containing Electronic Cigarettes Reduce Health Risk Markers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Dependence"
      ],
      "interventions": [
        {
          "name": "Nicotine-Containing Electronic Cigarette",
          "type": "OTHER"
        },
        {
          "name": "Non-Nicotine Electronic Cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 105,
      "start_date": "2022-04-22",
      "completion_date": "2024-02-23",
      "has_results": true,
      "last_update_posted_date": "2025-03-27",
      "last_synced_at": "2026-09-09T06:41:24.832Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03625986"
    },
    {
      "nct_id": "NCT03168191",
      "title": "Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Nicotine",
          "type": "DRUG"
        },
        {
          "name": "Experimental Flavor",
          "type": "OTHER"
        },
        {
          "name": "Menthol Flavor",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "18 Years to 20 Years"
      },
      "enrollment_count": 56,
      "start_date": "2017-05-02",
      "completion_date": "2019-02-25",
      "has_results": false,
      "last_update_posted_date": "2020-05-04",
      "last_synced_at": "2026-09-09T06:41:24.832Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03168191"
    },
    {
      "nct_id": "NCT03843047",
      "title": "Electronic Cigarette Unit Price Manipulations in the Experimental Tobacco Marketplace",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "3 mg/mL nicotine strength e-liquid",
          "type": "DRUG"
        },
        {
          "name": "6 mg/mL nicotine strength e-liquid",
          "type": "DRUG"
        },
        {
          "name": "12 mg/mL nicotine strength e-liquid",
          "type": "DRUG"
        },
        {
          "name": "24 mg/mL nicotine strength e-liquid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Virginia Polytechnic Institute and State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 81,
      "start_date": "2019-03-01",
      "completion_date": "2021-09-30",
      "has_results": false,
      "last_update_posted_date": "2022-11-22",
      "last_synced_at": "2026-09-09T06:41:24.832Z",
      "location_count": 1,
      "location_summary": "Roanoke, Virginia",
      "locations": [
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03843047"
    },
    {
      "nct_id": "NCT04038515",
      "title": "Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Nicotine",
        "E-liquid Flavors"
      ],
      "interventions": [
        {
          "name": "Nicotine 0 mg/mL",
          "type": "DRUG"
        },
        {
          "name": "Nicotine 6 mg/mL",
          "type": "DRUG"
        },
        {
          "name": "Nicotine 12 mg/mL",
          "type": "DRUG"
        },
        {
          "name": "Nicotine 24 mg/mL",
          "type": "DRUG"
        },
        {
          "name": "'Menthol' flavor",
          "type": "OTHER"
        },
        {
          "name": "'Menthol/Mint' flavor",
          "type": "OTHER"
        },
        {
          "name": "'Green Apple' flavor",
          "type": "OTHER"
        },
        {
          "name": "'Watermelon' flavor",
          "type": "OTHER"
        },
        {
          "name": "'Unflavored'",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 54,
      "start_date": "2022-10-27",
      "completion_date": "2024-06-03",
      "has_results": false,
      "last_update_posted_date": "2024-08-05",
      "last_synced_at": "2026-09-09T06:41:24.832Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04038515"
    },
    {
      "nct_id": "NCT02612701",
      "title": "E-Cigarette Aerosol, Conventional Cigarette Smoke, and Myocardial Perfusion",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Artery Disease",
        "Myocardial Perfusion"
      ],
      "interventions": [
        {
          "name": "Cigarettes",
          "type": "OTHER"
        },
        {
          "name": "E-cigarettes (nicotine free e-liquid)",
          "type": "OTHER"
        },
        {
          "name": "E-cigarettes (low nicotine e-liquid)",
          "type": "OTHER"
        },
        {
          "name": "E-cigarettes (high nicotine e-liquid)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "18 Years to 49 Years"
      },
      "enrollment_count": 20,
      "start_date": "2015-10",
      "completion_date": "2020-10",
      "has_results": false,
      "last_update_posted_date": "2021-02-04",
      "last_synced_at": "2026-09-09T06:41:24.832Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02612701"
    },
    {
      "nct_id": "NCT03169101",
      "title": "Cognition and Smoking Relapse (HCS)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "Behavioral counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 274,
      "start_date": "2016-07-01",
      "completion_date": "2022-04-25",
      "has_results": true,
      "last_update_posted_date": "2024-05-10",
      "last_synced_at": "2026-09-09T06:41:24.832Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03169101"
    }
  ]
}