{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+Gum&page=2",
    "query": {
      "intervention": "Nicotine Gum",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+Gum&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-26T19:56:14.327Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04994444",
      "title": "Preloading With Nicotine Replacement Therapy in HIV-positive Smokers to Improve Self-Efficacy and Quit Attempts",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Tobacco Use Cessation"
      ],
      "interventions": [
        {
          "name": "Nicoderm CQ 21Mg/24Hr Transdermal System",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 49,
      "start_date": "2021-09-01",
      "completion_date": "2024-04-30",
      "has_results": true,
      "last_update_posted_date": "2025-04-06",
      "last_synced_at": "2026-09-26T19:56:14.327Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04994444"
    },
    {
      "nct_id": "NCT00060814",
      "title": "Combination Pharmacotherapy for Smoking Cessation Among Methadone Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Tobacco Use Disorder"
      ],
      "interventions": [
        {
          "name": "Combined intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "National Institute on Drug Abuse (NIDA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 28,
      "start_date": "2002-06",
      "completion_date": "2002-12",
      "has_results": false,
      "last_update_posted_date": "2017-01-12",
      "last_synced_at": "2026-09-26T19:56:14.327Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00060814"
    },
    {
      "nct_id": "NCT02323438",
      "title": "Assess Biomarkers of Tobacco Exposure and Nicotine Pharmacokinetics in Smokers After a 5-Day In-Clinic Confinement Switch to an Electronic Cigarette or Nicotine Gum",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking"
      ],
      "interventions": [
        {
          "name": "Usual Brand Cigarette",
          "type": "OTHER"
        },
        {
          "name": "Electronic Cigarette #1",
          "type": "OTHER"
        },
        {
          "name": "Electronic Cigarette #2",
          "type": "OTHER"
        },
        {
          "name": "Leading U.S. Nicotine Gum",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "R.J. Reynolds Vapor Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 153,
      "start_date": "2014-12",
      "completion_date": "2015-05",
      "has_results": false,
      "last_update_posted_date": "2018-06-01",
      "last_synced_at": "2026-09-26T19:56:14.327Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02323438"
    },
    {
      "nct_id": "NCT04971954",
      "title": "Using Nicotine to Reverse Age-related Auditory Processing Deficits",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Auditory Perceptual Impairment",
        "Aging"
      ],
      "interventions": [
        {
          "name": "Nicotine gum",
          "type": "OTHER"
        },
        {
          "name": "Placebo gum",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 48,
      "start_date": "2022-02-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-10",
      "last_synced_at": "2026-09-26T19:56:14.327Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04971954"
    },
    {
      "nct_id": "NCT06506162",
      "title": "Abuse Liability and Appeal of Oral Nicotine Products",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Flavor",
          "type": "OTHER"
        },
        {
          "name": "Nicotine concentration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "21 Years to 25 Years"
      },
      "enrollment_count": 320,
      "start_date": "2024-02-09",
      "completion_date": "2028-02-14",
      "has_results": false,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-09-26T19:56:14.327Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06506162"
    },
    {
      "nct_id": "NCT05020899",
      "title": "Quit For Life (QFL): Smoking Cessation Among Chinese Smokers Living With HIV",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation",
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "Sessions with a trained counselor",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cell phone messages",
          "type": "OTHER"
        },
        {
          "name": "Offered nicotine replacement therapy",
          "type": "OTHER"
        },
        {
          "name": "Self-help guide for quitting smoking",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Boston Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 109,
      "start_date": "2022-02-24",
      "completion_date": "2023-08-01",
      "has_results": true,
      "last_update_posted_date": "2024-12-12",
      "last_synced_at": "2026-09-26T19:56:14.327Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05020899"
    },
    {
      "nct_id": "NCT03719391",
      "title": "United States Pre-Market Tobacco Application Pharmacokinetics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence",
        "Nicotine Dependence, Cigarettes",
        "Tobacco Use",
        "Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "Virginia Tobacco flavored JUUL 5% ENDS",
          "type": "OTHER"
        },
        {
          "name": "Cool Mint flavored JUUL 5% ENDS",
          "type": "OTHER"
        },
        {
          "name": "Mango flavored JUUL 5% ENDS",
          "type": "OTHER"
        },
        {
          "name": "Creme Brulee flavored JUUL 5% ENDS",
          "type": "OTHER"
        },
        {
          "name": "VUSE Solo e-cigarette",
          "type": "OTHER"
        },
        {
          "name": "Nicorette White Ice Mint 4mg nicotine polacrilex gum",
          "type": "OTHER"
        },
        {
          "name": "Usual Brand combustible cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Juul Labs, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 67,
      "start_date": "2018-10-19",
      "completion_date": "2018-11-28",
      "has_results": false,
      "last_update_posted_date": "2021-06-14",
      "last_synced_at": "2026-09-26T19:56:14.327Z",
      "location_count": 1,
      "location_summary": "Overland Park, Kansas",
      "locations": [
        {
          "city": "Overland Park",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03719391"
    },
    {
      "nct_id": "NCT01309217",
      "title": "Dissemination of Tobacco Tactics for Hospitalized Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Tobacco Tactics Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1528,
      "start_date": "2011-07",
      "completion_date": "2014-03",
      "has_results": false,
      "last_update_posted_date": "2014-11-18",
      "last_synced_at": "2026-09-26T19:56:14.327Z",
      "location_count": 6,
      "location_summary": "Grand Rapids, Michigan • Livonia, Michigan • Muskegon, Michigan + 2 more",
      "locations": [
        {
          "city": "Grand Rapids",
          "state": "Michigan"
        },
        {
          "city": "Livonia",
          "state": "Michigan"
        },
        {
          "city": "Muskegon",
          "state": "Michigan"
        },
        {
          "city": "Muskegon",
          "state": "Michigan"
        },
        {
          "city": "Oakland",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01309217"
    },
    {
      "nct_id": "NCT00482690",
      "title": "Analysis of Aldehyde Biomarkers of Exposure and Host Response",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "nicotine polacrilex",
          "type": "DRUG"
        },
        {
          "name": "nicotine transdermal system",
          "type": "DRUG"
        },
        {
          "name": "nicotine inhaler",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 35,
      "start_date": "2005-08-23",
      "completion_date": "2007-09-09",
      "has_results": true,
      "last_update_posted_date": "2023-09-07",
      "last_synced_at": "2026-09-26T19:56:14.327Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00482690"
    },
    {
      "nct_id": "NCT01116986",
      "title": "Identifying Optimal Smoking Cessation Intervention Components (Cessation)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking",
        "Smoking Cessation",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Counseling before quit attempt",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Minimal In-person counseling during quit attempt",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Intensive in-person counseling during the quit attempt",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Minimal phone counseling during the quit attempt",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Intensive phone counseling during the quit attempt",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Long Term Nicotine Patch+ Nicotine Gum During Quit Attempt",
          "type": "DRUG"
        },
        {
          "name": "Short Term Nicotine Patch + Nicotine Gum during the quit attempt",
          "type": "DRUG"
        },
        {
          "name": "Pre-Quit Nicotine Gum",
          "type": "DRUG"
        },
        {
          "name": "Pre-Quit Nicotine Patch",
          "type": "DRUG"
        },
        {
          "name": "Pre-Quit Nicotine Patch + Pre-Quit Nicotine Gum",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 637,
      "start_date": "2010-06",
      "completion_date": "2014-05",
      "has_results": true,
      "last_update_posted_date": "2015-12-11",
      "last_synced_at": "2026-09-26T19:56:14.327Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01116986"
    }
  ]
}