{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+Oral+Pouch&page=2", "query": { "intervention": "Nicotine Oral Pouch", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 27, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+Oral+Pouch&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+Oral+Pouch&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-02T10:47:33.823Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06043362", "title": "Use of Nicotine Pouches Among Daily Smokers", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Tobacco Dependence" ], "interventions": [ { "name": "0 mg nicotine pouch", "type": "OTHER" }, { "name": "3 mg nicotine pouch", "type": "OTHER" }, { "name": "6 mg nicotine pouch", "type": "OTHER" }, { "name": "Smooth nicotine pouch", "type": "OTHER" }, { "name": "Wintergreen nicotine pouch", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Milton S. Hershey Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "21 Years to 70 Years" }, "enrollment_count": 375, "start_date": "2024-09-17", "completion_date": "2028-08", "has_results": false, "last_update_posted_date": "2025-10-01", "last_synced_at": "2026-10-02T10:47:33.823Z", "location_count": 2, "location_summary": "Hershey, Pennsylvania • Houston, Texas", "locations": [ { "city": "Hershey", "state": "Pennsylvania" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06043362" }, { "nct_id": "NCT05280769", "title": "Effects of an Oral Nicotine Product in Smokeless Tobacco Users", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Tobacco Use" ], "interventions": [ { "name": "oral nicotine pouch - 2 mg", "type": "OTHER" }, { "name": "oral nicotine pouch - 4 mg", "type": "OTHER" }, { "name": "oral nicotine pouch - 8 mg", "type": "OTHER" }, { "name": "Smokeless tobacco", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Virginia Commonwealth University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 31, "start_date": "2022-08-23", "completion_date": "2023-11-28", "has_results": false, "last_update_posted_date": "2024-10-02", "last_synced_at": "2026-10-02T10:47:33.823Z", "location_count": 1, "location_summary": "Richmond, Virginia", "locations": [ { "city": "Richmond", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT05280769" }, { "nct_id": "NCT07165808", "title": "Effect of Product Characteristics on the Abuse Liability of Nicotine Pouches", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Nicotine Addiction" ], "interventions": [ { "name": "Nicotine pouch: Low dose", "type": "OTHER" }, { "name": "Nicotine pouch: High dose", "type": "OTHER" }, { "name": "Low pH", "type": "OTHER" }, { "name": "High pH", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "35 Years", "sex": "ALL", "summary": "21 Years to 35 Years" }, "enrollment_count": 84, "start_date": "2026-02-13", "completion_date": "2028-01", "has_results": false, "last_update_posted_date": "2026-02-27", "last_synced_at": "2026-10-02T10:47:33.823Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT07165808" }, { "nct_id": "NCT06315881", "title": "Informing Oral Nicotine Pouch Regulations to Promote Public Health", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Tobacco-Related Carcinoma" ], "interventions": [ { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Cigarette", "type": "DRUG" }, { "name": "Nicotine Oral Pouch", "type": "DRUG" }, { "name": "Smokeless Tobacco", "type": "DRUG" }, { "name": "Survey Administration", "type": "OTHER" }, { "name": "Text Message-Based Navigation Intervention", "type": "OTHER" } ], "intervention_types": [ "PROCEDURE", "DRUG", "OTHER" ], "sponsor": "Ohio State University Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 160, "start_date": "2025-01-13", "completion_date": "2028-08-31", "has_results": false, "last_update_posted_date": "2026-08-17", "last_synced_at": "2026-10-02T10:47:33.823Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT06315881" }, { "nct_id": "NCT01964807", "title": "Cardiovascular Assessment of the Effects of Tobacco and Nicotine Delivery Products", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Adverse Effect of Other Agents Primarily Affecting the Cardiovascular System, Initial Encounter" ], "interventions": [ { "name": "Cigarette, NIDA test type with 16.6 mg nicotine", "type": "OTHER" }, { "name": "Cigarette, NIDA test type with <0.45 mg nicotine", "type": "OTHER" }, { "name": "Electronic cigarette with 18 mg/ml nicotine", "type": "OTHER" }, { "name": "Electronic Cigarette with no nicotine", "type": "OTHER" }, { "name": "Moist snuff", "type": "OTHER" }, { "name": "Sham Smoking", "type": "OTHER" }, { "name": "Secondhand cigarette smoke (SHS)", "type": "OTHER" }, { "name": "Conditioned, filtered air", "type": "OTHER" }, { "name": "Sham Moist Snuff", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 81, "start_date": "2013-11-03", "completion_date": "2021-05-31", "has_results": false, "last_update_posted_date": "2021-12-27", "last_synced_at": "2026-10-02T10:47:33.823Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01964807" }, { "nct_id": "NCT06077240", "title": "Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Smoking", "Smoking Behaviors", "Nicotine Dependence" ], "interventions": [ { "name": "E-cigarette with 2.4% Nicotine with Menthol and Tobacco Flavors", "type": "BEHAVIORAL" }, { "name": "E-cigarette with 2.4% Nicotine with Tobacco Flavor Only", "type": "BEHAVIORAL" }, { "name": "E-cigarette with 5% Nicotine with Menthol and Tobacco Flavors", "type": "BEHAVIORAL" }, { "name": "E-cigarette with 5% Nicotine with Tobacco Flavor Only", "type": "BEHAVIORAL" }, { "name": "Tobacco Pouches with 3mg Nicotine with Menthol and Tobacco Flavors", "type": "BEHAVIORAL" }, { "name": "Tobacco Pouches with 3mg Nicotine with Tobacco Flavor Only", "type": "BEHAVIORAL" }, { "name": "Tobacco Pouches with 6mg Nicotine with Menthol and Tobacco Flavors", "type": "BEHAVIORAL" }, { "name": "Tobacco Pouches with 6mg Nicotine with Tobacco Flavor Only", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 256, "start_date": "2024-08-20", "completion_date": "2028-04-01", "has_results": false, "last_update_posted_date": "2026-03-19", "last_synced_at": "2026-10-02T10:47:33.823Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT06077240" }, { "nct_id": "NCT05423340", "title": "Effect of E-Liquid Flavor on Respiratory Symptoms in People Using Electronic Nicotine Delivery Systems", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Electronic Cigarette Use" ], "interventions": [ { "name": "E-cigarette Flavor", "type": "OTHER" }, { "name": "Tobacco Free Nicotine Pouch", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Roswell Park Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "21 Years to 55 Years" }, "enrollment_count": 163, "start_date": "2022-06-12", "completion_date": "2024-10-03", "has_results": true, "last_update_posted_date": "2026-06-04", "last_synced_at": "2026-10-02T10:47:33.823Z", "location_count": 1, "location_summary": "Buffalo, New York", "locations": [ { "city": "Buffalo", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05423340" }, { "nct_id": "NCT07095140", "title": "Studying the Effects of Nicotine Concentration and Flavor on Alcohol Use in Young Adults", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Alcohol-Related Carcinoma" ], "interventions": [ { "name": "Ecological Momentary Assessment", "type": "OTHER" }, { "name": "Monitoring", "type": "OTHER" }, { "name": "Nicotine Oral Pouch", "type": "DRUG" }, { "name": "Survey Administration", "type": "OTHER" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "Ohio State University Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "30 Years", "sex": "ALL", "summary": "21 Years to 30 Years" }, "enrollment_count": 20, "start_date": "2025-09-03", "completion_date": "2027-12-31", "has_results": false, "last_update_posted_date": "2025-11-26", "last_synced_at": "2026-10-02T10:47:33.823Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT07095140" }, { "nct_id": "NCT07128329", "title": "Acute Effects of Oral Nicotine Pouches", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Nicotine Pouch Self-Administration", "Nicotine Pharmacokinetic Study", "Nicotine Pharmacodynamic Study" ], "interventions": [ { "name": "Nicotine Pouches", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Johns Hopkins University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 120, "start_date": "2025-11-21", "completion_date": "2027-04-01", "has_results": false, "last_update_posted_date": "2026-02-17", "last_synced_at": "2026-10-02T10:47:33.823Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT07128329" }, { "nct_id": "NCT07503925", "title": "THRIVE Study: Understanding How Oral Nicotine Pouches Affect Public Health", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Tobacco-Related Carcinoma" ], "interventions": [ { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Nicotine Oral Pouch", "type": "DRUG" }, { "name": "Survey Administration", "type": "OTHER" }, { "name": "Text Message-Based Navigation Intervention", "type": "OTHER" } ], "intervention_types": [ "PROCEDURE", "DRUG", "OTHER" ], "sponsor": "Ohio State University Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 15, "start_date": "2026-06-26", "completion_date": "2027-12-31", "has_results": false, "last_update_posted_date": "2026-08-17", "last_synced_at": "2026-10-02T10:47:33.823Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT07503925" } ] }