{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+Pouches&page=2", "query": { "intervention": "Nicotine Pouches", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 39, "total_pages": 4, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+Pouches&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+Pouches&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-01T16:21:38.103Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07213947", "title": "Comparison of Demand and Substitution for Nicotine Pouches as a Function of Nicotine Dosage", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Tobacco Use", "Nicotine Pouch Self-Administration" ], "interventions": [ { "name": "Nicotine Pouch Dosage", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "William Middleton", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1360, "start_date": "2025-12-04", "completion_date": "2026-01-02", "has_results": false, "last_update_posted_date": "2026-05-01", "last_synced_at": "2026-10-01T16:21:38.103Z", "location_count": 1, "location_summary": "Lexington, Kentucky", "locations": [ { "city": "Lexington", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT07213947" }, { "nct_id": "NCT06763536", "title": "Oral Nicotine Pouches Versus Nicotine Replacement Therapy to Reduce Cigarette Use for Smokers in Rural Appalachia", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cigarette Smoking-Related Carcinoma" ], "interventions": [ { "name": "Carbon Monoxide Measurement", "type": "OTHER" }, { "name": "Nicotine Lozenge", "type": "OTHER" }, { "name": "Oral Nicotine Pouch", "type": "OTHER" }, { "name": "Nicotine Patch", "type": "OTHER" }, { "name": "Survey Administration", "type": "OTHER" }, { "name": "Check-in Phone Calls", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Ohio State University Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 1000, "start_date": "2025-06-13", "completion_date": "2028-12-31", "has_results": false, "last_update_posted_date": "2026-06-30", "last_synced_at": "2026-10-01T16:21:38.103Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT06763536" }, { "nct_id": "NCT06303115", "title": "CSD231005 Nicotine Pouch Biomarkers of Exposure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Tobacco Use", "Smoking" ], "interventions": [ { "name": "Nicotine Pouch P1312914, 4 mg nicotine", "type": "OTHER" }, { "name": "Nicotine Pouch P1312915, 8 mg nicotine", "type": "OTHER" }, { "name": "Nicotine Pouch P1013215, 8 mg nicotine", "type": "OTHER" }, { "name": "Nicotine Pouch P1013218, 10 mg nicotine", "type": "OTHER" }, { "name": "Nicotine Pouch P1012919, 12 mg nicotine", "type": "OTHER" }, { "name": "Smoking Abstinence", "type": "OTHER" }, { "name": "Continued UB cigarette smoking", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "RAI Services Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "21 Years to 60 Years" }, "enrollment_count": 200, "start_date": "2024-08-22", "completion_date": "2025-01-15", "has_results": false, "last_update_posted_date": "2025-04-11", "last_synced_at": "2026-10-01T16:21:38.103Z", "location_count": 5, "location_summary": "Bentonville, Arkansas • Lexington, Kentucky • Springfield, Missouri + 2 more", "locations": [ { "city": "Bentonville", "state": "Arkansas" }, { "city": "Lexington", "state": "Kentucky" }, { "city": "Springfield", "state": "Missouri" }, { "city": "Knoxville", "state": "Tennessee" }, { "city": "Richardson", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06303115" }, { "nct_id": "NCT04755348", "title": "A Study to Assess the Pharmacokinetics of Oral Nicotine Pouches and Lozenges in Healthy Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Tobacco Use", "Tobacco Smoking", "Cigarette Smoking" ], "interventions": [ { "name": "Product A", "type": "OTHER" }, { "name": "Product B", "type": "OTHER" }, { "name": "Product C", "type": "OTHER" }, { "name": "Product D", "type": "OTHER" }, { "name": "Product E", "type": "OTHER" }, { "name": "Product F", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "British American Tobacco (Investments) Limited", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "21 Years to 60 Years" }, "enrollment_count": 36, "start_date": "2021-02-18", "completion_date": "2021-03-25", "has_results": false, "last_update_posted_date": "2021-03-30", "last_synced_at": "2026-10-01T16:21:38.103Z", "location_count": 1, "location_summary": "Overland Park, Kansas", "locations": [ { "city": "Overland Park", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04755348" }, { "nct_id": "NCT06372899", "title": "Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "E-cigarette Use", "Cigarette Smoking", "Harm Reduction", "Tobacco Use" ], "interventions": [ { "name": "E-cigarettes", "type": "OTHER" }, { "name": "Oral nicotine pouches", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Abramson Cancer Center at Penn Medicine", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 200, "start_date": "2024-10-02", "completion_date": "2028-03-31", "has_results": false, "last_update_posted_date": "2026-03-12", "last_synced_at": "2026-10-01T16:21:38.103Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT06372899" }, { "nct_id": "NCT05335915", "title": "Acute Pharmacokinetic and Pharmacodynamic Effects of \"Tobacco-Free\" Oral Nicotine Pouches in Smokers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Nicotine Withdrawal", "Nicotine Addiction", "Drug Effect" ], "interventions": [ { "name": "Nicotine", "type": "OTHER" }, { "name": "Cigarette", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Johns Hopkins University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 71, "start_date": "2022-07-27", "completion_date": "2025-08-29", "has_results": true, "last_update_posted_date": "2026-07-23", "last_synced_at": "2026-10-01T16:21:38.103Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT05335915" }, { "nct_id": "NCT04846088", "title": "A Study to Characterize Nicotine Pharmacokinetics and Subjective Effects of Nicotine Pouches in Adult Cigarette Smokers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Tobacco Use", "Tobacco Smoking" ], "interventions": [ { "name": "Product A", "type": "OTHER" }, { "name": "Product B", "type": "OTHER" }, { "name": "Product C", "type": "OTHER" }, { "name": "Product D", "type": "OTHER" }, { "name": "Product E", "type": "OTHER" }, { "name": "Product F", "type": "OTHER" }, { "name": "Product G", "type": "OTHER" }, { "name": "Product H", "type": "OTHER" }, { "name": "Product I", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "British American Tobacco (Investments) Limited", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "22 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "22 Years to 65 Years" }, "enrollment_count": 42, "start_date": "2021-04-05", "completion_date": "2021-06-02", "has_results": false, "last_update_posted_date": "2022-12-07", "last_synced_at": "2026-10-01T16:21:38.103Z", "location_count": 1, "location_summary": "Overland Park, Kansas", "locations": [ { "city": "Overland Park", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04846088" }, { "nct_id": "NCT06605924", "title": "Oral Nicotine Pouch Marketing Features Influence on Perceptions", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Tobacco Use" ], "interventions": [ { "name": "Tobacco-free", "type": "OTHER" }, { "name": "Discrete", "type": "OTHER" }, { "name": "Convenient", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Johns Hopkins Bloomberg School of Public Health", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "13 Years", "maximum_age": "120 Years", "sex": "ALL", "summary": "13 Years to 120 Years" }, "enrollment_count": 5133, "start_date": "2025-05-12", "completion_date": "2025-11-18", "has_results": false, "last_update_posted_date": "2026-07-23", "last_synced_at": "2026-10-01T16:21:38.103Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT06605924" }, { "nct_id": "NCT07476144", "title": "Nicotine Pouch Pharmacokinetics Abuse Liability", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Smoking Behaviors" ], "interventions": [ { "name": "Participants will place the pouch between their top lip and their gum for 30 minutes as per use instructions.", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "JT International SA", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "22 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "22 Years to 65 Years" }, "enrollment_count": 55, "start_date": "2026-01-08", "completion_date": "2026-10", "has_results": false, "last_update_posted_date": "2026-08-19", "last_synced_at": "2026-10-01T16:21:38.103Z", "location_count": 2, "location_summary": "Knoxville, Tennessee • San Antonio, Texas", "locations": [ { "city": "Knoxville", "state": "Tennessee" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07476144" }, { "nct_id": "NCT05081154", "title": "CSD201002: Study to Assess Nicotine Uptake From P10 Nicotine Pouches", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Smoking", "Tobacco Use" ], "interventions": [ { "name": "Product A", "type": "OTHER" }, { "name": "Product B", "type": "OTHER" }, { "name": "Product C", "type": "OTHER" }, { "name": "Product D", "type": "OTHER" }, { "name": "Product E", "type": "OTHER" }, { "name": "Product F", "type": "OTHER" }, { "name": "Product G", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "RAI Services Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "21 Years to 60 Years" }, "enrollment_count": 36, "start_date": "2021-10-20", "completion_date": "2021-11-24", "has_results": false, "last_update_posted_date": "2022-06-27", "last_synced_at": "2026-10-01T16:21:38.103Z", "location_count": 1, "location_summary": "Knoxville, Tennessee", "locations": [ { "city": "Knoxville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT05081154" } ] }