{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+Replacement+Treatment+%28NRT%29&page=3",
    "query": {
      "intervention": "Nicotine Replacement Treatment (NRT)",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 403,
    "total_pages": 41,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+Replacement+Treatment+%28NRT%29&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+Replacement+Treatment+%28NRT%29&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-07T14:31:13.290Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00309296",
      "title": "Longitudinal Care: Smoking Reduction to Aid Cessation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Diseases"
      ],
      "interventions": [
        {
          "name": "smoking cessation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National Institutes of Health (NIH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 443,
      "start_date": "2005-11",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2011-02-14",
      "last_synced_at": "2026-10-07T14:31:13.290Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00309296"
    },
    {
      "nct_id": "NCT02302859",
      "title": "Mobile Media-Rich Interactive Guideline System (MMRIGS) Pilot Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use Cessation"
      ],
      "interventions": [
        {
          "name": "Nicotine Patch",
          "type": "DRUG"
        },
        {
          "name": "Questionnaires",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pamphlet",
          "type": "OTHER"
        },
        {
          "name": "Phone Counseling Sessions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Saliva Test",
          "type": "OTHER"
        },
        {
          "name": "Smart phone",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2015-01",
      "completion_date": "2016-03",
      "has_results": true,
      "last_update_posted_date": "2020-01-27",
      "last_synced_at": "2026-10-07T14:31:13.290Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02302859"
    },
    {
      "nct_id": "NCT05224050",
      "title": "Heart Rate Variability Biofeedback for Smoking Cessation Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "Cognitive-Behavioral Smoking Cessation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Heart Rate Variability Biofeedback",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Nicotine patch",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "21 Years to 50 Years"
      },
      "enrollment_count": 28,
      "start_date": "2021-11-29",
      "completion_date": "2023-06-15",
      "has_results": true,
      "last_update_posted_date": "2024-05-01",
      "last_synced_at": "2026-10-07T14:31:13.290Z",
      "location_count": 1,
      "location_summary": "New Brunswick, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05224050"
    },
    {
      "nct_id": "NCT01040260",
      "title": "Low-Cost Contingency Management for Smoking Cessation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use Cessation"
      ],
      "interventions": [
        {
          "name": "Counseling",
          "type": "OTHER"
        },
        {
          "name": "Contingency management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine patches",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 103,
      "start_date": "2009-06",
      "completion_date": "2012-05",
      "has_results": true,
      "last_update_posted_date": "2018-06-06",
      "last_synced_at": "2026-10-07T14:31:13.290Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01040260"
    },
    {
      "nct_id": "NCT05671380",
      "title": "A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Disparities",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use Cessation",
        "Cardiovascular Diseases",
        "Tobacco Use",
        "Smoking",
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Longitudinal Proactive Outreach (LPO).",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Ask-Advice-Connect (AAC)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 700,
      "start_date": "2023-05-05",
      "completion_date": "2028-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-10-07T14:31:13.290Z",
      "location_count": 3,
      "location_summary": "Minneapolis, Minnesota • Rochester, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05671380"
    },
    {
      "nct_id": "NCT03927989",
      "title": "Tobacco Treatment in the Context of Lung Cancer Screening",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Text messaging plus nicotine replacement therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Care at Lung Cancer Screening",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 48,
      "start_date": "2019-04-15",
      "completion_date": "2024-02-01",
      "has_results": true,
      "last_update_posted_date": "2024-11-22",
      "last_synced_at": "2026-10-07T14:31:13.290Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03927989"
    },
    {
      "nct_id": "NCT06098144",
      "title": "Smoking Cessation Program in the Construction Sector",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking Cessation",
        "Tobacco Use Cessation",
        "Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "Nicorette",
          "type": "DRUG"
        },
        {
          "name": "Tobacco Quit-line",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Brief Behavioral Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Intensive Behavioral Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 608,
      "start_date": "2024-04-10",
      "completion_date": "2027-07-28",
      "has_results": false,
      "last_update_posted_date": "2026-08-21",
      "last_synced_at": "2026-10-07T14:31:13.290Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06098144"
    },
    {
      "nct_id": "NCT04634071",
      "title": "Tobacco Treatment Optimization and Preferences During Concurrent Cancer Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Smoking Cessation",
        "Cancer, Treatment-Related"
      ],
      "interventions": [
        {
          "name": "Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Bupropion",
          "type": "DRUG"
        },
        {
          "name": "Long-acting nicotine replacement therapy",
          "type": "DRUG"
        },
        {
          "name": "Low-intensity counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "High-intensity counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "No nicotine replacement therapy",
          "type": "OTHER"
        },
        {
          "name": "Nicotine Replacement Products",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Joseph Valentino, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 126,
      "start_date": "2021-01-12",
      "completion_date": "2026-01-02",
      "has_results": false,
      "last_update_posted_date": "2026-02-02",
      "last_synced_at": "2026-10-07T14:31:13.290Z",
      "location_count": 3,
      "location_summary": "Bowling Green, Kentucky • Lexington, Kentucky • Owensboro, Kentucky",
      "locations": [
        {
          "city": "Bowling Green",
          "state": "Kentucky"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Owensboro",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04634071"
    },
    {
      "nct_id": "NCT00218296",
      "title": "Comparison Across Treatment Conditions to Reduce Smokeless Tobacco Use",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Tobacco Use Disorder"
      ],
      "interventions": [
        {
          "name": "Usual Care Group",
          "type": "DRUG"
        },
        {
          "name": "Reduction Group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 332,
      "start_date": "2006-11",
      "completion_date": "2009-01",
      "has_results": true,
      "last_update_posted_date": "2017-10-16",
      "last_synced_at": "2026-10-07T14:31:13.290Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00218296"
    },
    {
      "nct_id": "NCT03405129",
      "title": "Project Phoenix: Pilot Intervention for Smokers Who Are Not Ready to Quit Smoking",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation",
        "Motivation"
      ],
      "interventions": [
        {
          "name": "Phoenix",
          "type": "BEHAVIORAL"
        },
        {
          "name": "NRT order button",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Factoid",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 152,
      "start_date": "2018-10-17",
      "completion_date": "2022-05-18",
      "has_results": false,
      "last_update_posted_date": "2023-05-11",
      "last_synced_at": "2026-10-07T14:31:13.290Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03405129"
    }
  ]
}