{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+lozenge+%28NRT%29&page=5",
    "query": {
      "intervention": "Nicotine lozenge (NRT)",
      "page": 5
    },
    "page_size": 10
  },
  "pagination": {
    "page": 5,
    "page_size": 10,
    "total_count": 145,
    "total_pages": 15,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+lozenge+%28NRT%29&page=6&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+lozenge+%28NRT%29&page=4&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-18T12:54:40.063Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01892813",
      "title": "Dissemination of a Tailored Tobacco Quitline for Rural Veteran Smokers",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Nicotine Dependence",
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "Nicotine replacement therapy - Transdermal nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "Nicotine replacement therapy - Nicotine gum",
          "type": "DRUG"
        },
        {
          "name": "Nicotine replacement therapy - Nicotine lozenge",
          "type": "DRUG"
        },
        {
          "name": "Bupropion",
          "type": "DRUG"
        },
        {
          "name": "Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Combination pharmacotherapy - Transdermal nicotine patch + nicotine gum",
          "type": "DRUG"
        },
        {
          "name": "Combination pharmacotherapy - Transdermal nicotine patch + nicotine lozenge",
          "type": "DRUG"
        },
        {
          "name": "Combination pharmacotherapy - Transdermal nicotine patch + bupropion",
          "type": "DRUG"
        },
        {
          "name": "Tobacco quitline referral",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tailored behavioral intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Alcohol use risk reduction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral activation for depressive symptoms",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral management of postcessation weight gain",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Mark Vander Weg",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 411,
      "start_date": "2013-07",
      "completion_date": "2018-01",
      "has_results": false,
      "last_update_posted_date": "2017-07-11",
      "last_synced_at": "2026-10-18T12:54:40.063Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01892813"
    },
    {
      "nct_id": "NCT01592695",
      "title": "Tailored Tobacco Quitline for Rural Veterans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cigarette Smoking"
      ],
      "interventions": [
        {
          "name": "Nicotine replacement therapy - transdermal nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "Tailored behavioral intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tobacco quit line referral",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine replacement therapy - nicotine gum",
          "type": "DRUG"
        },
        {
          "name": "Nicotine replacement therapy - nicotine lozenge",
          "type": "DRUG"
        },
        {
          "name": "Bupropion Sustained Release",
          "type": "DRUG"
        },
        {
          "name": "Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Combination pharmacotherapy - transdermal nicotine patch + nicotine gum",
          "type": "DRUG"
        },
        {
          "name": "Combination pharmacotherapy - transdermal nicotine patch + nicotine lozenge",
          "type": "DRUG"
        },
        {
          "name": "Combination pharmacotherapy - transdermal nicotine patch + bupropion",
          "type": "DRUG"
        },
        {
          "name": "Alcohol use risk reduction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral activation for the treatment of depression",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral management of post-cessation weight gain",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Iowa City Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 63,
      "start_date": "2012-06",
      "completion_date": "2013-06",
      "has_results": true,
      "last_update_posted_date": "2019-08-02",
      "last_synced_at": "2026-10-18T12:54:40.063Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01592695"
    },
    {
      "nct_id": "NCT05030272",
      "title": "Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use Disorder",
        "Mental Illness",
        "Recurring Major Depressive Disorder",
        "Bipolar Disorder",
        "Schizophrenia",
        "Schizoaffective Disorder",
        "Persistent Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Quit on the Go App (formerly \"Learn to Quit \" App)",
          "type": "DEVICE"
        },
        {
          "name": "Brief advice",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "Smartphone coaching",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine gum",
          "type": "DRUG"
        },
        {
          "name": "Nicotine Lozenges",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 343,
      "start_date": "2021-09-21",
      "completion_date": "2025-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-10-18T12:54:40.063Z",
      "location_count": 3,
      "location_summary": "Buffalo, New York • Durham, North Carolina • Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05030272"
    },
    {
      "nct_id": "NCT04461288",
      "title": "Engaging Sexual and Gender Minority Cigarette Smokers Into Social Media-based Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation",
        "Nicotine Dependence",
        "Tobacco Use",
        "Cigarette Smoking"
      ],
      "interventions": [
        {
          "name": "Social media-based education, counseling, and support",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine replacement therapies (NRT)",
          "type": "OTHER"
        },
        {
          "name": "Gamification",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 121,
      "start_date": "2020-05-01",
      "completion_date": "2022-05-30",
      "has_results": false,
      "last_update_posted_date": "2022-09-21",
      "last_synced_at": "2026-10-18T12:54:40.063Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04461288"
    },
    {
      "nct_id": "NCT02721082",
      "title": "Changing the Default for Tobacco Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Tobacco Use Cessation"
      ],
      "interventions": [
        {
          "name": "Opt Out Treatment Program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine Replacement Therapy",
          "type": "DRUG"
        },
        {
          "name": "Opt In Treatment Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2016-09-01",
      "completion_date": "2020-12-09",
      "has_results": true,
      "last_update_posted_date": "2022-12-01",
      "last_synced_at": "2026-10-18T12:54:40.063Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02721082"
    },
    {
      "nct_id": "NCT06088862",
      "title": "Evaluate Harm Reduction Products as a Second Line Intervention for Adult Smokers Who Do Not Quit With NRT",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Smoking Cessation",
        "Harm Reduction"
      ],
      "interventions": [
        {
          "name": "Nicoderm",
          "type": "DRUG"
        },
        {
          "name": "Nicorette 4Mg Chewing Gum",
          "type": "DRUG"
        },
        {
          "name": "Nicorette Lozenge Product",
          "type": "DRUG"
        },
        {
          "name": "BIDI e-cigarette",
          "type": "OTHER"
        },
        {
          "name": "on!",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Rose Research Center, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "22 Years to 65 Years"
      },
      "enrollment_count": 4,
      "start_date": "2023-12-27",
      "completion_date": "2024-04-30",
      "has_results": false,
      "last_update_posted_date": "2025-03-30",
      "last_synced_at": "2026-10-18T12:54:40.063Z",
      "location_count": 2,
      "location_summary": "Charlotte, North Carolina • Raleigh, North Carolina",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06088862"
    },
    {
      "nct_id": "NCT05111041",
      "title": "Smokeless Tobacco Cessation Intervention for Firefighters",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smokeless Tobacco Cessation"
      ],
      "interventions": [
        {
          "name": "#EnufSnuff.TXT- First Responder",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enough Snuff Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2022-01-25",
      "completion_date": "2024-01-10",
      "has_results": true,
      "last_update_posted_date": "2024-12-13",
      "last_synced_at": "2026-10-18T12:54:40.063Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05111041"
    },
    {
      "nct_id": "NCT03837379",
      "title": "Goal2Quit + NRT Sampling",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoking",
        "Smoking Cessation",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Treatment as Usual",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Goal2Quit + NRT Sampling",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 164,
      "start_date": "2020-06-22",
      "completion_date": "2022-05-18",
      "has_results": true,
      "last_update_posted_date": "2023-05-17",
      "last_synced_at": "2026-10-18T12:54:40.063Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03837379"
    },
    {
      "nct_id": "NCT06745154",
      "title": "Evaluating the Impact of Quitting Using Executive Function Strategy Training (QUEST) on Smoking Cessation in Homeless Young Adult Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoking-Related Carcinoma"
      ],
      "interventions": [
        {
          "name": "Biospecimen Collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Cognitive Assessment",
          "type": "PROCEDURE"
        },
        {
          "name": "Interview",
          "type": "OTHER"
        },
        {
          "name": "Nicotine Replacement",
          "type": "DRUG"
        },
        {
          "name": "Smoking Cessation Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Survey Administration",
          "type": "OTHER"
        },
        {
          "name": "Tobacco Cessation Counseling",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER",
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio State University Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "24 Years",
        "sex": "ALL",
        "summary": "18 Years to 24 Years"
      },
      "enrollment_count": 27,
      "start_date": "2023-06-26",
      "completion_date": "2023-08-30",
      "has_results": false,
      "last_update_posted_date": "2024-12-20",
      "last_synced_at": "2026-10-18T12:54:40.063Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06745154"
    },
    {
      "nct_id": "NCT04199117",
      "title": "Health Systems Reach Interventions Project",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking, Cigarette",
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Combination nicotine patch and nicotine mini-lozenge treatment",
          "type": "DRUG"
        },
        {
          "name": "Monetary incentives for initiating treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Automated tailored outreach",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Care management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Wisconsin Tobacco Quit Line referral",
          "type": "OTHER"
        },
        {
          "name": "Primary care provider referral",
          "type": "OTHER"
        },
        {
          "name": "Untailored outreach",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Multiple smoking cessation coaching calls",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 210,
      "start_date": "2020-03-11",
      "completion_date": "2024-10-16",
      "has_results": true,
      "last_update_posted_date": "2026-10-05",
      "last_synced_at": "2026-10-18T12:54:40.063Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04199117"
    }
  ]
}