{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+patches%2C+then+varenicline+%28Pre-Quit%29", "query": { "intervention": "Nicotine patches, then varenicline (Pre-Quit)" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 14, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+patches%2C+then+varenicline+%28Pre-Quit%29&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-10-07T08:08:27.506Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02162849", "title": "Reward Sensitivity and Pharmacotherapy for Smoking Cessation", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Tobacco Use Cessation" ], "interventions": [ { "name": "Varenicline", "type": "DRUG" }, { "name": "Nicotine Patch", "type": "DRUG" }, { "name": "Placebo Patch", "type": "DRUG" }, { "name": "Placebo Tablet", "type": "DRUG" }, { "name": "Questionnaires", "type": "BEHAVIORAL" }, { "name": "Counseling Sessions", "type": "BEHAVIORAL" }, { "name": "Lab Session", "type": "OTHER" }, { "name": "Saliva Test", "type": "OTHER" } ], "intervention_types": [ "DRUG", "BEHAVIORAL", "OTHER" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 204, "start_date": "2015-12-14", "completion_date": "2028-02-28", "has_results": false, "last_update_posted_date": "2026-07-16", "last_synced_at": "2026-10-07T08:08:27.506Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02162849" }, { "nct_id": "NCT02050308", "title": "Web-based Smoking Cessation Program for Tribal College Students", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Smoking Cessation" ], "interventions": [ { "name": "Internet-All Nations Breath of Life (I-ANBL)", "type": "OTHER" }, { "name": "Honoring the Gift of Heart Health", "type": "OTHER" }, { "name": "Nicotine gum, Patch, or Lozenge or Zyban® or Chantix®", "type": "DRUG" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "Won Choi, PhD, MPH", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 251, "start_date": "2015-05", "completion_date": "2019-03-31", "has_results": true, "last_update_posted_date": "2021-12-07", "last_synced_at": "2026-10-07T08:08:27.506Z", "location_count": 2, "location_summary": "Kansas City, Kansas • Pablo, Montana", "locations": [ { "city": "Kansas City", "state": "Kansas" }, { "city": "Pablo", "state": "Montana" } ], "official_url": "https://clinicaltrials.gov/study/NCT02050308" }, { "nct_id": "NCT02859142", "title": "Varenicline Augmentation of Patch Outcomes in Heavy Drinkers' Smoking Cessation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Smoking Cessation", "Alcohol Drinking" ], "interventions": [ { "name": "Chantix", "type": "DRUG" }, { "name": "Behavioral Counseling Sessions", "type": "BEHAVIORAL" }, { "name": "NicodermCQ", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 122, "start_date": "2018-03-29", "completion_date": "2020-10-15", "has_results": true, "last_update_posted_date": "2021-09-27", "last_synced_at": "2026-10-07T08:08:27.506Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02859142" }, { "nct_id": "NCT06474299", "title": "The Avenues Study: Dual Use Cessation", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Smoking Cessation", "Electronic Cigarette Use" ], "interventions": [ { "name": "Varenicline", "type": "DRUG" }, { "name": "Nicotine patch", "type": "DRUG" }, { "name": "Dual Focused Cessation Counseling", "type": "BEHAVIORAL" }, { "name": "Smoking Focused Cessation Counseling", "type": "BEHAVIORAL" }, { "name": "Counseling Intensity: 1 Session", "type": "OTHER" }, { "name": "Counseling Intensity: 4 Sessions", "type": "OTHER" } ], "intervention_types": [ "DRUG", "BEHAVIORAL", "OTHER" ], "sponsor": "University of Wisconsin, Madison", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 500, "start_date": "2024-09-24", "completion_date": "2028-07", "has_results": false, "last_update_posted_date": "2026-04-13", "last_synced_at": "2026-10-07T08:08:27.506Z", "location_count": 1, "location_summary": "Madison, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT06474299" }, { "nct_id": "NCT02501265", "title": "Adaptive Pharmacotherapy for Smoking Cessation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Nicotine Dependence" ], "interventions": [ { "name": "Varenicline Standard Protocol", "type": "BEHAVIORAL" }, { "name": "Nicotine Patch Standard Protocol", "type": "BEHAVIORAL" }, { "name": "Varenicline Adaptive Protocol", "type": "DRUG" }, { "name": "Nicotine Adaptive Protocol", "type": "DRUG" } ], "intervention_types": [ "BEHAVIORAL", "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 188, "start_date": "2017-06-06", "completion_date": "2021-05-12", "has_results": true, "last_update_posted_date": "2021-08-19", "last_synced_at": "2026-10-07T08:08:27.506Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02501265" }, { "nct_id": "NCT02551692", "title": "Effects of Smoking Environments on Craving and Smoking (CameraCue2.0)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cigarette Smoking" ], "interventions": [ { "name": "Nicotine Patch", "type": "DRUG" }, { "name": "Varenicline", "type": "DRUG" }, { "name": "Placebo Nicotine Patch", "type": "DRUG" }, { "name": "Placebo Capsule", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 125, "start_date": "2016-01", "completion_date": "2019-01-07", "has_results": true, "last_update_posted_date": "2020-01-18", "last_synced_at": "2026-10-07T08:08:27.506Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02551692" }, { "nct_id": "NCT01553084", "title": "A Comparative Effectiveness & Long Term Health Study in Wisconsin Smokers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Smoking Cessation", "Smoking", "Nicotine Dependence" ], "interventions": [ { "name": "Varenicline", "type": "DRUG" }, { "name": "Nicotine lozenge", "type": "DRUG" }, { "name": "Nicotine Patch", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Wisconsin, Madison", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 1086, "start_date": "2012-05", "completion_date": "2017-08", "has_results": true, "last_update_posted_date": "2020-09-02", "last_synced_at": "2026-10-07T08:08:27.506Z", "location_count": 2, "location_summary": "Madison, Wisconsin • Milwaukee, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" }, { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT01553084" }, { "nct_id": "NCT01560507", "title": "Tailored Smoking Cessation Treatment for LIVE FOR LIFE® Participants", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Cigarette Smoking", "Nicotine Dependence" ], "interventions": [ { "name": "varenicline (Chantix)", "type": "DRUG" }, { "name": "bupropion (Zyban)", "type": "DRUG" }, { "name": "nicotine patches", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 19, "start_date": "2012-05", "completion_date": "2013-07", "has_results": true, "last_update_posted_date": "2014-12-24", "last_synced_at": "2026-10-07T08:08:27.506Z", "location_count": 2, "location_summary": "Durham, North Carolina • Raleigh, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" }, { "city": "Raleigh", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01560507" }, { "nct_id": "NCT04188873", "title": "Cessation Screening Project", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Nicotine Dependence" ], "interventions": [ { "name": "Preparation Varenicline and Standard Duration Varenicline", "type": "DRUG" }, { "name": "Preparation Varenicline and Extended Duration Varenicline", "type": "DRUG" }, { "name": "Standard Duration Varenicline", "type": "DRUG" }, { "name": "Extended Duration Varenicline", "type": "DRUG" }, { "name": "Preparation Combination NRT and Standard Duration Combination NRT", "type": "DRUG" }, { "name": "Preparation Combination NRT and Extended Duration Combination NRT", "type": "DRUG" }, { "name": "Standard Duration Combination NRT", "type": "DRUG" }, { "name": "Extended Duration Combination NRT", "type": "DRUG" }, { "name": "Intensive Counseling", "type": "BEHAVIORAL" }, { "name": "Minimal Counseling", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "University of Wisconsin, Madison", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 538, "start_date": "2020-12-10", "completion_date": "2025-05-08", "has_results": true, "last_update_posted_date": "2026-06-17", "last_synced_at": "2026-10-07T08:08:27.506Z", "location_count": 2, "location_summary": "Madison, Wisconsin • Milwaukee, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" }, { "city": "Milwaukee", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT04188873" }, { "nct_id": "NCT04199117", "title": "Health Systems Reach Interventions Project", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Smoking, Cigarette", "Smoking Cessation" ], "interventions": [ { "name": "Varenicline", "type": "DRUG" }, { "name": "Combination nicotine patch and nicotine mini-lozenge treatment", "type": "DRUG" }, { "name": "Monetary incentives for initiating treatment", "type": "BEHAVIORAL" }, { "name": "Automated tailored outreach", "type": "BEHAVIORAL" }, { "name": "Care management", "type": "BEHAVIORAL" }, { "name": "Wisconsin Tobacco Quit Line referral", "type": "OTHER" }, { "name": "Primary care provider referral", "type": "OTHER" }, { "name": "Untailored outreach", "type": "BEHAVIORAL" }, { "name": "Multiple smoking cessation coaching calls", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL", "OTHER" ], "sponsor": "University of Wisconsin, Madison", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 210, "start_date": "2020-03-11", "completion_date": "2024-10-16", "has_results": true, "last_update_posted_date": "2026-10-05", "last_synced_at": "2026-10-07T08:08:27.506Z", "location_count": 1, "location_summary": "Madison, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT04199117" } ] }