{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+polacrilex&page=3",
    "query": {
      "intervention": "Nicotine polacrilex",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 1395,
    "total_pages": 140,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+polacrilex&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+polacrilex&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-04T22:07:22.454Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00086385",
      "title": "Maintaining Nonsmoking: Older Smokers - 1",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Tobacco Use Disorder"
      ],
      "interventions": [
        {
          "name": "Nicotine polacrilex, Bupropion",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 403,
      "start_date": "2001-09",
      "completion_date": "2009-03",
      "has_results": true,
      "last_update_posted_date": "2015-03-23",
      "last_synced_at": "2026-10-04T22:07:22.454Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00086385"
    },
    {
      "nct_id": "NCT02048917",
      "title": "Optimization of Smoking Cessation Strategies Concurrent With Treatment of Tobacco Related Malignancies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Lung Cancer",
        "Head and Neck Cancer"
      ],
      "interventions": [
        {
          "name": "High Intensity Counseling + Long Acting NRT + PRN NRT",
          "type": "DRUG"
        },
        {
          "name": "High Intensity Counseling + bupropion + PRN NRT",
          "type": "DRUG"
        },
        {
          "name": "High Intensity Counseling + varenicline + PRN NRT",
          "type": "DRUG"
        },
        {
          "name": "High Intensity Counseling + Long Acting NRT",
          "type": "DRUG"
        },
        {
          "name": "High Intensity Counseling + bupropion",
          "type": "DRUG"
        },
        {
          "name": "High Intensity Counseling + varenicline",
          "type": "DRUG"
        },
        {
          "name": "Low Intensity Counseling + Long Acting NRT + PRN NRT",
          "type": "DRUG"
        },
        {
          "name": "Low Intensity Counseling + bupropion + PRN NRT",
          "type": "DRUG"
        },
        {
          "name": "Low Intensity Counseling + varenicline + PRN NRT",
          "type": "DRUG"
        },
        {
          "name": "Low Intensity Counseling + Long Acting NRT",
          "type": "DRUG"
        },
        {
          "name": "Low Intensity Counseling + bupropion",
          "type": "DRUG"
        },
        {
          "name": "Low Intensity Counseling + varenicline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Kentucky",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 93,
      "start_date": "2014-07-22",
      "completion_date": "2019-05-15",
      "has_results": false,
      "last_update_posted_date": "2020-01-29",
      "last_synced_at": "2026-10-04T22:07:22.454Z",
      "location_count": 10,
      "location_summary": "Ashland, Kentucky • Elizabethtown, Kentucky • Hazard, Kentucky + 5 more",
      "locations": [
        {
          "city": "Ashland",
          "state": "Kentucky"
        },
        {
          "city": "Elizabethtown",
          "state": "Kentucky"
        },
        {
          "city": "Hazard",
          "state": "Kentucky"
        },
        {
          "city": "Hazard",
          "state": "Kentucky"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02048917"
    },
    {
      "nct_id": "NCT06239350",
      "title": "Young Adult Tobacco/Nicotine and Cannabis Co-use",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use Disorder",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Contingency management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Text-based support",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "18 Years to 25 Years"
      },
      "enrollment_count": 350,
      "start_date": "2024-05-13",
      "completion_date": "2028-01-03",
      "has_results": false,
      "last_update_posted_date": "2026-07-06",
      "last_synced_at": "2026-10-04T22:07:22.454Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06239350"
    },
    {
      "nct_id": "NCT06795997",
      "title": "Tobacco/Nicotine Purchase Patterns Across SES",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Behaviors",
        "Smoking, Non-Tobacco Products",
        "Smoking, Cigarette"
      ],
      "interventions": [
        {
          "name": "Tax Conditions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Condition",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Virginia Polytechnic Institute and State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 663,
      "start_date": "2024-12-16",
      "completion_date": "2025-03-25",
      "has_results": false,
      "last_update_posted_date": "2025-05-21",
      "last_synced_at": "2026-10-04T22:07:22.454Z",
      "location_count": 1,
      "location_summary": "Roanoke, Virginia",
      "locations": [
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06795997"
    },
    {
      "nct_id": "NCT03927989",
      "title": "Tobacco Treatment in the Context of Lung Cancer Screening",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Text messaging plus nicotine replacement therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Care at Lung Cancer Screening",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 48,
      "start_date": "2019-04-15",
      "completion_date": "2024-02-01",
      "has_results": true,
      "last_update_posted_date": "2024-11-22",
      "last_synced_at": "2026-10-04T22:07:22.454Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03927989"
    },
    {
      "nct_id": "NCT00143325",
      "title": "An Open Label Study That Compares Varenicline to Transdermal Nicotine Patch for Smoking Cessation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "varenicline (CP-526,555)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 730,
      "start_date": "2005-01",
      "completion_date": "2006-06",
      "has_results": false,
      "last_update_posted_date": "2007-06-04",
      "last_synced_at": "2026-10-04T22:07:22.454Z",
      "location_count": 6,
      "location_summary": "Palo Alto, California • Santa Ana, California • Farmington, Connecticut + 3 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Santa Ana",
          "state": "California"
        },
        {
          "city": "Farmington",
          "state": "Connecticut"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Worcester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00143325"
    },
    {
      "nct_id": "NCT04001114",
      "title": "Cigarette Smoking in Smokers With and Without Schizophrenia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Dependence",
        "Schizophrenia"
      ],
      "interventions": [
        {
          "name": "Sampling Research Cigarettes",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 31,
      "start_date": "2021-07-15",
      "completion_date": "2022-12-23",
      "has_results": true,
      "last_update_posted_date": "2024-09-26",
      "last_synced_at": "2026-10-04T22:07:22.454Z",
      "location_count": 1,
      "location_summary": "Catonsville, Maryland",
      "locations": [
        {
          "city": "Catonsville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04001114"
    },
    {
      "nct_id": "NCT04740008",
      "title": "Impact of Low Nicotine Cigarette Messaging on Perceptions and Cigarette Choices",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Smoking",
        "Cigarette"
      ],
      "interventions": [
        {
          "name": "Low Nicotine Content Cigarettes",
          "type": "DRUG"
        },
        {
          "name": "Control message",
          "type": "OTHER"
        },
        {
          "name": "Test message",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Masonic Cancer Center, University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 64,
      "start_date": "2021-04-20",
      "completion_date": "2022-08-24",
      "has_results": false,
      "last_update_posted_date": "2024-02-26",
      "last_synced_at": "2026-10-04T22:07:22.454Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04740008"
    },
    {
      "nct_id": "NCT00756704",
      "title": "The Effectiveness of Smoking Cessation Guidelines in the Emergency Department",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoking"
      ],
      "interventions": [
        {
          "name": "Smoking cessation guideline implementation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 789,
      "start_date": "2008-09",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2011-11-04",
      "last_synced_at": "2026-10-04T22:07:22.454Z",
      "location_count": 2,
      "location_summary": "Des Moines, Iowa • Iowa City, Iowa",
      "locations": [
        {
          "city": "Des Moines",
          "state": "Iowa"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00756704"
    },
    {
      "nct_id": "NCT06001840",
      "title": "Promotion and Mitigation Factors Leading to Illegal Tobacco Purchases",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoking",
        "Nicotine Vaping"
      ],
      "interventions": [
        {
          "name": "Promotion factors",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mitigation strategies",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Virginia Polytechnic Institute and State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2024-01-04",
      "completion_date": "2025-03-31",
      "has_results": true,
      "last_update_posted_date": "2026-02-10",
      "last_synced_at": "2026-10-04T22:07:22.454Z",
      "location_count": 1,
      "location_summary": "Roanoke, Virginia",
      "locations": [
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06001840"
    }
  ]
}