{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+replacement+therapy+%28patch%2C+gum%29%2C+both+arms",
    "query": {
      "intervention": "Nicotine replacement therapy (patch, gum), both arms"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 4,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-28T01:28:14.396Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01120704",
      "title": "Evaluation of Treatments to Improve Smoking Cessation Medication Adherence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking",
        "Smoking Cessation",
        "Adherence",
        "Nicotine Dependence",
        "Motivation"
      ],
      "interventions": [
        {
          "name": "Short Term Combination Nicotine Replacement Therapy (patch + gum)",
          "type": "DRUG"
        },
        {
          "name": "Long Term Combination Nicotine Replacement Therapy (patch + gum)",
          "type": "DRUG"
        },
        {
          "name": "Intensive Maintenance Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Medication Adherence Counseling (CAM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Electronic Medication Monitoring Device (the Helping Hand) + Feedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Automated Adherence Prompting Phone Calls",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 544,
      "start_date": "2010-06",
      "completion_date": "2014-05",
      "has_results": true,
      "last_update_posted_date": "2015-12-11",
      "last_synced_at": "2026-10-28T01:28:14.396Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01120704"
    },
    {
      "nct_id": "NCT07897058",
      "title": "Project E-Shift: A Harm Reduction Intervention for Chronically Unhoused Smokers.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoking Behavior",
        "E-Cigarette Use"
      ],
      "interventions": [
        {
          "name": "E-cigarette",
          "type": "OTHER"
        },
        {
          "name": "Nicotine replacement therapy (patch, gum), both arms",
          "type": "DRUG"
        },
        {
          "name": "CO-contingent financial incentives, both arms",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cessation counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2025-08-05",
      "completion_date": "2026-07-29",
      "has_results": false,
      "last_update_posted_date": "2026-10-27",
      "last_synced_at": "2026-10-28T01:28:14.396Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07897058"
    },
    {
      "nct_id": "NCT00064844",
      "title": "Combination Nicotine Replacement for Alcoholic Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking",
        "Alcoholism"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavior Therapy for alcohol and smoking cessation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicoderm CQ nicotine patch",
          "type": "DRUG"
        },
        {
          "name": "Placebo gum",
          "type": "DRUG"
        },
        {
          "name": "Nicotine gum - Nicorette®",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 96,
      "start_date": "2002-08",
      "completion_date": "2006-07",
      "has_results": true,
      "last_update_posted_date": "2021-08-13",
      "last_synced_at": "2026-10-28T01:28:14.396Z",
      "location_count": 1,
      "location_summary": "Newington, Connecticut",
      "locations": [
        {
          "city": "Newington",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00064844"
    },
    {
      "nct_id": "NCT05683821",
      "title": "BREATHE 2 Clinic Stop-Smoking Treatment Outreach Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Quitting Smoking",
        "Smoking Cessation",
        "Smoking, Cigarette"
      ],
      "interventions": [
        {
          "name": "Text message smoking treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine replacement therapy sampling",
          "type": "DRUG"
        },
        {
          "name": "Wisconsin Tobacco QuitLine Referral",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Referral to Primary Care Provider",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "BREATHE 2 Cessation Study",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Additional modalities to learn about and request treatment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG",
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12376,
      "start_date": "2023-07-24",
      "completion_date": "2025-05-07",
      "has_results": true,
      "last_update_posted_date": "2026-06-26",
      "last_synced_at": "2026-10-28T01:28:14.396Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05683821"
    }
  ]
}