{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+with+Tobacco+Flavor+and+Tobacco+%26+Menthol+Flavor",
    "query": {
      "intervention": "Nicotine with Tobacco Flavor and Tobacco & Menthol Flavor"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 33,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nicotine+with+Tobacco+Flavor+and+Tobacco+%26+Menthol+Flavor&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-09T11:45:17.043Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03502200",
      "title": "Switching to a Vaping Device: Evaluating Risk Reduction Among Quitline Treatment Failures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking, Cigarette"
      ],
      "interventions": [
        {
          "name": "JUUL",
          "type": "DEVICE"
        },
        {
          "name": "Treatment As Usual",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Ohio State University Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "21 Years to 99 Years"
      },
      "enrollment_count": 350,
      "start_date": "2020-10-15",
      "completion_date": "2023-01-31",
      "has_results": true,
      "last_update_posted_date": "2023-07-21",
      "last_synced_at": "2026-10-09T11:45:17.043Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03502200"
    },
    {
      "nct_id": "NCT05499377",
      "title": "The Abuse Liability of a Novel Heated Tobacco Product (IQOS) and Its Feasibility as a Menthol Cigarette Substitute",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "Tobacco product administration and assessment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 33,
      "start_date": "2022-11-28",
      "completion_date": "2023-09-22",
      "has_results": true,
      "last_update_posted_date": "2025-01-31",
      "last_synced_at": "2026-10-09T11:45:17.043Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05499377"
    },
    {
      "nct_id": "NCT05023096",
      "title": "Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Nicotine Delivery System Flavors"
      ],
      "interventions": [
        {
          "name": "Tobacco product administration and assessment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 71,
      "start_date": "2022-04-14",
      "completion_date": "2024-10-15",
      "has_results": true,
      "last_update_posted_date": "2026-04-22",
      "last_synced_at": "2026-10-09T11:45:17.043Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05023096"
    },
    {
      "nct_id": "NCT04143256",
      "title": "Evaluating Selected Constituents in the Exhaled Breath Samples",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use",
        "Cigarette Use, Electronic",
        "Tobacco Use",
        "Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "JUUL ENDS 5% Virginia Tobacco",
          "type": "OTHER"
        },
        {
          "name": "JUUL 3% Virginia Tobacco ENDS",
          "type": "OTHER"
        },
        {
          "name": "JUUL 5% Mint ENDS",
          "type": "OTHER"
        },
        {
          "name": "JUUL 3% Mint ENDS",
          "type": "OTHER"
        },
        {
          "name": "JUUL 5% Menthol ENDS",
          "type": "OTHER"
        },
        {
          "name": "JUUL 3% Menthol ENDS",
          "type": "OTHER"
        },
        {
          "name": "JUUL 5% Mango ENDS",
          "type": "OTHER"
        },
        {
          "name": "JUUL 3% Mango ENDS",
          "type": "OTHER"
        },
        {
          "name": "US Cigarette, Non-menthol - Marlboro Gold King Size",
          "type": "OTHER"
        },
        {
          "name": "US Cigarette, Menthol - Newport King Size",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Juul Labs, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 135,
      "start_date": "2019-10-03",
      "completion_date": "2019-12-13",
      "has_results": false,
      "last_update_posted_date": "2020-02-11",
      "last_synced_at": "2026-10-09T11:45:17.043Z",
      "location_count": 3,
      "location_summary": "Secaucus, New Jersey • Charlotte, North Carolina • Raleigh, North Carolina",
      "locations": [
        {
          "city": "Secaucus",
          "state": "New Jersey"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04143256"
    },
    {
      "nct_id": "NCT07092501",
      "title": "An Experimental Evaluation of Menthol-Flavored Tobacco Accessories",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette",
        "Smoking Behaviors",
        "Cigarette Smoking Behavior"
      ],
      "interventions": [
        {
          "name": "Mentholated cigarette sampling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Hypothetical Policy Scenarios",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Subjective value assessment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Virginia Polytechnic Institute and State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2025-09-01",
      "completion_date": "2025-12-20",
      "has_results": false,
      "last_update_posted_date": "2026-06-04",
      "last_synced_at": "2026-10-09T11:45:17.043Z",
      "location_count": 1,
      "location_summary": "Roanoke, Virginia",
      "locations": [
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07092501"
    },
    {
      "nct_id": "NCT06264154",
      "title": "The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Tobacco Use",
        "Cigarette Smoking",
        "E-Cig Use"
      ],
      "interventions": [
        {
          "name": "E-cigarettes",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Abramson Cancer Center at Penn Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 210,
      "start_date": "2024-08-26",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-02-19",
      "last_synced_at": "2026-10-09T11:45:17.043Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06264154"
    },
    {
      "nct_id": "NCT04521647",
      "title": "Effects of Menthol in E-cigarettes on Smoking Behaviors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Nicotine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 14,
      "start_date": "2022-05-10",
      "completion_date": "2023-07-25",
      "has_results": true,
      "last_update_posted_date": "2026-06-16",
      "last_synced_at": "2026-10-09T11:45:17.043Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04521647"
    },
    {
      "nct_id": "NCT01775787",
      "title": "Effects of Electronic Cigarettes on Nicotine Concentrations",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Health Behavior"
      ],
      "interventions": [
        {
          "name": "Nicotine with Tobacco Flavor and Tobacco & Menthol Flavor",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "UConn Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 27,
      "start_date": "2012-10",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2017-11-30",
      "last_synced_at": "2026-10-09T11:45:17.043Z",
      "location_count": 1,
      "location_summary": "Farmington, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01775787"
    },
    {
      "nct_id": "NCT04088175",
      "title": "Study to Characterize Puffing Topography With Use of JUUL Electronic Nicotine Delivery Systems (ENDS) in Adult, Closed-System ENDS Consumers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Electronic Cigarette Use"
      ],
      "interventions": [
        {
          "name": "JUUL ENDS - Virginia Tobacco 5% nicotine strength",
          "type": "OTHER"
        },
        {
          "name": "JUUL ENDS - Virginia Tobacco 3% nicotine strength",
          "type": "OTHER"
        },
        {
          "name": "JUUL ENDS - Menthol 5% nicotine strength",
          "type": "OTHER"
        },
        {
          "name": "JUUL ENDS - Menthol 3% nicotine strength",
          "type": "OTHER"
        },
        {
          "name": "JUUL ENDS - Mint 5% nicotine strength",
          "type": "OTHER"
        },
        {
          "name": "JUUL ENDS - Mint 3% nicotine strength",
          "type": "OTHER"
        },
        {
          "name": "JUUL ENDS - Mango 5% nicotine strength",
          "type": "OTHER"
        },
        {
          "name": "JUUL ENDS - Mango 3% nicotine strength",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Juul Labs, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 56,
      "start_date": "2019-10-28",
      "completion_date": "2020-01-23",
      "has_results": false,
      "last_update_posted_date": "2021-06-14",
      "last_synced_at": "2026-10-09T11:45:17.043Z",
      "location_count": 2,
      "location_summary": "Burbank, California • Baltimore, Maryland",
      "locations": [
        {
          "city": "Burbank",
          "state": "California"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04088175"
    },
    {
      "nct_id": "NCT06554873",
      "title": "Adaptive Use of Nicotine Substitution to Maintain Smoking Reduction/Abstinence in Nicotine Responders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Smoking Cessation",
        "Harm Reduction"
      ],
      "interventions": [
        {
          "name": "Nicoderm",
          "type": "DRUG"
        },
        {
          "name": "Nicorette 4Mg Chewing Gum",
          "type": "DRUG"
        },
        {
          "name": "Nicorette Lozenge Product",
          "type": "DRUG"
        },
        {
          "name": "NJOY e-cigarette",
          "type": "OTHER"
        },
        {
          "name": "on!",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Rose Research Center, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "22 Years to 65 Years"
      },
      "enrollment_count": 150,
      "start_date": "2024-08-29",
      "completion_date": "2025-12-09",
      "has_results": false,
      "last_update_posted_date": "2026-02-06",
      "last_synced_at": "2026-10-09T11:45:17.043Z",
      "location_count": 2,
      "location_summary": "Charlotte, North Carolina • Raleigh, North Carolina",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06554873"
    }
  ]
}