{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nipple+Sparing+Mastectomy&page=2",
    "query": {
      "intervention": "Nipple Sparing Mastectomy",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 25,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nipple+Sparing+Mastectomy&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nipple+Sparing+Mastectomy&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-01T14:16:21.291Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03892980",
      "title": "Robotic-Assisted da Vinci System Prophylactic Nipple-Sparing Mastectomy",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nipple Sparing Mastectomy"
      ],
      "interventions": [
        {
          "name": "Nipple-Sparing Mastectomy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Intuitive Surgical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 80 Years · Female only"
      },
      "enrollment_count": 145,
      "start_date": "2021-03-26",
      "completion_date": "2029-12-30",
      "has_results": false,
      "last_update_posted_date": "2025-12-18",
      "last_synced_at": "2026-10-01T14:16:21.291Z",
      "location_count": 6,
      "location_summary": "Jacksonville, Florida • Evanston, Illinois • Rochester, Minnesota + 3 more",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "New Hyde Park",
          "state": "New York"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03892980"
    },
    {
      "nct_id": "NCT04596683",
      "title": "Same-Day Discharge After Nipple-sparing Mastectomy or Skin-sparing Mastectomy With Breast Reconstruction",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Mastectomy; Lymphedema",
        "Same Day Surgery",
        "Nipple-sparing Mastectomy",
        "Skin-sparing Mastectomy"
      ],
      "interventions": [
        {
          "name": "Same-day NSM or SSM",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Georgetown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2020-02-04",
      "completion_date": "2022-02-04",
      "has_results": false,
      "last_update_posted_date": "2020-10-22",
      "last_synced_at": "2026-10-01T14:16:21.291Z",
      "location_count": 3,
      "location_summary": "Washington D.C., District of Columbia • Baltimore, Maryland",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04596683"
    },
    {
      "nct_id": "NCT03213249",
      "title": "Bacterial Biofilms in Reconstructive Breast Prostheses Following Mastectomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Breast Implant Infection",
        "Mammoplasty"
      ],
      "interventions": [
        {
          "name": "Normal saline",
          "type": "OTHER"
        },
        {
          "name": "Cefazolin",
          "type": "DRUG"
        },
        {
          "name": "Skin biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "Bilateral skin- or nipple-sparing mastectomies",
          "type": "PROCEDURE"
        },
        {
          "name": "Tissue expander",
          "type": "DEVICE"
        },
        {
          "name": "Breast implant",
          "type": "DEVICE"
        },
        {
          "name": "Autologous flap",
          "type": "PROCEDURE"
        },
        {
          "name": "Acellular dermal matrix sling",
          "type": "OTHER"
        },
        {
          "name": "Gentamicin",
          "type": "DRUG"
        },
        {
          "name": "Bacitracin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG",
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 75 Years · Female only"
      },
      "enrollment_count": 19,
      "start_date": "2017-07-25",
      "completion_date": "2018-09-26",
      "has_results": false,
      "last_update_posted_date": "2019-02-08",
      "last_synced_at": "2026-10-01T14:16:21.291Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03213249"
    },
    {
      "nct_id": "NCT04866992",
      "title": "Prospective Registry Trial for Single Port Robot-assisted Nipple Sparing Mastectomy (SPrNSM)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anatomic Stage IA Breast Cancer AJCC v8",
        "Anatomic Stage IB Breast Cancer AJCC v8",
        "Anatomic Stage IIA Breast Cancer AJCC v8",
        "Anatomic Stage II Breast Cancer AJCC v8",
        "Anatomic Stage I Breast Cancer AJCC v8",
        "Anatomic Stage IIB Breast Cancer AJCC v8",
        "Anatomic Stage IIIA Breast Cancer AJCC v8",
        "Ductal Carcinoma in Situ",
        "Prognostic Stage I Breast Cancer AJCC v8",
        "Prognostic Stage II Breast Cancer AJCC v8",
        "BRCA1 Mutation",
        "BRCA2 Mutation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 10,
      "start_date": "2020-02-01",
      "completion_date": "2021-09-24",
      "has_results": false,
      "last_update_posted_date": "2022-01-21",
      "last_synced_at": "2026-10-01T14:16:21.291Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04866992"
    },
    {
      "nct_id": "NCT05720039",
      "title": "Robotic vs. Open NSM for Early Stage Breast Cancer",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer Female",
        "Breast Cancer",
        "Breast Cancer, Early-Onset",
        "Breast Disease",
        "Breast"
      ],
      "interventions": [
        {
          "name": "Robotic NSM",
          "type": "DEVICE"
        },
        {
          "name": "Open NSM",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Intuitive Surgical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 204,
      "start_date": "2023-05-08",
      "completion_date": "2031-03",
      "has_results": false,
      "last_update_posted_date": "2026-02-24",
      "last_synced_at": "2026-10-01T14:16:21.291Z",
      "location_count": 15,
      "location_summary": "Irvine, California • Los Angeles, California • Jacksonville, Florida + 12 more",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05720039"
    },
    {
      "nct_id": "NCT04447339",
      "title": "Open Nipple Sparing Mastectomy (NSM)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Nipple Sparing Mastectomy"
      ],
      "interventions": [
        {
          "name": "Nipple Sparing Mastectomy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Intuitive Surgical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 75,
      "start_date": "2020-09-21",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-24",
      "last_synced_at": "2026-10-01T14:16:21.291Z",
      "location_count": 5,
      "location_summary": "Evanston, Illinois • Rochester, Minnesota • Queens, New York + 2 more",
      "locations": [
        {
          "city": "Evanston",
          "state": "Illinois"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Queens",
          "state": "New York"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04447339"
    },
    {
      "nct_id": "NCT01969448",
      "title": "Study to Assess Perfusion and Patient Satisfaction in Nipple-Areola Mastectomy With Immediate Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ductal Carcinoma in Situ - Category",
        "Breast Cancer",
        "Prophylactic Mastectomy"
      ],
      "interventions": [
        {
          "name": "Inframammary Fold Incision or Lateral Radial Incision",
          "type": "PROCEDURE"
        },
        {
          "name": "Lateral Radial Incision",
          "type": "PROCEDURE"
        },
        {
          "name": "Inframammary Fold Incision",
          "type": "PROCEDURE"
        },
        {
          "name": "Laser-assisted fluorescence angiography",
          "type": "DEVICE"
        },
        {
          "name": "Indocyanine Green",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 79,
      "start_date": "2013-03-28",
      "completion_date": "2017-04-17",
      "has_results": true,
      "last_update_posted_date": "2018-04-18",
      "last_synced_at": "2026-10-01T14:16:21.291Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01969448"
    },
    {
      "nct_id": "NCT00539227",
      "title": "A Pilot Study to Evaluate Nipple-Areolar Complex (NAC) Sparing Mastectomy",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "NAC Sparing Mastectomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Questionnaire",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BEHAVIORAL"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 37,
      "start_date": "2007-10",
      "completion_date": "2013-07",
      "has_results": false,
      "last_update_posted_date": "2013-08-26",
      "last_synced_at": "2026-10-01T14:16:21.291Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00539227"
    },
    {
      "nct_id": "NCT06153836",
      "title": "Neurotization of the Nipple Areolar Complex to Restore Sensation for Patients With Breast Cancer Undergoing Nipple Sparing Mastectomy and Reconstruction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anatomic Stage 0 Breast Cancer AJCC v8",
        "Anatomic Stage I Breast Cancer AJCC v8",
        "Anatomic Stage IIA Breast Cancer AJCC v8"
      ],
      "interventions": [
        {
          "name": "Neurotization Procedure",
          "type": "PROCEDURE"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "Subcutaneous Mastectomy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 45,
      "start_date": "2023-12-05",
      "completion_date": "2026-11-10",
      "has_results": false,
      "last_update_posted_date": "2026-08-19",
      "last_synced_at": "2026-10-01T14:16:21.291Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06153836"
    },
    {
      "nct_id": "NCT03135392",
      "title": "Sensation After Nipple Sparing Mastectomy and Breast Reconstruction With or Without Neurotized Free Tissue Transfer",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mastectomy",
        "Breast Reconstruction"
      ],
      "interventions": [
        {
          "name": "Breast Reconstruction with Artificial Implant",
          "type": "PROCEDURE"
        },
        {
          "name": "Autologous Breast Reconstruction",
          "type": "PROCEDURE"
        },
        {
          "name": "Neurotization",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Case Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2018-10",
      "completion_date": "2020-10",
      "has_results": false,
      "last_update_posted_date": "2018-11-14",
      "last_synced_at": "2026-10-01T14:16:21.291Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03135392"
    }
  ]
}