{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nitric+Oxide+for+Inhalation",
    "query": {
      "intervention": "Nitric Oxide for Inhalation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 91,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nitric+Oxide+for+Inhalation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-24T04:50:02.191Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05616910",
      "title": "Inhaled Nitric Oxide for Microvascular Dysfunction in Traumatic Brain Injury",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "inhaled nitric oxide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 38,
      "start_date": "2025-04-06",
      "completion_date": "2028-03-28",
      "has_results": false,
      "last_update_posted_date": "2026-06-17",
      "last_synced_at": "2026-09-24T04:50:02.191Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05616910"
    },
    {
      "nct_id": "NCT00867477",
      "title": "PMRR-NO: Pulmonary Metabolic Radiation Response Versus Exhaled Nitric Oxide",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Gastrointestinal Disease",
        "Esophageal Cancer",
        "Lung Cancer"
      ],
      "interventions": [
        {
          "name": "Breathing Test",
          "type": "PROCEDURE"
        },
        {
          "name": "Respiratory Symptoms Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pet Scan",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BEHAVIORAL"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 163,
      "start_date": "2009-03",
      "completion_date": "2014-08",
      "has_results": false,
      "last_update_posted_date": "2014-08-28",
      "last_synced_at": "2026-09-24T04:50:02.191Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00867477"
    },
    {
      "nct_id": "NCT05867914",
      "title": "Early Feasibility Study Evaluating the 3P-100 Device in Subjects With PH-ILD",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension, Pulmonary",
        "Lung Diseases, Interstitial"
      ],
      "interventions": [
        {
          "name": "Inhaled Nitric Oxide (iNO)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Third Pole Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "22 Years to 84 Years"
      },
      "enrollment_count": 5,
      "start_date": "2023-12-04",
      "completion_date": "2024-03-29",
      "has_results": false,
      "last_update_posted_date": "2024-02-14",
      "last_synced_at": "2026-09-24T04:50:02.191Z",
      "location_count": 3,
      "location_summary": "Tampa, Florida • Cincinnati, Ohio • Charleston, South Carolina",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05867914"
    },
    {
      "nct_id": "NCT05801224",
      "title": "Vascular ARDS Recruitment After Inhaled Nitric Oxide",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Distress Syndrome",
        "Ventilation Perfusion Mismatch"
      ],
      "interventions": [
        {
          "name": "Nitric Oxide",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 70,
      "start_date": "2026-07-10",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-18",
      "last_synced_at": "2026-09-24T04:50:02.191Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05801224"
    },
    {
      "nct_id": "NCT02584751",
      "title": "GERD and Anti-Reflux Therapy Between Able-bodied and SCI Individuals",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Gastro Esophageal Reflux Disorder"
      ],
      "interventions": [
        {
          "name": "Omeprazole",
          "type": "DRUG"
        },
        {
          "name": "24 Hour pH Monitor",
          "type": "DEVICE"
        },
        {
          "name": "Pulmonary Function Examination",
          "type": "PROCEDURE"
        },
        {
          "name": "Exhaled Nitric Oxide",
          "type": "PROCEDURE"
        },
        {
          "name": "Exhaled Breath Concentrate (EBC)",
          "type": "PROCEDURE"
        },
        {
          "name": "Bernstein's Acid Clearance Test",
          "type": "PROCEDURE"
        },
        {
          "name": "Esophageal Motility",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "James J. Peters Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 110,
      "start_date": "2016-08",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2016-11-15",
      "last_synced_at": "2026-09-24T04:50:02.191Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02584751"
    },
    {
      "nct_id": "NCT00114413",
      "title": "Evaluation of an Asthma Treatment Strategy Based on Exhaled Nitric Oxide Measurements in Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Asthma"
      ],
      "interventions": [
        {
          "name": "Inhaled corticosteroids",
          "type": "DRUG"
        },
        {
          "name": "eNO measurement",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "12 Years to 20 Years"
      },
      "enrollment_count": 547,
      "start_date": "2004-08",
      "completion_date": "2006-11",
      "has_results": false,
      "last_update_posted_date": "2017-02-10",
      "last_synced_at": "2026-09-24T04:50:02.191Z",
      "location_count": 12,
      "location_summary": "Tucson, Arizona • Denver, Colorado • Washington D.C., District of Columbia + 9 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00114413"
    },
    {
      "nct_id": "NCT06675435",
      "title": "Inhaled Nitric Oxide in Severe Obesity",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Respiratory Insufficiency",
        "Hypoxemic Respiratory Failure",
        "Nitric Oxide"
      ],
      "interventions": [
        {
          "name": "Nitric oxide",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2026-10",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-20",
      "last_synced_at": "2026-09-24T04:50:02.191Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06675435"
    },
    {
      "nct_id": "NCT00041574",
      "title": "Hospital-Based Program for Treatment of Severe Cardiopulmonary Disease With Inhaled Nitric Oxide",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pulmonary Hypertension",
        "Lung Disease",
        "Sickle Cell Disease",
        "Cardiac Transplant",
        "Lung Transplant"
      ],
      "interventions": [
        {
          "name": "Inhaled Nitric Oxide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mallinckrodt",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2002-04",
      "completion_date": "2005-12",
      "has_results": false,
      "last_update_posted_date": "2016-09-09",
      "last_synced_at": "2026-09-24T04:50:02.191Z",
      "location_count": 3,
      "location_summary": "Denver, Colorado • Providence, Rhode Island",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00041574"
    },
    {
      "nct_id": "NCT00608322",
      "title": "Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in Sepsis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Sepsis"
      ],
      "interventions": [
        {
          "name": "Inhaled nitric oxide",
          "type": "DRUG"
        },
        {
          "name": "Sham inhaled nitric oxide",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "National Institute of General Medical Sciences (NIGMS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "14 Years and older"
      },
      "enrollment_count": 49,
      "start_date": "2009-08",
      "completion_date": "2013-04",
      "has_results": true,
      "last_update_posted_date": "2013-07-11",
      "last_synced_at": "2026-09-24T04:50:02.191Z",
      "location_count": 1,
      "location_summary": "Camden, New Jersey",
      "locations": [
        {
          "city": "Camden",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00608322"
    },
    {
      "nct_id": "NCT03748992",
      "title": "A Proof of Concept Study of Inhaled Nitric Oxide for Adults With Pulmonary Non-Tuberculous Mycobacterial Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Nontuberculous Mycobacterium Infection"
      ],
      "interventions": [
        {
          "name": "gNO",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 10,
      "start_date": "2019-01-28",
      "completion_date": "2020-03-26",
      "has_results": true,
      "last_update_posted_date": "2021-05-18",
      "last_synced_at": "2026-09-24T04:50:02.191Z",
      "location_count": 2,
      "location_summary": "Portland, Oregon • Charleston, South Carolina",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03748992"
    }
  ]
}