{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nitric+oxide&page=2",
    "query": {
      "intervention": "Nitric oxide",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Nitric+oxide&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-24T08:16:20.116Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00386737",
      "title": "Development of a Breath Analyzer for Asthma Screening",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Asthma"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Ekips Technologies",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "4 Years to 65 Years"
      },
      "enrollment_count": 2000,
      "start_date": "2004-09",
      "completion_date": "2007-02",
      "has_results": false,
      "last_update_posted_date": "2006-10-12",
      "last_synced_at": "2026-09-24T08:16:20.116Z",
      "location_count": 1,
      "location_summary": "Norman, Oklahoma",
      "locations": [
        {
          "city": "Norman",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00386737"
    },
    {
      "nct_id": "NCT00867477",
      "title": "PMRR-NO: Pulmonary Metabolic Radiation Response Versus Exhaled Nitric Oxide",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Gastrointestinal Disease",
        "Esophageal Cancer",
        "Lung Cancer"
      ],
      "interventions": [
        {
          "name": "Breathing Test",
          "type": "PROCEDURE"
        },
        {
          "name": "Respiratory Symptoms Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pet Scan",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BEHAVIORAL"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 163,
      "start_date": "2009-03",
      "completion_date": "2014-08",
      "has_results": false,
      "last_update_posted_date": "2014-08-28",
      "last_synced_at": "2026-09-24T08:16:20.116Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00867477"
    },
    {
      "nct_id": "NCT03684213",
      "title": "Local Antioxidant Therapy Vasoconstriction Effects in Different Races",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Cardiovascular Diseases",
        "Cardiovascular Risk Factor",
        "Vasoconstriction"
      ],
      "interventions": [
        {
          "name": "Control (Norepinephrine)",
          "type": "DRUG"
        },
        {
          "name": "Norepinephrine + Ascorbic Acid",
          "type": "DRUG"
        },
        {
          "name": "Norepinephrine + L-NAME",
          "type": "DRUG"
        },
        {
          "name": "Norepinephrine + L-NAME + Ascorbic Acid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas at Arlington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 22,
      "start_date": "2018-10-15",
      "completion_date": "2024-06-08",
      "has_results": false,
      "last_update_posted_date": "2024-06-11",
      "last_synced_at": "2026-09-24T08:16:20.116Z",
      "location_count": 1,
      "location_summary": "Arlington, Texas",
      "locations": [
        {
          "city": "Arlington",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03684213"
    },
    {
      "nct_id": "NCT00056433",
      "title": "Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Sickle Cell Anemia"
      ],
      "interventions": [
        {
          "name": "Hydroxyurea",
          "type": "DRUG"
        },
        {
          "name": "L-Arginine",
          "type": "DRUG"
        },
        {
          "name": "Sildenafil",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institutes of Health Clinical Center (CC)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 39,
      "start_date": "2003-03-10",
      "completion_date": "2006-12-27",
      "has_results": false,
      "last_update_posted_date": "2019-11-22",
      "last_synced_at": "2026-09-24T08:16:20.116Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00056433"
    },
    {
      "nct_id": "NCT00711165",
      "title": "Mometasone and Markers of Airway Inflammation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Asthma"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Mometasone Furoate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Creighton University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "19 Years to 50 Years"
      },
      "enrollment_count": 12,
      "start_date": "2005-08",
      "completion_date": "2006-08",
      "has_results": false,
      "last_update_posted_date": "2008-07-08",
      "last_synced_at": "2026-09-24T08:16:20.116Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00711165"
    },
    {
      "nct_id": "NCT01220687",
      "title": "Inhaled Nitric Oxide (iNO) as an Adjunct to Neonatal Resuscitation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Distress Syndrome in Premature Infants",
        "Very Low Birth Weight Baby"
      ],
      "interventions": [
        {
          "name": "iNO",
          "type": "DRUG"
        },
        {
          "name": "Nitrogen",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Minute",
        "maximum_age": "2 Minutes",
        "sex": "ALL",
        "summary": "1 Minute to 2 Minutes"
      },
      "enrollment_count": 33,
      "start_date": "2011-04",
      "completion_date": "2017-05-01",
      "has_results": true,
      "last_update_posted_date": "2020-08-19",
      "last_synced_at": "2026-09-24T08:16:20.116Z",
      "location_count": 2,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01220687"
    },
    {
      "nct_id": "NCT05747508",
      "title": "A Study to Assess Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Hypertension Associated With Pulmonary Fibrosis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pulmonary Fibrosis",
        "Pulmonary Hypertension"
      ],
      "interventions": [
        {
          "name": "INOpulse®",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Placebo",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Long Term Follow Up",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Bellerophon",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 85,
      "start_date": "2017-12-29",
      "completion_date": "2023-12",
      "has_results": false,
      "last_update_posted_date": "2023-02-28",
      "last_synced_at": "2026-09-24T08:16:20.116Z",
      "location_count": 23,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Sacramento, California + 19 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05747508"
    },
    {
      "nct_id": "NCT05867914",
      "title": "Early Feasibility Study Evaluating the 3P-100 Device in Subjects With PH-ILD",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension, Pulmonary",
        "Lung Diseases, Interstitial"
      ],
      "interventions": [
        {
          "name": "Inhaled Nitric Oxide (iNO)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Third Pole Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "22 Years to 84 Years"
      },
      "enrollment_count": 5,
      "start_date": "2023-12-04",
      "completion_date": "2024-03-29",
      "has_results": false,
      "last_update_posted_date": "2024-02-14",
      "last_synced_at": "2026-09-24T08:16:20.116Z",
      "location_count": 3,
      "location_summary": "Tampa, Florida • Cincinnati, Ohio • Charleston, South Carolina",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05867914"
    },
    {
      "nct_id": "NCT05801224",
      "title": "Vascular ARDS Recruitment After Inhaled Nitric Oxide",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Distress Syndrome",
        "Ventilation Perfusion Mismatch"
      ],
      "interventions": [
        {
          "name": "Nitric Oxide",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 70,
      "start_date": "2026-07-10",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-18",
      "last_synced_at": "2026-09-24T08:16:20.116Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05801224"
    },
    {
      "nct_id": "NCT02584751",
      "title": "GERD and Anti-Reflux Therapy Between Able-bodied and SCI Individuals",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Gastro Esophageal Reflux Disorder"
      ],
      "interventions": [
        {
          "name": "Omeprazole",
          "type": "DRUG"
        },
        {
          "name": "24 Hour pH Monitor",
          "type": "DEVICE"
        },
        {
          "name": "Pulmonary Function Examination",
          "type": "PROCEDURE"
        },
        {
          "name": "Exhaled Nitric Oxide",
          "type": "PROCEDURE"
        },
        {
          "name": "Exhaled Breath Concentrate (EBC)",
          "type": "PROCEDURE"
        },
        {
          "name": "Bernstein's Acid Clearance Test",
          "type": "PROCEDURE"
        },
        {
          "name": "Esophageal Motility",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "James J. Peters Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 110,
      "start_date": "2016-08",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2016-11-15",
      "last_synced_at": "2026-09-24T08:16:20.116Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02584751"
    }
  ]
}